June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Pre- and postcycloplegic refractions in children and adolescents
Author Affiliations & Notes
  • Dan Zhu
    Ophthalmology, The Affiliated Hospital of Inner Mongolia Medical, Hohhot, China
  • Da-Yong Yang
    Ophthalmology, The Affiliated Hospital of Inner Mongolia Medical, Hohhot, China
  • Yan Wang
    Ophthalmology, The Affiliated Hospital of Inner Mongolia Medical, Hohhot, China
  • Footnotes
    Commercial Relationships   Dan Zhu, None; Da-Yong Yang, None; Yan Wang, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 2395. doi:
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      Dan Zhu, Da-Yong Yang, Yan Wang; Pre- and postcycloplegic refractions in children and adolescents
      . Invest. Ophthalmol. Vis. Sci. 2017;58(8):2395.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To determine the difference between cycloplegic and non-cycloplegic refractive error and its associated factors in Chinese children and adolescents with a high prevalence of myopia.

Methods : A school-based study including 1565 students aged 6 to 21 years was conducted in 2013 in Ejina, Inner Mongolia, China. Comprehensive eye examinations were performed. Pre-and postcycloplegic refractive error were measured using an auto-refractor. For cycloplegic refraction, one drop of topical 1.0% cyclopentolate was administered to each eye twice with a 5-minute interval and a third drop was administered 15 minutes after the second drop if the pupil size was less than 6 mm or if the pupillary light reflex was still present.

Results : Two drops of cyclopentolate were found to be sufficient in 59% of the study participants while the other 41% need an additional drop. The prevalence of myopia was 89.5% in participants aged over 12 years and 68.6% in those aged 12 years or younger (P<0.001). When myopia was defined as spherical equivalent (SE) of less than -0.5 diopter (D), the prevalence estimates were 76.7% (95% confidence interval [CI] 74.6-78.8) and 54.1% (95%CI 51.6-56.6) before and after cycloplegic refraction, respectively. When hyperopia was defined as SE of more than 0.5D, the prevalence was only 2.8% (95%CI 1.9-3.6) before cycloplegic refraction while it was 15.5% (95%CI 13.7-17.3) after cycloplegic refraction. Increased difference between cycloplegic and non-cycloplegic refractive error was associated with decreased intraocular pressures (P=0.01).

Conclusions : Lack of cycloplegia in refractive error measurement was associated with significant misclassifications in both myopia and hyperopia among Chinese children and adolescents. Decreased intraocular pressure was related to a greater difference between cycloplegic and non-cycloplegic refractive error.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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