June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Combined Conjunctival Autograft Transplantation (CAT) and Overlay Amniotic Membrane Transplantation (AMT) Has Better Clinical Outcome in Primary and Recurrent Pterygium Surgery versus CAT or AMT Alone.
Author Affiliations & Notes
  • Tejsu Malla
    Ophthalmology, Zhongda hospital, Southeast University, Nanjing, China
  • Kai Hu
    Ophthalmology, Drum Tower Hospital, Nanjing University Medical School, Nanjing, China
  • Footnotes
    Commercial Relationships   Tejsu Malla, None; Kai Hu, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 5695. doi:
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      Tejsu Malla, Kai Hu; Combined Conjunctival Autograft Transplantation (CAT) and Overlay Amniotic Membrane Transplantation (AMT) Has Better Clinical Outcome in Primary and Recurrent Pterygium Surgery versus CAT or AMT Alone.. Invest. Ophthalmol. Vis. Sci. 2017;58(8):5695.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To compare the long-term outcome of primary and recurrent pterygium surgery with three different techniques as followed: combined conjunctival autograft and overlay Amniotic membrane transplantation (AMT with CAT), Conjunctival autograft transplantation (CAT) only and amniotic membrane transplantation (AMT) only.

Methods : In this Retrospective study, 108 (81 primary, 27 recurrent) pterygium patients seen in Zhongda hospital in Nanjing of China from July 2013 to July 2015 were enrolled, who underwent CAT (Group A), AMT (Group B) or AMT with CAT (Group C) respectively. Each group has 27 primary and 9 recurrent cases (n=36). Those were compared based on the surgery effect, recurrences and post operative complications. Chi square and Fisher's exact tests were used for statistical analysis.

Results : The recurrence cases post surgery were 5 (13.88%)(4 from primary, 1 from recurrent; the same description below), 10 (27.77%) (4, 6) and 1 (2.7%)(1, 0) in groups A, B, and C respectively; dry eye occurrence cases were 17 (47.22 %)(14, 3), 22 (61.11 %) (16, 6) and 5 (13.88 %) (3, 2) respectively. Conjuctival inflammation occurrence cases were 21 (58.33%)(13, 8), 17 (47.22%)(10, 7) and 5 (13.88 %)(2, 3) respectively. Patients in Group C (either primary or recurrent or both) showed significantly better results than those in Group A or B ( P<0.05) regarding above-mentioned clinical effects.

Conclusions : The use of combined CAT and overly AMT has significantly lower long-term rates of recurrence and post operative complications for primary and recurrent pterygium excision surgery than using single graft surgery (Either CAT or AMT ).

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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