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Roger Goldberg, Michael Chen, Conor Leahy, Kevin Meng, Mary K Durbin; Automated Montage OCT Angiography for Wide-Field Visualization of Retinal Pathologies. Invest. Ophthalmol. Vis. Sci. 2017;58(8):640.
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© ARVO (1962-2015); The Authors (2016-present)
To obtain automated montages of optical coherence tomography (OCT) angiography en-face images, thereby providing a wider and more complete view of the retina vasculature and perfusion status across a range of retinal diseases.
10 subjects with retinal disease were imaged using a CIRRUSTM HD-OCT 5000 AngioPlex device (ZEISS, Dublin, CA). Multiple OCT angiography scans were acquired at differing fixation points for each subject. By controlling the position of the device's internal fixation target, the overlap between adjacent scans was maintained at approximately 30-40%. Montages were then generated using a custom automated image-stitching algorithm, which transforms and blends the images together into a single mosaic.
OCT angiography montages were created for patients with diabetic retinopathy, branch retinal vein occlusion (BRVO), and age-related macular degeneration. Representative images show OCT angiography montages (superficial layer) for two patients with diabetic retinopathy. Montage images were able to consistently capture the posterior 55°.
Creating montage images of OCT angiography scans enables wide-field visualization of the retina. This can be done in a semi-automated fashion to capture the majority of the posterior pole. This high-quality, non-invasive imaging capability may be useful to clinicians for both the diagnosis and treatment over time of a range of retinal disease.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
Montage OCT angiography show the vascular flow over the posterior 55 degrees in a patient with diabetic retinopathy.
Mongtage OCT angiography shows temporal macular microaneurysms and peripheral retinal non-perfusion with capillary dropout in a patient with diabetic retinopathy.
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