June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Endophthalmitis and Concurrent or Delayed-onset Rhegmatogenous Retinal Detachment managed with Silicone Oil
Author Affiliations & Notes
  • Avinash Pathengay
    LV Prasad Eye Institute, Visakhapatnam, India
  • Vivek Dave
    LV Prasad Eye Institute, Visakhapatnam, India
  • Nidhi Relhan
    Bascom Palmer Eye Institute, Miami, Florida, United States
  • Rajeev Pappuru
    LV Prasad Eye Institute, Visakhapatnam, India
  • Harry W Flynn
    Bascom Palmer Eye Institute, Miami, Florida, United States
  • Taraprasad Das
    LV Prasad Eye Institute, Visakhapatnam, India
  • Footnotes
    Commercial Relationships   Avinash Pathengay, None; Vivek Dave, None; Nidhi Relhan, None; Rajeev Pappuru, None; Harry Flynn, None; Taraprasad Das, None
  • Footnotes
    Support  Hyderabad Eye Institute
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 5508. doi:
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      Avinash Pathengay, Vivek Dave, Nidhi Relhan, Rajeev Pappuru, Harry W Flynn, Taraprasad Das; Endophthalmitis and Concurrent or Delayed-onset Rhegmatogenous Retinal Detachment managed with Silicone Oil. Invest. Ophthalmol. Vis. Sci. 2017;58(8):5508.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Management outcomes of retinal detachment in the setting of endophthalmitis using silicone oil tamponade are not well described. We performed a retrospective observational study to describe the demographics, clinical presentations, anatomic and visual outcomes of endophthalmitis with con-current or delayed onset retinal detachment managed with silicone oil injection.

Methods : The patient database in the Medical Records Department with diagnosis code “endophthalmitis” and "rhegmatogenous retinal detachment" over a time period between January 1990 and December 2014 was identified. The patients were classified in group 1 – patients having RD at presentation (Concurrent RD group) and group 2 – patients developing RD during follow up (Delayed-onset RD group). All patients received silicone oil for the management of retinal detachment immediately or during follow-up . Anatomical success was defined as retina attached completely at the last visit. Functional success was defined as the best corrected visual acuity of 20/400 or better at the last visit. The data was analyzed using MedCalc ver 12.2.1.0 statistical software. A p value of <0.05 was assigned as statistically significant.

Results : A total of 93 patients were included in the current study. The table below describes the outcomes.
Group 1 – N=20 patients
(Concurrent RD) (21.5%)
Group 2 – N=73 patients
(Delayed-onset RD) (78.5%)
p value
Initial Treatment
Vitreous tap + IOAB
PPV + IOAB
PPV + IOAB + SOI
None
1/20 (5%)
19/20 (95%)
14/73 (19.2%)
55/73 (75.3%)
4/73 (5.5%)
PPV + SOI (during follow-up)
1/20
73/73
<0.0001
Recurrent RD
7/20
22/73
0.88
SOR
9/20
35/73
0.9
Anatomical Successa
(Complete retinal attachment at 4 months)
14/19* (73.7%)
66/67** (98.5%)
0.001
Functional Successb
(Visual acuity ≥ 20/400 at 4 months)
6/20 (30%)
29/73 (39.7%)
0.59
Follow-up duration (months)
36.8±53.7
(range 4- 168)
22.6±31.6
(range 4-180)
0.13
a-p value=, b-p value=, *data available for 19 patients, **data available for 67 patients, RD-retinal detachment, IOAB – intravitreal antibiotics, PPV – pars plana vitrectomy, SOI – silicone oil injection

Conclusions : Retinal detachment associated with endophthalmitis is associated with poor anatomic and visual outcomes especially in the concurrent presentation.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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