June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Contrast sensitivity in patients with advanced glaucoma
Author Affiliations & Notes
  • Alessandro Adad Jammal
    Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil
  • Alexandre Soares Castro Reis
    Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil
  • Bruna Gil Ferreira
    Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil
  • Camila Zangalli
    Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil
  • Paul H Artes
    Eye and Vision Research Group, Plymouth University, Plymouth, United Kingdom
  • Vital P Costa
    Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil
  • Footnotes
    Commercial Relationships   Alessandro Jammal, None; Alexandre Reis, None; Bruna Ferreira, None; Camila Zangalli, None; Paul Artes, None; Vital Costa, None
  • Footnotes
    Support  Fight for Sight UK #1736/37
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 2851. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Alessandro Adad Jammal, Alexandre Soares Castro Reis, Bruna Gil Ferreira, Camila Zangalli, Paul H Artes, Vital P Costa; Contrast sensitivity in patients with advanced glaucoma. Invest. Ophthalmol. Vis. Sci. 2017;58(8):2851.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To investigate contrast sensitivity (CS) in glaucoma patients with advanced visual field damage from glaucoma, and to evaluate the precision of two clinical CS tests.

Methods : Thirteen patients with advanced open-angle glaucoma (median age, 68 y, range 47 to 100 y); visual field Mean Deviation, median -28.8 dB, range -31.2 to -21.3 dB; best-corrected visual acuity (BCVA), median +0.10 logMAR (range, 0.00 to +0.28 logMAR) underwent CS testing with the Pelli-Robson (PR) chart (Precision Vision, IL, USA; distance, 1 m) and the Freiburg Visual Acuity and Contrast Test (FrACT, http://michaelbach.de/fract/, version 3.9.3; distance, 1.60 m). Retest measurements were obtained after one week.

Results : Median contrast sensitivity was 1.30 log units (range, 1.05 to 1.65 log units) with the PR chart and 1.35 log units (range, 1.00 to 1.90 log units) with FrACT. Visual acuity explained <50% of the variance in contrast sensitivity.
CS estimates of both tests were closely related (Spearman rank correlation coefficient, 0.86), but CS was 0.08 log units higher with FrACT (median; 95% CI, -0.02 to 0.16 log) than with the PR chart, and Bland-Altman 95% repeatability intervals appeared slightly tighter with the PR chart (Figure).

Conclusions : All patients were able to perform both tests, and almost all patients showed moderate or profound deficits in contrast sensitivity (normal value, ~1.70 log units) despite near-normal visual acuity. Contrast sensitivity should be routinely evaluated alongside visual acuity to monitor foveal visual function in patients with advanced glaucoma.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

 

Bland-Altman 95% intervals of repeatability for contrast sensitivity with the Pelli-Robson chart (C) and FrACT (D). Visual fields examples (Humphrey Field Analyzer, SITA 10-2 test, stimulus size III) are shown for 2 patients (A, B; highlighted data points). Data points are color coded for visual acuity (see E).

Bland-Altman 95% intervals of repeatability for contrast sensitivity with the Pelli-Robson chart (C) and FrACT (D). Visual fields examples (Humphrey Field Analyzer, SITA 10-2 test, stimulus size III) are shown for 2 patients (A, B; highlighted data points). Data points are color coded for visual acuity (see E).

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×