June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Baseline intraocular pressure more strongly correlates with decreased visual function in open angle glaucoma patients with diabetes mellitus over 4 years
Author Affiliations & Notes
  • Katherine Hutchins
    Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States
  • Alon Harris
    Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States
  • Alice Chandra Verticchio Vercellin
    University Eye Clinic, IRCCS Policlinico San Matteo, Pavia, Italy
  • Josh C Gross
    Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States
  • Colin Ridenour
    Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States
  • Ingrida Januleviciene
    Ophthalmology, Lithuanian University of Health Sciences, Kaunas, Lithuania
  • June Geng
    Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States
  • Brent A Siesky
    Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States
  • Footnotes
    Commercial Relationships   Katherine Hutchins, None; Alon Harris, AdOM (C), AdOM (I), Biolight (C), Isarna Therapeutics (C), Nano Retina (C), Nano Retina (I), Ono Pharmaceuticals (C), Oxymap (I), ScienceBased Health (C), Stemnion (C); Alice Chandra Verticchio Vercellin, None; Josh Gross, None; Colin Ridenour, None; Ingrida Januleviciene, Alcon (C), Alcon (R), Allergan (C), Allergan (R), Origmed (C), Origmed (R), Santen (C), Santen (R), Vittamed (C), Vittamed (R); June Geng, None; Brent Siesky, None
  • Footnotes
    Support  American Diabetes Association Grant 1-12-IN-20; Research to Prevent Blindness NY, NY
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 5841. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Katherine Hutchins, Alon Harris, Alice Chandra Verticchio Vercellin, Josh C Gross, Colin Ridenour, Ingrida Januleviciene, June Geng, Brent A Siesky; Baseline intraocular pressure more strongly correlates with decreased visual function in open angle glaucoma patients with diabetes mellitus over 4 years. Invest. Ophthalmol. Vis. Sci. 2017;58(8):5841.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To examine the relationship between baseline intraocular pressure (IOP) and visual function in open angle glaucoma (OAG) patients with diabetes mellitus (DM) over 4 years.

Methods : 85 patients with OAG (16 with DM, 69 without DM) were evaluated at baseline for IOP using Goldmann applanation tonometry and for visual function by 24-2 Swedish interactive threshold algorithm visual field (VF) (Humphrey) every 6 months for 4 years. Functional progression was defined as 2 consecutive visits with mean deviation (MD) decrease by at least 2 compared to baseline and/or advanced glaucoma intervention study (AGIS) increase by at least 2 compared to baseline. Pearson correlations were used to test for associations between measurements, with p<0.05 considered statistically significant.

Results : In OAG patients with and without DM, baseline IOP (mmHg) was 17.08 (95% CI=14.82, 19.34) and 16.27 (15.01, 17.53), respectively. In OAG patients with DM, baseline IOP was negatively and significantly correlated with changes in AGIS score (r=-0.56, p=0.02). In non-DM patients, this relationship was weakly positive and insignificant (r=0.02, p=0.84), leading to significant differences between groups (p=0.03).

Conclusions : Baseline IOP was associated with functional progression differently in OAG patients with DM compared to non-DM OAG patients over 4 years.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×