September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
The Relationship between Vitamin D Deficiency and Diabetic Retinopathy: A Systemic Review and Meta-Analysis
Author Affiliations & Notes
  • Jason Zhang
    Ophthalmology, Yale New Haven Hospital , Hamden, Connecticut, United States
  • Anawin Sanguankeo
    Bassett Medical Center, Cooperstown, New York, United States
  • Footnotes
    Commercial Relationships   Jason Zhang, None; Anawin Sanguankeo, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 6312. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Jason Zhang, Anawin Sanguankeo; The Relationship between Vitamin D Deficiency and Diabetic Retinopathy: A Systemic Review and Meta-Analysis. Invest. Ophthalmol. Vis. Sci. 2016;57(12):6312.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : The purpose of this study was to evaluate the evidence for an association between diabetic retinopathy and vitamin D deficiency

Methods : We conducted a systematic review and meta-analysis of 13 observational studies with 9,350 participants who had undergone assessment for both diabetic retinopathy and vitamin D deficiency. Pooled odds ratios and 95% confidence intervals (CIs) were calculated using a random-effect, Mantel-Haenszel analysis

Results : There is a statistically significant association between diabetic retinopathy and vitamin D deficiency with a pooled odds ratio of 1.44 (95% CI: 1.15 to 1.81, P=0.001). There was also a statistically significant lower serum vitamin D level in patient subgroups with diabetic retinopathy vs control groups with a mean difference (MD) of -2.25 ng/mL (95% CI: -3.64 to -0.87, P=0.001)

Conclusions : There is a statistically significant association between vitamin D deficiency and diabetic retinopathy. Vitamin D supplementation as a protective mechanism against the development and progression of diabetic retinopathy warrants further investigation

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×