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Muriel Schornack, Cherie B Nau; Change in Fluid Reservoir Density at 20 Minute Intervals Over 2 Hours with 3 Scleral Lens Diameters. Invest. Ophthalmol. Vis. Sci. 2017;58(8):3088.
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© ARVO (1962-2015); The Authors (2016-present)
Clinical observation has suggested that post-lens fluid reservoir turbidity is more pronounced in large than small scleral lenses. This study compares changes in fluid reservoir optical density at 20-minute intervals over 2 hours of wear in scleral lenses of three diameters.
Thirty-five participants, fourteen men and twenty-one women age 20-44 years (29 years, mean[SD]) with no history of eye disease, surgery or previous scleral lens wear, were fitted on one randomized eye with three lenses: 15.0 mm Jupiter (Visionary Optics, Front Royal, VA), 18.0 mm Digiform (Truform Optics, Beford, TX) and18.2-mm Jupiter (Visionary Optics, Front Royal, VA). Lenses were selected from a diagnostic fitting set to provide 200-300 μm clearance between the lens and central cornea immediately after application. Lenses were evaluated at separate visits. Two images of the lens and cornea were recorded by Scheimpflug photography (Pentacam, Oculus, Inc.) immediately after application and at 20-minute intervals for 2 hours. Optical density of the fluid reservoir was assessed midway between the back surface of the lens and the anterior surface of the cornea in all vertical images using the Pentacam’s densitometry analysis software. The average value of two images for each time was recorded. Densitometry values with all three lens designs were compared using Repeated measures analysis of variance. Significant differences were investigated between lens sizes using the Student-Newman-Keuls (SNK) procedure.
Initial optical density was 4.9[1.1]%15 mm; 4.5[0.4]%18 mm; and 4.9[0.7]% 18.2 mm; SNK procedure shows a difference between 18 mm and other two lenses (p=.019), but no difference between 15 and 18.2 mm lenses. At 20 minutes, optical density was 7.0[2.0]%15 mm; 6.1[1.2]% 18 mm; 6.5[1.8]% 18.2 mm. SNK procedure shows difference between 18 mm and other two lenses (p=0.027), but no difference between 15 and 18.2 mm lenses. At 40 minutes, optical density was 8.0[2.8]% 15 mm; 6.9[1.9]% 18 mm; and 7.6[2.4]% 18.2 mm. SNK procedure shows difference between 15 and 18 mm lenses (p=.038), but no other differences were noted. No differences were noted at any other time points.
Optical density of the post-lens fluid reservoir increases during two hour of continuous wear of 15, 18, and 18.2 mm scleral lenses. Lens diameter does not appear to affect the rate of fluid reservoir optical density change.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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