June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Central and Peripheral Corneal Thickness Changes during Scleral Contact Lens Wear
Author Affiliations & Notes
  • Vivien Tse
    Clinical Research Center, School of Optometry, University of California, Berkeley, Berkeley, California, United States
  • Young Hyun Kim
    Clinical Research Center, School of Optometry, University of California, Berkeley, Berkeley, California, United States
  • Kristina Lin
    Clinical Research Center, School of Optometry, University of California, Berkeley, Berkeley, California, United States
  • Bo Tan
    Clinical Research Center, School of Optometry, University of California, Berkeley, Berkeley, California, United States
  • Yixiu Zhou
    Clinical Research Center, School of Optometry, University of California, Berkeley, Berkeley, California, United States
  • Wing Li
    Clinical Research Center, School of Optometry, University of California, Berkeley, Berkeley, California, United States
  • Meng C Lin
    Clinical Research Center, School of Optometry, University of California, Berkeley, Berkeley, California, United States
    Vision Science Group, University of California, Berkeley, Berkeley, California, United States
  • Footnotes
    Commercial Relationships   Vivien Tse, Essilor (F); Young Hyun Kim, None; Kristina Lin, None; Bo Tan, None; Yixiu Zhou, None; Wing Li, Essilor (F); Meng Lin, Essilor (F)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 3085. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Vivien Tse, Young Hyun Kim, Kristina Lin, Bo Tan, Yixiu Zhou, Wing Li, Meng C Lin; Central and Peripheral Corneal Thickness Changes during Scleral Contact Lens Wear. Invest. Ophthalmol. Vis. Sci. 2017;58(8):3085.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To evaluate corneal thickness changes in the center and periphery after 5 hours of scleral contact lens wear

Methods : Subjects with no history of contact lens wear in the past 12 months and presenting with no active ocular disease were recruited. Scleral lenses of fluorosilicone acrylate material (hofocon A; 15.6mm diameter; 97 Dk; 1.44 refractive index; average lens thickness of 400 µm) were used. Ocular surface examination with slit lamp biomicroscope was performed before and after 5-hr lens wear. Central, peripheral corneal thicknesses (nasal and temporal quadrants) and central post-lens tear thickness of each eye were measured by high-resolution spectral domain optical coherence tomography (OCT) (ENVISU 2300; Bioptigen Inc.) before and during lens wear, as well as after lens removal. Mixed effect model assigning repeated measurements as random effect was employed to examine the corneal thickness changes from baseline in both center and periphery.

Results : A total of 10 sets of central cornea and 20 sets of peripheral cornea OCT images were analyzed for percent corneal thickness changes (%CTΔ) from 5 subjects (Mean±SD age: 20.2±1.8 years). Central %CTΔ after 5-hr lens wear was 0.8±0.9% (p=0.02) and peripheral %CTΔ were 1.4±0.7% nasally (p=0.62) and 1.4±0.9% temporally (p=0.56). Central %CTΔ reached its peak at 2 hours after lens wear (1.0±0.4%; p=0.003). Mean±SD of central post-lens tear thickness before lens removal was 188.4±99.8µm. Of interest, 40% eyes exhibited signs of microcystic changes of corneal epithelium in the periphery, which showed no qualitative trend with %CTΔ.

Conclusions : Using a novel image processing technique, we were able to monitor peripheral corneal thickness change after scleral lens wear but it was not considered significantly different from baseline. We found a change in central corneal thickness however it may not be considered clinically significant. There was no relationship between corneal thickness changes and the ocular sign of microcystic changes of corneal epithelium.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×