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Naim Terai, Robert Herber, Lisa Ramm, Eberhard Spoerl, Lutz E Pillunat; Assessment of biomechanical properties using Scheimpflug imaging in keratoconus patients. Invest. Ophthalmol. Vis. Sci. 2017;58(8):4313.
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© ARVO (1962-2015); The Authors (2016-present)
Corneal Visualization Scheimpflug technology (CorVis ST) should allow non-contact measurement of corneal biomechanical parameters. The aim of the present study was to investigate new corneal deformation response parameters in keratoconic eyes using CorVis and to compare these data to healthy subjects.
Ninety-two keratoconic eyes were examined using corneal visualization Scheimpflug technology (Corvis ST). Biomechanical parameters were compared to a normative data base of Corvis ST. Biomechanical corrected IOP (bIOP), Stiffness parameter (SP-A1), Ratio of deformation amplitude (DARatio-2mm; DA-Ratio-1mm), Ambrosio related thickness (Arth), Integrated radius (IntR) and Corneal biomechanical index (CBI) were measured. Statistical analysis with unpaired t-test was performed (SPSS 23.0).
Ninety-two keratoconic eyes were included. Mean age of all patients was 37.8 years (range: 21 - 65 yrs). Following parameters were measured: Mean DA Ratio-2mm was 5.7 ± 1.8. Mean DA Ratio Max-1mm was 1.7 ± 0.1. Arth was 297.9 ± 188.3. IntR was 11.6 ± 3.1 and SP A1 was 82.4 ± 25.0. These five parameters were statistically significantly different from healthy corneas (p < 0.0001). All other parameters (blOP, CBI) did not show a statistical significant difference.
The new corneal deformation parameters by the Corvis ST provide useful information for the study of ocular biomechanics in keratoconus patients. Most of the analyzed new ocular biomechanical parameters were significantly different between keratoconic and normal eyes. Further research is needed to develop more comprehensive clinical applications with these new ocular biomechanical parameters.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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