June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
CHOROIDAL CAVERNS AND CHOROIDAL ROUND HYPOREFLECTIVITIES IN GEOGRAPHIC ATROPHY

Author Affiliations & Notes
  • Chiara Giuffre
    Ophthalmology, San Raffaele Scientific Institute, Milano, Italy
  • Eleonora Corbelli
    Ophthalmology, San Raffaele Scientific Institute, Milano, Italy
  • Giorgia Carlotta Albertini
    Ophthalmology, San Raffaele Scientific Institute, Milano, Italy
  • Riccardo Sacconi
    Ophthalmology, San Raffaele Scientific Institute, Milano, Italy
  • Adriano Carnevali
    Ophthalmology, San Raffaele Scientific Institute, Milano, Italy
    Ophthalmology, Università degli studi Magna Graecia, Catanzaro, Italy
  • Luigi De Vitis
    Ophthalmology, San Raffaele Scientific Institute, Milano, Italy
  • Alessandro Rabiolo
    Ophthalmology, San Raffaele Scientific Institute, Milano, Italy
  • Lea Querques
    Ophthalmology, San Raffaele Scientific Institute, Milano, Italy
  • Giuseppe Querques
    Ophthalmology, San Raffaele Scientific Institute, Milano, Italy
  • Francesco Bandello
    Ophthalmology, San Raffaele Scientific Institute, Milano, Italy
  • Footnotes
    Commercial Relationships   Chiara Giuffre, None; Eleonora Corbelli, None; Giorgia Albertini, None; Riccardo Sacconi, None; Adriano Carnevali, None; Luigi De Vitis, None; Alessandro Rabiolo, None; Lea Querques, None; Giuseppe Querques, Alimera Sciences (C), Allergan Inc (C), Bayer Schering-Pharma (C), Heidelberg (C), Novartis (C), Zeiss (C); Francesco Bandello, Alcon (C), Alimera Sciences (C), Allergan Inc (C), Bausch and Lomb (C), Bayer Schering-Pharma (C), Farmila-Thea (C), Genentech (C), Hoffmann-La-Roche (C), Novagali Pharma (C), Novartis (C), Sanofi-Aventis (C), Thrombogenics (C), Zeiss (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 388. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Chiara Giuffre, Eleonora Corbelli, Giorgia Carlotta Albertini, Riccardo Sacconi, Adriano Carnevali, Luigi De Vitis, Alessandro Rabiolo, Lea Querques, Giuseppe Querques, Francesco Bandello; CHOROIDAL CAVERNS AND CHOROIDAL ROUND HYPOREFLECTIVITIES IN GEOGRAPHIC ATROPHY

      . Invest. Ophthalmol. Vis. Sci. 2017;58(8):388.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To describe and investigate “choroidal caverns” and “choroidal round hyporeflectivities “, two optical coherence tomography (OCT) findings in the choroid of patients affected by geography atrophy (GA) secondary to non-neovascular age related macular degeneration (AMD).

Methods : In this retrospective analysis of patients with GA the main outcome measures included evaluation of choroidal caverns and choroidal round hyporeflectivities, their localization and relation with retinal/choroidal structures. Patients underwent a complete ophthalmologic examination including Indocyanine green angiography (ICGA), structural OCT and Optical Coherence Tomography Angiography (OCT-A). The correspondence between the two findings beneath GA on structural OCT and ICGA and OCT-A imaging were analyzed.

Results : Two hundred and one eyes of 120 consecutive patients (mean age 80.5±8.61 years) with GA were included. Fourty-three caverns have been found by OCT in Haller and Sattler layers in 17 eyes of 15 patients, whilst 29 round hyporeflectivities have been found by OCT in both choroidal layers in 21 eyes of other 15 patients. There are several differences between the two findings which include shape, borders and anatomical locations. Choroidal caverns appear on OCT as gaping hyporeflective cavities in the choroid, typically angular without hyperreflective borders often with punctate/linear hyperreflectivities internally; whereas choroidal round hyporeflectivities are round / oval hyporeflectivities, typically delimited by hyperreflective borders characterized by backscattering.

Conclusions : Our results suggest that choroidal round hyporeflectivities beneath GA may represent precursors of choroidal caverns and both may possible arise from non-perfused ghost vessels.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×