June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Superior and Inferior Corneal Epithelial Long Term Remodeling in Myopic Corrections with Small Incision Lenticule Extraction (SMILE).
Author Affiliations & Notes
  • Priya Patel
    Dept of Ophthalmology, New York University, West Orange, New Jersey, United States
  • A. John Kanellopoulos
    Dept of Ophthalmology, New York University, West Orange, New Jersey, United States
    Laservision.gr Institute, Athens, Greece
  • Footnotes
    Commercial Relationships   Priya Patel, None; A. Kanellopoulos, Alcon (C), Allegran (C), Avedro (C), i-Optics (C), ISP Surgical (C), Keramed (C), Zeiss (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 163. doi:
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    • Get Citation

      Priya Patel, A. John Kanellopoulos; Superior and Inferior Corneal Epithelial Long Term Remodeling in Myopic Corrections with Small Incision Lenticule Extraction (SMILE).. Invest. Ophthalmol. Vis. Sci. 2017;58(8):163.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess the reactive changes of the superior and inferior corneal epithelial thickness profile induced by small incision lenticule extraction (SMILE) for treatment of myopia.

Methods : This prospective observational study included 16 eyes that were scheduled for myopic SMILE. Optical coherence tomography (OCT) was applied to measure corneal epithelial thickness superiorly and inferiorly within the central 5-mm zone preoperative and postoperatively at various time points.

Results : The average superior epithelial thickness increased from 51.4 ± 2.9 μm preoperatively to 55.9 ± 4.2 μm 6 months postoperatively and the average inferior epithelial thickness increased from 52.8 ± 3.0 μm to 57.2 ± 3.5 μm respectively. Average epithelial thickness increased 0.84% superiorly and 1.28% inferiorly of the preoperative thickness at 24 hours postoperatively, 2.4% and 4.8% at 1 week, 8.7% and 7.4% at 1 month, 9.6% and 8.4% at 3 months respectively.

Conclusions : In this initial study of corneal epithelial thickness remodeling after myopic SMILE, significant epithelial thickening remains stable 3 months after the treatment superiorly and inferiorly.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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