June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Assessment of pseudophakic macular oedema in diabetics using macular optical coherence tomography – a prospective cohort study
Author Affiliations & Notes
  • Lin Lu
    Ophthalmology Department, Lincoln County Hospital, Leicester, Leicestershire, United Kingdom
  • Matthew Wakefield
    Ophthalmology, Leicester Royal Infirmary, Leicester, United Kingdom
  • Soon Wai Ch'ng
    Ophthalmology, Manchester Royal Eye Hospital, Manchester, United Kingdom
  • Christopher Knapp
    Ophthalmology Department, Lincoln County Hospital, Leicester, Leicestershire, United Kingdom
  • Footnotes
    Commercial Relationships   Lin Lu, None; Matthew Wakefield, None; Soon Ch'ng, None; Christopher Knapp, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 1804. doi:
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      Lin Lu, Matthew Wakefield, Soon Wai Ch'ng, Christopher Knapp; Assessment of pseudophakic macular oedema in diabetics using macular optical coherence tomography – a prospective cohort study. Invest. Ophthalmol. Vis. Sci. 2017;58(8):1804.

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Abstract

Purpose : To determine and compare the incidence of macular oedema in uncomplicated cataract surgery in healthy and diabetic patients, and to quantify the central macular thickness (CMT) change pre- and post-operatively using macular optical coherence tomography (OCT).

Methods : A prospective study of 15 patients who had uncomplicated cataract surgery at Lincoln County Hospital, United Kingdom, a National Health Service (NHS) district general hospital (DGH) in a rural area. All patients had macular OCT before cataract surgery, and at one month and three months post-operatively to assess CMT and presence of macular oedema. Data analysed and compared between the healthy subjects and diabetes group using student t-Test.

Results : Out of the total 15 patients, 11 were healthy patients and 4 were diabetics. The average age of patients is 71 year-old, 74 among healthy group and 64 in the diabetic groups. Average CMT pre-operatively was 266.55um and 274.5um, at one month 271.64um and 281.25um, and at three months follow up was 280.27um and 287.25um for healthy and diabetics respectively.
Change in CMT in healthy group is 2.03% (t-Test 0.0749, p=0.471) at one month and 4.48% (t-Test 0.0330, p=0.487) at three months after cataract surgery; whereas in patients with diabetes CMT change is 2.52% (t-Test 0.0575, p=0.479) and 4.96% (t-Test 0.0531, p=0.480) at one and three month post-operatively.
Macular oedema was present in one patient in healthy group at three month follow up and no patient developed macular oedema in the diabetic group.

Conclusions : We carried out a prospective study of incidence of pseudophakic macular oedema and CMT change in healthy and diabetic patients at a DGH in the Midlands, UK. Diabetic patients experienced higher increase in CMT after cataract operation in comparison with healthy individuals, but we did not find a higher rate of macular oedema among diabetics. Further study is required with a bigger sample size to investigate the correlation between diabetes and development of pseudophakic macular oedema.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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