June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Omidria® versus Epinephrine: A Retrospective Review of Intraoperative Maintenance of Mydriasis
Author Affiliations & Notes
  • Joshua Nunn
    Ophthalmology, Penn State Hershey Medical Center, Hershey, Pennsylvania, United States
  • Shruti Sudhakar
    Penn State Hershey Medical Center, Hershey, Pennsylvania, United States
  • Ingrid U Scott
    Ophthalmology, Penn State Hershey Medical Center, Hershey, Pennsylvania, United States
  • Seth Pantanelli
    Ophthalmology, Penn State Hershey Medical Center, Hershey, Pennsylvania, United States
  • Footnotes
    Commercial Relationships   Joshua Nunn, None; Shruti Sudhakar, None; Ingrid Scott, None; Seth Pantanelli, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 1829. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Joshua Nunn, Shruti Sudhakar, Ingrid U Scott, Seth Pantanelli; Omidria® versus Epinephrine: A Retrospective Review of Intraoperative Maintenance of Mydriasis. Invest. Ophthalmol. Vis. Sci. 2017;58(8):1829.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To compare the relative efficacy of phenylephrine 1.0%-ketorolac 0.3% (Omidria®) versus epinephrine in the maintenance of mydriasis during cataract surgery.

Methods : This study was approved by the local Institutional Review Board. Surgical videos of eyes that underwent cataract surgery with intraocular lens implantation at an academic medical center between 08/2015 and 06/2016 and which received intracameral Omidria® or epinephrine were reviewed retrospectively. A single examiner who was masked with respect to intracameral mydriatic agent administered reviewed each surgical video and measured the intraoperative pupil diameter at 1 minute intervals for the duration of the surgery. Preoperative white-to-white measurements were used as a reference to calculate pupil diameters.

Results : The study included 46 eyes (19 Omidria®, 27 Epinephrine) from 46 patients. The two patient groups were similar with respect to age, gender, race, baseline intraocular pressure, white-to-white distance, axial length, use of tamsulosin, and baseline pupil diameter. There was no statistically significant difference in the mean area under the curve change from baseline pupil diameter between the two groups (0.85 versus 0.44, respectively; p = 0.7494). No eye in either group had a pupil diameter of less than 6 mm at any time during the procedure.

Conclusions : No significant differences were identified between Omidria® and epinephrine with regards to maintenance of intraoperative mydriasis. This finding warrants further investigation in prospective randomized studies with larger sample sizes.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×