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Irene A Barbazetto; Choroidal Thickness in fellow eyes of patients diagnosed with circumscribed choriodal hemangioma.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5906.
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© ARVO (1962-2015); The Authors (2016-present)
The aim of this study was to evaluate the subfoveal choroidal thickness in the fellow eyes of patients with circumscribed choroidal hemangioma,.
In this observational, cross-sectional study, subfoveal choroidal thickness was measured in patients using enhanced depth imaging spectral-domain optical coherence tomography (OCT, Spectralis™, Heidelberg Engineering, Germany). All subjects underwent a comprehensive ophthalmologic examination, including ultrasonography, fluorescein angiography (FA), and indocyanine green angiography (ICG-A) to confirm the diagnosis of circumscribed choroidal hemangioma.
Eight fellow eyes ( 6 right, 2 left) of 8 consecutive choroidal hemangioma patients (3 women, 5 men) with a mean age of 53.8 years (range: 43-74 years) were included in the study. Five patients were emmetropic, 2 patients were myopic (-1.75 and -4 diopter), and 1 patient was hyperopic (+4 diopter). Best-corrected vimsual acuity in all fellow eyes was 20/20. Choroidal hemangioma were located in the macula ( sub foveal):2, superior macula ( not involving the fovea):2, temporal macula:1, nasal to the optic nerve:1, superior to the optic nerve:2. Mean sub foveal choroidal thickness in the fellow eye as measured by enhanced depth imaging using spectral domain OCT was 426.5μm (range: 349 - 498μm).
In this small sample cohort, the subfoveal thickness measured in fellow eyes of choroidal hemangioma patients was increased compared to choroidal thickness as reported in the general population (Margolis R, Spaide RF. A pilot study of enhanced depth imaging opticalcoherence tomography of the choroid in normal eyes. Am J Ophthalmol. 2009May;147(5):811-5. doi: 10.1016/j.ajo.2008.12.008.). This finding may indicate more general choroidal changes in this subset of patients than previously thought based on standard angiography (FA, ICG-A). However, larger studies are needed to confirm this finding.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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