June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Averaging Multiple OCT Volumes Improves Visibility of Lamina Cribrosa
Author Affiliations & Notes
  • Youngseok Song
    New York University Langone Eye Center, New York University School of Medicine, New York, New York, United States
  • Daniel Ruminski
    New York University Langone Eye Center, New York University School of Medicine, New York, New York, United States
  • Katie A. Lucy
    New York University Langone Eye Center, New York University School of Medicine, New York, New York, United States
  • Gadi Wollstein
    New York University Langone Eye Center, New York University School of Medicine, New York, New York, United States
  • JOONGWON SHIN
    Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea (the Republic of)
  • Kyung Rim Sung
    Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea (the Republic of)
  • Joel S Schuman
    New York University Langone Eye Center, New York University School of Medicine, New York, New York, United States
  • Hiroshi Ishikawa
    New York University Langone Eye Center, New York University School of Medicine, New York, New York, United States
  • Footnotes
    Commercial Relationships   Youngseok Song, None; Daniel Ruminski, None; Katie Lucy, None; Gadi Wollstein, None; JOONGWON SHIN, None; Kyung Rim Sung, None; Joel Schuman, Zeiss (P); Hiroshi Ishikawa, None
  • Footnotes
    Support  NIH Grant R01-EY013178 and R01-EY025011
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 1311. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Youngseok Song, Daniel Ruminski, Katie A. Lucy, Gadi Wollstein, JOONGWON SHIN, Kyung Rim Sung, Joel S Schuman, Hiroshi Ishikawa; Averaging Multiple OCT Volumes Improves Visibility of Lamina Cribrosa. Invest. Ophthalmol. Vis. Sci. 2017;58(8):1311.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Imaging the lamina cribrosa (LC) has gained importance in the understanding and assessment of glaucoma. However, its clinical utility is limited because typical optical coherence tomography (OCT) images of the LC are of poor quality which precludes performing reliable micro-structural analysis. The purpose of this study was to assess an image enhancement technique involving the averaging of multiple OCT volumes.

Methods : Repetitive OCT volumes (up to 6 volumes scanned on the same day) from 10 healthy eyes (10 subjects) were acquired using Cirrus HD-OCT (Zeiss, Dublin, CA; software version 7.0.3.19; Optic Disc 200x200 scan pattern). All volumes had signal strength of 7 or above. 3D OCT volumes were first registered to each other using the Elastix software, then super-sampled to 800x800x1024 using 3D bi-cubic interpolation. Signal to noise ratio (SNR) and contrast to noise ratio (CNR) were calculated to quantify the image quality of the visible LC. SNR and CNR were then compared between multiple-volume-averaged images and corresponding single volume images using the Wilcoxon test.

Results : Image quality of the visible LC showed notable improvement with multiple volume averaging (Figure 1-6). SNR showed statistically significant improvement from the baseline image quality after 3 or more volumes were averaged (P=0.01), while CNR showed significant improvement from baseline after 2 or more volumes were averaged (P=0.0005) (Figure A, B).

Conclusions : The presented image enhancement technique successfully improved image quality of the visible LC. This technique can be applied to any existing OCT images as long as multiple volumes (minimum of 3 volumes) are available on the same eye from the same session in order to improve image quality.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

 

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×