June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Ten-year change of refractive error, anterior chamber depth and axial length in southern Chinese children
Author Affiliations & Notes
  • Zhixi Li
    prevention of blindness, Zhongshan Ophthalmic Center,Sun Yat-sen University, Guangzhou, China
  • Zhuoting Zhu
    prevention of blindness, Zhongshan Ophthalmic Center,Sun Yat-sen University, Guangzhou, China
  • Xiaohu Ding
    prevention of blindness, Zhongshan Ophthalmic Center,Sun Yat-sen University, Guangzhou, China
  • Mingguang He
    prevention of blindness, Zhongshan Ophthalmic Center,Sun Yat-sen University, Guangzhou, China
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia
  • Footnotes
    Commercial Relationships   Zhixi Li, None; Zhuoting Zhu, None; Xiaohu Ding, None; Mingguang He, None
  • Footnotes
    Support  Fundamental Research Funds of the State Key Laboratory in Ophthalmology, National Natural Science Foundation of China 81125007, Science and Technology Planning Project of Guangdong Province, China 2013B20400003
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 4425. doi:
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    • Get Citation

      Zhixi Li, Zhuoting Zhu, Xiaohu Ding, Mingguang He; Ten-year change of refractive error, anterior chamber depth and axial length in southern Chinese children. Invest. Ophthalmol. Vis. Sci. 2017;58(8):4425.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate changes in refractive errors (REs), anterior chamber depth (ACD) and axial length (AL) among southern Chinese children over a ten year period.

Methods : The first-born twins aged 7 to 15 years old in baseline (2006) from Guangzhou Twin Eye Study with annually visits from 2006 to 2016 were included in this study. Children underwent noninvasive partial-coherence laser interferometry (IOLMaster) before pupil dilation and cycloplegic autorefraction .

Results : A total of 637 participants s underwent comprehensive examinations from 2006 to 2016 (2006 mean [SD] age, 10.66 [2.3] years; 51.3% female). In the longitudinal data, linear mixed models were used to explore changes in outcomes over time. Myopic SE (P<.001) and AL (P<.001) increased at 0.29 diopter/y (95% CI, 0.28 to 0.29) and 0.16 mm/y (95% CI, 0.16 to 0.18) respectively. And females were more likely to get more myopic and longer axial length than males (both P<0.001).There was no significant change of ACD over the follow up period (0.246).

Conclusions : This study show that the important longitudinal changes of RE, ACD and AL in southern Chinese children and myopia is very prevalent among Chinese children.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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