June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
En Face OCT Analysis to Assess the Spectrum of Perivenular Ischemia and PAMM in Retinal Vascular Occlusion
Author Affiliations & Notes
  • Ananda Kalevar
    West Coast Retina Medical Group, San Francisco, California, United States
    California Pacific Medical Center, San Francisco, California, United States
  • Khalil Ghasami Falavarjani
    David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States
    Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
  • Nopasak Phasukkijwatana
    David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States
    Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
  • Emmett Cunningham
    West Coast Retina Medical Group, San Francisco, California, United States
    California Pacific Medical Center, San Francisco, California, United States
  • Richard McDonald
    West Coast Retina Medical Group, San Francisco, California, United States
  • Rosa Dolz-Marco
    Vitreous Retina Macula Consultants of New York, New York, New York, United States
  • Phillip Roberts
    Medical University of Vienna, Vienna, Austria
  • Irena Tsui
    David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States
  • Richard B Rosen
    New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States
  • K Bailey Freund
    Vitreous Retina Macula Consultants of New York, New York, New York, United States
  • Srinivas R Sadda
    David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States
  • Lee M Jampol
    Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States
  • David Sarraf
    David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States
    Greater Los Angeles VA Healthcare Center, Los Angeles, California, United States
  • Footnotes
    Commercial Relationships   Ananda Kalevar, None; Khalil Falavarjani, None; Nopasak Phasukkijwatana, None; Emmett Cunningham, None; Richard McDonald, None; Rosa Dolz-Marco, None; Phillip Roberts, None; Irena Tsui, None; Richard Rosen, None; K Bailey Freund, None; Srinivas Sadda, None; Lee Jampol, None; David Sarraf, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 1889. doi:
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    • Get Citation

      Ananda Kalevar, Khalil Ghasami Falavarjani, Nopasak Phasukkijwatana, Emmett Cunningham, Richard McDonald, Rosa Dolz-Marco, Phillip Roberts, Irena Tsui, Richard B Rosen, K Bailey Freund, Srinivas R Sadda, Lee M Jampol, David Sarraf; En Face OCT Analysis to Assess the Spectrum of Perivenular Ischemia and PAMM in Retinal Vascular Occlusion. Invest. Ophthalmol. Vis. Sci. 2017;58(8):1889.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess the spectrum of perivenular ischemia in eyes with retinal vein occlusion using en face optical coherence tomography (OCT).

Methods : Eyes with recent retinal vascular occlusion illustrating paracentral acute middle maculopathy (PAMM) in a perivenular pattern with en face OCT were evaluated in this study. Multimodal retinal imaging including en face OCT segmentation of the inner nuclear layer was performed in all patients. Color fundus photography and fluorescein angiography (FA) images were used to create a vascular overlay of the retinal veins versus the retinal arteries to map the distribution of PAMM with en face OCT analysis.

Results : Multimodal retinal imaging was performed in 11 eyes with acute retinal vascular obstruction. While 7 eyes demonstrated obvious findings of retinal vein obstruction (5 with central and 2 with hemicentral retinal vein occlusion), 4 eyes were unremarkable at baseline. One of these 4 eyes progressed to CRVO. En face OCT analysis demonstrated a spectrum of perivenular PAMM illustrating progressive wider perivenular lesions with sparing of the periarteriolar area in all cases.

Conclusions : En face OCT may illustrate a remarkable perivenular pattern of PAMM in eyes with retinal vascular obstruction even in the absence of significant funduscopic findings. Perivenular PAMM with en face OCT demonstrates a wide spectrum of variation that may develop due to outflow obstruction causing perfusion pressure reduction in the affected eye resulting from different severities of retinal vein occlusion.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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