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hanan mofty, alzahrani khaled, Fiona Carley, sophie harper, Arun Brahma, Debbie Morley, M Chantal Hillarby; Evaluation of corneal symmetry after UV corneal crosslinking for keratoconus. Invest. Ophthalmol. Vis. Sci. 2017;58(8):3521.
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To assess UV corneal crosslinking (CXL) treatment for keratoconus by evaluating the corneal regularity through patients’ follow-up using Oculus Pentacam. This could provide relevant information about secondary haze which is commonly present treatment.
: A total of eighteen eyes from eighteen CXL keratoconic patients were studied before and after treatment and six eyes from six keratoconic patients, who were not treated with CXL were used as controls. Treated patients were seen at 1-3 months, 4-6 months, 7-9 months, 10-12 months afetr treatment and analysis was compared to an untreated baseline. Symmetry and asphericity were evaluated and correlated with BCVA and with maximum k-readings.
In the CXL treated group, there were significant changes in the ISV and KI at 3 months after treatment and in IHA and Rmin at 9 months after treatment. After one year, all indices show no significant changes from the baseline but there were significant changes in ISV, KI, CKI and Rmin in the untreated group. A novel finding in our study was a slight positive shift of anterior asphericity in 6mm, 7mm and 8mm three months after treatment which had a correlation with BCVA (R2= 0.390, P=0.05) and strong correlation with maximum k-reading (R2= 0.690, P=0.005).
transient corneal haze is associated with the spherical aberration influenced by temporal evolution of surface ablation and increases of cloudiness. However, Insignificant changes in symmetry readings after one year leads to support the idea that CXL stabilizes the cornea structure and normalizes corneal shape postoperatively when compared to untreated patients.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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