June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Choriocapillaris and outer choroid blood flow in acute central serous chorioretinopathy: a swept source OCT angiography study
Author Affiliations & Notes
  • Paolo Lanzetta
    Dept of Medical and Biological Sciences - Ophthalmology, University of Udine, Udine, Italy
    Istituto Europeo di Microchirurgia Oculare (IEMO), Udine, Italy
  • Valentina Sarao
    Dept of Medical and Biological Sciences - Ophthalmology, University of Udine, Udine, Italy
    Istituto Europeo di Microchirurgia Oculare (IEMO), Udine, Italy
  • Daniele Veritti
    Dept of Medical and Biological Sciences - Ophthalmology, University of Udine, Udine, Italy
    Istituto Europeo di Microchirurgia Oculare (IEMO), Udine, Italy
  • Footnotes
    Commercial Relationships   Paolo Lanzetta, Alcon (C), Alimera (C), Allergan (C), Bausch&Lomb (C), Bayer (C), Boeringher (C), Centervue (C), Genentech (C), Iridex (P), Lupin (C), Lutronic (C), Novartis (C), Roche (C), Teva (C), Topcon (C); Valentina Sarao, None; Daniele Veritti, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 5933. doi:
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      Paolo Lanzetta, Valentina Sarao, Daniele Veritti; Choriocapillaris and outer choroid blood flow in acute central serous chorioretinopathy: a swept source OCT angiography study. Invest. Ophthalmol. Vis. Sci. 2017;58(8):5933.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate the choriocapillaris and outer choroid blood flow in acute and resolved central serous chorioretinopathy (CSC) by the means of flow density index using swept source optical coherence tomography (SS-OCT) angiography.

Methods : A series of consecutive patients diagnosed with acute CSC underwent conventional SS-OCT and SS-OCT angiography (Triton, Topcon, Japan) during the acute phase and after resolution of the neuroretinal detachment. Controlateral healthy eyes were also evaluated. OCT angiography images were acquired and manually segmented in order to compare the same frames at baseline and after resolution. In order to avoid the OCT angiography attenuation due to the presence of subretinal fluid, we analyzed areas located outside the region involved by the neuroretinal detachment.

Results : Thirteen eyes of 11 patients were enrolled. Nine healthy controlateral eyes were also evaluated. Gradable and high-quality images were available in all cases. At choriocapillaris level the mean (±SD) flow density index was 96.3 ±15.2 during the acute CSC and 95.7 ±11.7 after resolution of neuroretinal detachment (the difference was not statistically significant). In controlateral healthy eyes the density index was 92.3 ±10.2. The mean (±SD) flow density index at level of the outer choroid was 39.6 ±20.4, 79.6 ±15.3 and 75.4 ±12.7 in acute, resolved CSC and controlateral eyes, respectively (p<0.05).

Conclusions : These results suggest that blood flow in the outer choroid is impaired during the acute phase of CSC compared to the values obtained after resolution of the neuroretinal detachment and in controlateral eyes.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.

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