June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Evaluation of foveal avascular zone in diabetic patients with or without macular edema by swept source optical coherence tomography angiography
Author Affiliations & Notes
  • Don-Il Ham
    Samsung Medical Center, Ophthal, Sungkyunkwan Univ Sch of Med, Seoul, Korea (the Republic of)
  • Sung Min Kim
    Samsung Medical Center, Ophthal, Sungkyunkwan Univ Sch of Med, Seoul, Korea (the Republic of)
  • Mingui Kong
    Samsung Medical Center, Ophthal, Sungkyunkwan Univ Sch of Med, Seoul, Korea (the Republic of)
  • Footnotes
    Commercial Relationships   Don-Il Ham, None; Sung Min Kim, None; Mingui Kong, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 1666. doi:
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      Don-Il Ham, Sung Min Kim, Mingui Kong; Evaluation of foveal avascular zone in diabetic patients with or without macular edema by swept source optical coherence tomography angiography. Invest. Ophthalmol. Vis. Sci. 2017;58(8):1666.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To reveal the meaningful change in superficial and deep foveal avascular zone (FAZ) of diabetic patients by using optical coherence tomography angiography (OCTA).

Methods : This is a retrospective, cross-sectional study which included 75 eyes of 62 patients who had undergone OCTA of macular area. Patients were divided into three groups for analysis; diabetic patients with central macular edema (DME+), diabetic patients without central macular edema (DME-), and normal control group. Swept source OCTA within 3 x 3 - mm zone of macula was performed for all patients. By using commercially available ImageJ software, superficial and deep FAZ area was measured.

Results : Mean superficial FAZ (sFAZ) area among three groups showed no significant differences (p=0.136). However, mean deep FAZ (dFAZ) area among three groups showed significant differences (p=0.000) and it was the largest in DME+ group (0.764 ± 0.293mm2) and the smallest in normal controls (0.444 ± 0.145mm2).

Conclusions : Compared to normal controls, dFAZ enlargement was significant in diabetic patients and it was more prominent in DME+ group. On the other hand, sFAZ showed no statistical significance in their size differences among three groups. In evaluation of diabetic retinopathy, enlargement of dFAZ might be more important than the change in sFAZ.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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