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Itaru Kimura, Hiroto Kuroda, Masayuki Suzuki, Hisashi Ibuki, Takuhei Shoji, Kei Shinoda, Makoto Araie, Shin Yoneya; Ellipsoid zone thickness measurements by high resolution mode-locked laser optical coherence tomogramphy in healthy eyes. Invest. Ophthalmol. Vis. Sci. 2017;58(8):4815.
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© ARVO (1962-2015); The Authors (2016-present)
Ellipsoid zone (EZ) thickness has been measured by means of optical coherence tomography (OCT) technique. We measured EZ thickness obtained by high resolution mode-locked laser OCT in healthy eyes.
In 31 eyes of 16 healthy subjects (12 males and 4 females with an average age of 33.3±7.3 y/o), longitudinal reflectance profile (LRP) was produced by measurements of luminance at 5 points (foveola, 0.5mm, 1.0mm nasal, or temporal from the foveola) in A-scans. Full width at 75% maximum in LRP was defined as EZ thickness. We developed the OCT system using an ultra-broadband Kerr lens mode-locked Ti:Sapphire laser and a wideband spectrometer. The spectral bandwidth of the light source was 200 nm full-width at half maximum at a central wavelength of 840 nm. A high-speed CCD camera with 2048×300 pixels (Basler, Ahrensburg, Germany) was used as the detection system. The measurement speed was 50,000 depth-scans/s, and depth resolution was measured to be less than 2.0 µm into the tissue (Kuroda H, et al, Applied Physics Letters 2013).
The averaged EZ thickness values at 1.0mm, 0.5mm temporal from foveola, foveola, 0.5mm, 1.0mm nasal from foveola were 15.6±6.2μm, 16.5±5.2μm, 14.1±5.4μm, 17.2±7.2μm, 17.4±7.0μm, respectively. This result was almost equal to the report by Matsui, et al, using ultrahigh resolution SD-OCT (16.8±1.8μm,16.7±2.3μm,16.5±2.7μm,15.9±2.4μm,16.7±2.8μm,respecitively. Japanese Retina & Vitreous Society, Japanese Society for Ocular Circulation Joint Meeting 2015).
Ellipsoid zone thickness measurements by high resolution mode-locked laser OCT don’t coincide with measurements by conventional SD-OCT, but coincide with those by ultrahigh resolution SD-OCT.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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