June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Three-Month Outcomes from a Prospective, Randomized, Contralateral, Eye-to-Eye Comparison of Wavefront-Guided and Wavefront-Optimized PRK in Myopes
Author Affiliations & Notes
  • Ryan Smith
    Ophthalmology , Stanford University, Los Altos, California, United States
  • Edward E Manche
    Ophthalmology , Stanford University, Los Altos, California, United States
  • Footnotes
    Commercial Relationships   Ryan Smith, None; Edward Manche, Abbott Medical Optics, Inc. (C), Allergan, Inc. (C), Avellino Laboratories, Inc. (C), Calhoun Vision, Inc. (I), Carl Zeiss Meditec, Inc. (C), Guidepoint Global, Inc. (C), Seros Medical, LLC. (I), Seros Medical, LLC. (P), Veralas, Inc. (I)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 5283. doi:
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      Ryan Smith, Edward E Manche; Three-Month Outcomes from a Prospective, Randomized, Contralateral, Eye-to-Eye Comparison of Wavefront-Guided and Wavefront-Optimized PRK in Myopes. Invest. Ophthalmol. Vis. Sci. 2017;58(8):5283.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To compare wavefront WF-optimized and WF-guided PRK in myopic patients.

Methods : Forty eyes from 20 participants were prospectively randomized to receive either WF-optimized or WF-guided PRK with the WaveLight Allegretto Eye-Q 400-Hz excimer laser (Alcon, Inc., Hüenberg, Switzerland). One eye was randomized to recieve WF-guided PRK and the fellow eye was randomized to receive WF-optimized PRK. Eyes were randomized according to ocular dominance. Main outcome measures included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), <5% and <525% contrast sensitivity, and WF aberrometry data. Postoperative measurements were analyzed at three months.

Results : The frequency with which the WF-optimized and WF-guided group attained a refractive error within ±0.25 diopters of emmetropia was not significantly different between groups (p >0.05). Furthermore, the frequency with which the WF-guided and WF-optimized groups achieved postoperative UDVA of ≥20/16 or ≥20/20 and the frequency with which the groups lost 1 or 2 or more lines or maintained their preoperative CDVA were not statistically different from each other (all P >0.05). There were no statistically significant differences in UDVA, CDVA, contrast sensitivity, astigmatism, coma, trefoil, or higher-order root mean square error between the groups (all P >0.05).

Conclusions : Wavefront-optimized and Wavefront-guided PRK using the Alcon WaveLight Allegretto Eye-Q 400-Hz excimer laser platform provide similar results in myopic patients at 3 months post operative follow-up.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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