June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Effect of "I-stent Inject" implantation on macular and optic nerve vessel density in
OCT-angiography
Author Affiliations & Notes
  • Viktoria Müller
    Department of Ophthalmology, University of Muenster Medical Center, Muenster, Germany
  • Maged alnawaiseh
    Department of Ophthalmology, University of Muenster Medical Center, Muenster, Germany
  • Nicole Eter
    Department of Ophthalmology, University of Muenster Medical Center, Muenster, Germany
  • Footnotes
    Commercial Relationships   Viktoria Müller, None; Maged alnawaiseh, None; Nicole Eter, (Novartis, Bayer, Allergan (F), Bayer, Novartis, Allergan, Alimera Sciences, Roche (C), Novartis, Bayer, Allergan, Heidelberg Engineering, Alimera (R)
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 724. doi:
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    • Get Citation

      Viktoria Müller, Maged alnawaiseh, Nicole Eter; Effect of "I-stent Inject" implantation on macular and optic nerve vessel density in
      OCT-angiography. Invest. Ophthalmol. Vis. Sci. 2017;58(8):724.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate the impact of "I-stent Inject" implantation on the macular and optic nerve perfusion measured by OCT-angiography (OCTA).

Methods : This prospective study includes 10 eyes of 10 patients with a primary open-angle glaucoma (POWG) before and after “I-stent Inject” Implantation combined with cataract surgery. The OCTA was performed using AngioVue (Optovue Inc, Fremont, California, USA). The vessel density in the macula (3x3mm image size) and the optic nerve head (4.5x4.5mm image size) was determined before and 4 weeks after surgery for analysis.

Results : The difference betweene the pre- and postoperative intraocular pressur (IOP) was not significant (p = 0,212). The vessel density in the superficial OCT-angiogram (whole-enface image) improved significantly after“I-stent Inject" implantation (p = 0.005). The differences in mean vessel density before and after surgery in the deep retinal OCT angiogram and in the OCT angiogram of the optic nerve head were not significant (deep retinal OCT angiogram of the macula: p = 0.076; OCT angiogram of the optic nerve head: p = 0.320).

Conclusions : The vessel density in the superficial retinal OCT angiogram improved significantly after surgery eventhough reduction of IOP was not significant. OCT A is a novel method which can help monitoring glaucoma patients.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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