June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
27-gauge vitrectomy wound integrity: a randomized pilot study comparing angled versus straight entry in fluid-filled vitrectomized eyes
Author Affiliations & Notes
  • M. Ali Ali Khan
    Ophthalmology, Doheny Eye Center UCLA, Pasadena, California, United States
    Ophthalmology, Wills Eye Hospital , Philadelphia, Pennsylvania, United States
  • Alia Durrani
    Ophthalmology, Wills Eye Hospital , Philadelphia, Pennsylvania, United States
  • Jason Hsu
    Ophthalmology, Wills Eye Hospital , Philadelphia, Pennsylvania, United States
  • Carl D Regillo
    Ophthalmology, Wills Eye Hospital , Philadelphia, Pennsylvania, United States
  • Footnotes
    Commercial Relationships   M. Ali Khan, None; Alia Durrani, None; Jason Hsu, None; Carl Regillo, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 2791. doi:
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      M. Ali Ali Khan, Alia Durrani, Jason Hsu, Carl D Regillo; 27-gauge vitrectomy wound integrity: a randomized pilot study comparing angled versus straight entry in fluid-filled vitrectomized eyes. Invest. Ophthalmol. Vis. Sci. 2017;58(8):2791.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To compare clinical outcomes using angled versus straight trocar insertion during 27-gauge pars plana vitrectomy (PPV) for epiretinal membrane.

Methods : Pilot randomized controlled trial. 30 eyes of 30 patients undergoing 27-gauge PPV with membrane peeling for epiretinal membrane were randomized 1:1 to receive angled or straight trocar insertion. Intraocular pressure (IOP) and postoperative wound-related complications were compared.

Results : Fifteen eyes were randomized to each the angled and straight incision groups. No significant difference in phakic status (p=0.71) or preoperative IOP (15.1±3.4 versus 14.6±3.0 mm Hg, p=0.67) existed between groups. On post-operative day 1, eyes in the straight group had lower IOP compared to the angled group (11.8±3.9 versus 15.3±5.2 mm Hg, p=0.04) and a relative decrease in IOP compared to preoperative values (11.8±3.9 versus 15.1±3.4 mm Hg, p<0.01). No IOP difference between groups was present at day 7 (p=0.43) or day 30 (p=0.42). Post-operative complications included transient hypotony (1 eye, straight group) and serous choroidal detachment (1 eye, angled group).

Conclusions : Eyes with straight incisions had transiently lower IOP on post-operative day 1, possibly suggestive of subclinical wound leak in the very early post-operative period. Overall, rates of hypotony and sclerotomy-related complications were similarly low between wound construction strategies.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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