September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
INTRAOCULAR PRESSURE SPIKES WITHIN THE FIRST POSTOPERATIVE HOURS FOLLOWING STANDARD TRABECULECTOMY: INCIDENCE AND ASSOCIATED FACTORS
Author Affiliations & Notes
  • Vinicius Bergamo
    Escola Paulista de Medicina, São Paulo, Brazil
  • Felipe Daher
    Escola Paulista de Medicina, São Paulo, Brazil
  • Carolina Pelegrini Gracitelli
    Escola Paulista de Medicina, São Paulo, Brazil
  • Tiago S. Prata
    Escola Paulista de Medicina, São Paulo, Brazil
  • Fabio Nishimura Kanadani
    Eye Institute of Medical Science University Hospital, Belo Horizonte, Brazil
  • Syril Dorairaj
    Mayo Clinic, Jacksonville, Florida, United States
  • Footnotes
    Commercial Relationships   Vinicius Bergamo, None; Felipe Daher, None; Carolina Gracitelli, None; Tiago Prata, None; Fabio Kanadani, None; Syril Dorairaj, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 6446. doi:
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      Vinicius Bergamo, Felipe Daher, Carolina Pelegrini Gracitelli, Tiago S. Prata, Fabio Nishimura Kanadani, Syril Dorairaj; INTRAOCULAR PRESSURE SPIKES WITHIN THE FIRST POSTOPERATIVE HOURS FOLLOWING STANDARD TRABECULECTOMY: INCIDENCE AND ASSOCIATED FACTORS. Invest. Ophthalmol. Vis. Sci. 2016;57(12):6446.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : We aimed to investigate the incidence of intraocular pressure (IOP) spikes within the first postoperative hours following standard trabeculectomy, and to determine possible associated factors.

Methods : A multicenter prospective interventional study was carried out. We enrolled consecutive patients undergoing standard trabeculectomy with mytomicin C. Key exclusion criteria were the presence of any other ocular disease (except from cataract) and ocular trauma. All included patients were examined within the first postoperative hours (between hours 1-2 and 4-6), at days 1 and 7. Demographic and ocular data were collected. Main outcomes measurements were IOP values at each time point and the frequency of IOP spikes (defined as IOP≥25 mmHg).

Results : A total of 32 patients were included (mean age 60.7±13.1 years). Mean preoperative IOP and number of antiglaucoma medications were 22.3±7.8 mmHg and 2.9±0.6, respectively. Although IOP was significantly reduced to 12.1±9.1 mmHg at hour 1-2 (p<0.01) and to 11.5±7.2 mmHg at hour 4-6 (p<0.01), IOP spikes were documented in 10% of the cases within the first postoperative hours (IOP range: 26 – 38 mmHg).

Conclusions : Our results suggest that although uncommon, IOP spikes may occur in the first postoperative hours following trabeculectomy. We believe that, in selected cases, such as those with advanced disease and fixation threat, first hours postoperative IOP should be measured, for potential IOP spikes identification and treatment, preventing undesirable outcomes

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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