June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Fundus autofluorescence and choroidal thickness by spectral domain optical coherence tomography in dry age-related macular degeneration in mexican population
Author Affiliations & Notes
  • MARLON RAFAEL GARCIA ROA
    RETINA , INSTITUTO MEXICANO DE OFTALMOLOGIA, Queretaro, Queretaro, Mexico
  • Renata Garcia Franco
    RETINA , INSTITUTO MEXICANO DE OFTALMOLOGIA, Queretaro, Queretaro, Mexico
  • Veronica Romero
    RETINA , INSTITUTO MEXICANO DE OFTALMOLOGIA, Queretaro, Queretaro, Mexico
  • Miguel Vazquez
    RETINA , INSTITUTO MEXICANO DE OFTALMOLOGIA, Queretaro, Queretaro, Mexico
  • Ximena Mira
    RETINA , INSTITUTO MEXICANO DE OFTALMOLOGIA, Queretaro, Queretaro, Mexico
  • Footnotes
    Commercial Relationships   MARLON RAFAEL GARCIA ROA, None; Renata Garcia Franco, None; Veronica Romero, None; Miguel Vazquez, None; Ximena Mira, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 37. doi:
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      MARLON RAFAEL GARCIA ROA, Renata Garcia Franco, Veronica Romero, Miguel Vazquez, Ximena Mira; Fundus autofluorescence and choroidal thickness by spectral domain optical coherence tomography in dry age-related macular degeneration in mexican population. Invest. Ophthalmol. Vis. Sci. 2017;58(8):37.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate and quantify fundus autofluorescence patterns in Mexican population with age related macular degeneration , as well as the measurement of choroidal thickness .

Methods : A prospective , comparative transversal study was done during the period from February to November 2016. Patients over 55 years old with no history of other ocular pathology and no history of ocular surgeries 2 months prior, who were given the diagnosis of age-related macular degeneration by complete ophthalmic examination. We assessed the autofluorescence pattern and the subfoveal choroidal thickness manually. Clinical photographs were obtained using a fundus camera , EDI-OCT and Autofluorescence with the BluePeak - Blue Laser Autofluorescence imaging modality using the Spectralis® Heidelberg OCT. Statistics were done using Prism 6 program.

Results : A total of 76 eyes from 50 patients of which 19.7% (n 15) corresponds to geographic atrophy and 80.3% (n 61) have been evaluated to correspond to mild and intermediate dry macular degeneration, with a Mean age of 74.8 years, and the female sex being mostly affected with 68% (n 34), with an average visual acuity of 0.4LogMAr, being found in intermediate and mild dry macular degeneration a predominant autofluorescence pattern, the reticular with 32.8% (N 20) followed by the minimal changes pattern with 22.9% (n 14), normal pattern with 18% (n 11), focal pattern with 14.7% (n 9) , linear ,speckled and patchy pattern with 3.3% (n 2) of each one; and only 1.6% (n 1) of lace-like pattern. While the group of patients with geografic atrophy predominate patchy and diffuse pattern 33.3% (n 5) each one; followed by the in-band pattern with 30% (n3) of the atrophic cases, followed by the in-band pattern with 20% (n 3) , focal and none pattern 6.7% (n1) each one.

Conclusions : Age-related macular degeneration patterns in mexican population findings are similar to those described in caucasic population, phenotypic classification by patterns may allow identification of prognostic determinants and may give important Clues to the understanding of mechanisms of disease.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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