Changes in corneal power and anterior chamber depth found in different animal models with experimentally induced myopia. The x- and y-axis parameters represent either interocular difference (treated eye − fellow control eye) or intergroup differences (treated group − normal group). The
filled and
open symbols represent statistically significant and insignificant changes, respectively.
Gray symbols indicate studies that did not perform statistical tests.
Numbers inside or near each
symbol represent different studies. █ Chicks: (1) Wallman et al.,
72 diffusers; (2) Gottlieb et al.,
137 diffusers; (3) Hayes et al.,
820 diffusers; (4) Irving et al.,
194 lenses; (5) Troilo et al.,
160 diffusers; (6) Napper et al.,
162 diffusers; (7) Napper et al.,
556 diffusers; ⧫ tree shrews: (8) Guggenheim et al.,
802 diffusers; (9) Siegwart et al.,
129 diffusers; (10) McBrien et al.,
271 lid-suture; ▴ guinea pigs: (11) Howlett et al.,
36 diffusers; ▾ marmosets: (12) Graham and Judge,
202 negative lenses; (13) Troilo and Nickla,
347 diffusers; • rhesus monkeys: (14) Smith and Hung,
157 diffusers; (15) Qiao-Grider et al.,
176 diffusers; and (16) Qiao-Grider et al.,
163 diffusers and negative lenses, induced myopia was not available, myopic anisometropia of more than −1.0 D was used. For chicks, the corneal radius of curvature values was converted to corneal powers using a refractive index of n' = 1.369.
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