June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Continuous Intraocular Pressure monitoring in patients with Obstructive Sleep Apnea Syndrome (OSAS) using Sensimed TriggerfishTM
Author Affiliations & Notes
  • Elena M Carnero
    Ophthalmology, Clinica Universidad de Navarra, Pamplona, Navarra, Spain
  • Elena Urrestarazu
    Neurophisiology , Clinica Universidad de Navarra, Pamplona, Navarra, Spain
  • Estefania Rivas-Navas
    Neurophisiology , Clinica Universidad de Navarra, Pamplona, Navarra, Spain
  • Vicente Polo
    Ophthalmology, Hospital Miguel Servet, Zaragoza, Aragón, Spain
  • Jose Manuel Larrosa
    Ophthalmology, Hospital Miguel Servet, Zaragoza, Aragón, Spain
  • Vanesa Antón
    Ophthalmology, Clinica Universidad de Navarra, Pamplona, Navarra, Spain
  • Adriano Guarnieri
    Ophthalmology, Clinica Universidad de Navarra, Pamplona, Navarra, Spain
  • Javier Moreno-Montanes
    Ophthalmology, Clinica Universidad de Navarra, Pamplona, Navarra, Spain
  • Footnotes
    Commercial Relationships   Elena Carnero, None; Elena Urrestarazu, None; Estefania Rivas-Navas, None; Vicente Polo, None; Jose Manuel Larrosa, None; Vanesa Antón, None; Adriano Guarnieri, None; Javier Moreno-Montanes, Alcon (F), Allergan (F), Sylentis (C), Thea (F)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 5330. doi:
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      Elena M Carnero, Elena Urrestarazu, Estefania Rivas-Navas, Vicente Polo, Jose Manuel Larrosa, Vanesa Antón, Adriano Guarnieri, Javier Moreno-Montanes; Continuous Intraocular Pressure monitoring in patients with Obstructive Sleep Apnea Syndrome (OSAS) using Sensimed TriggerfishTM. Invest. Ophthalmol. Vis. Sci. 2017;58(8):5330.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The purpose of this study is analyze the variations of the nocturnal Intraocular Pressure (IOP) in patients with Obstructive Sleep Apnea Syndrome (OSAS) using the Sensimed TrigerfishTM contact lens sensor (CLS).

Methods : Eleven OSAS patients who had no ocular diseases were recruited in this prospective study. The subjects underwent IOP monitoring in one eye (30 seconds every five minutes) while the polysomnographic data was recorded at the sleep disorders unit. The patients were classified according to the Apnea–Hypopnea Index (AHI) into severe (AHI>30 ), moderate (15-30) and mild OSAS (AHI<15). Also, the respiratory event related arousal index was evaluated. Nonparametric correlation tests was used in the SPSS software.

Results : All the patients showed a significant increase in the IOP at nocturnal time compared to diurnal measures resulting in a “Wake-to-sleep slope” (WSS). This increase in the IOP is followed by a variable plateau time (Plateau Duration) where the IOP showed small variations. The current study found a positive correlation between the plateau duration and the severity of the OSAS (r=0.728 p=0.011) or the total number of apnea-hypopneas (r=0.718 p=0.013). Moreover, a positive correlation between the WSS and plateau duration (r=0.621 p=0.041) was observed. RERA, a parameter related to the severity to the OSAS, also showed a positive correlation with the duration of the IOP plateau (r=0,674 p=0,023).

Conclusions : This study evaluated 11 patients with different degrees of OSAS and found a positive correlation between severity of the OSAS and the IOP plateau time. Also the increased IOP was related to other polysomnographic data. These results suggest that OSAS influences the IOP during the nocturnal period.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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