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Anatomy and Pathology/Oncology

Increasing Incidence of Ophthalmic Lymphoma in Denmark from 1980 to 2005 Free
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Lene D. Sjö; Elisabeth Ralfkiaer; Jan U. Prause; Jorgen H. Petersen; Jakob Madsen; Niels T. Pedersen; Steffen Heegaard
Tags: denmark, eye, incidence, lymphoma
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3283-3288. doi:https://doi.org/10.1167/iovs.08-1768
Change in Embryonic Eye Size and Retinal Cell Proliferation following Intravitreal Injection of Glycosaminoglycans Free
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Willi Halfter
Tags: eye, embryo, intravitreal injections, glycosaminoglycans, heparin
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3289-3298. doi:https://doi.org/10.1167/iovs.07-1421

Biochemistry and Molecular Biology

Mitochondrial Oxidative DNA Damage in Experimental Autoimmune Uveitis Free
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Rahul N. Khurana; Jignesh G. Parikh; Sindhu Saraswathy; Guey-Shuang Wu; Narsing A. Rao
Tags: autoimmune diseases, autoimmunity, dna damage, mitochondria, uveitis
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3299-3304. doi:https://doi.org/10.1167/iovs.07-1607
Curcumin Modulates SDF-1α/CXCR4–Induced Migration of Human Retinal Endothelial Cells (HRECs) Free
PDF
Zaheer Sameermahmood; Muthuswamy Balasubramanyam; Thangavel Saravanan; Mohan Rema
Tags: curcumin, cxcr4 receptors, endothelial cells, western blotting, proto-oncogene proteins c-akt
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3305-3311. doi:https://doi.org/10.1167/iovs.07-0456
Multiple Gene Polymorphisms in the Complement Factor H Gene Are Associated with Exudative Age-Related Macular Degeneration in Chinese Free
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Tsz Kin Ng; Li Jia Chen; David T. L. Liu; Pancy O. S. Tam; Wai Man Chan; Ke Liu; Yi Jun Hu; Kelvin K. L. Chong; Charles S. L. Lau; Sylvia W. Y. Chiang; Dennis S. C. Lam; Chi Pui Pang
Tags: chinese (other dialects), chinese people, complement factor h, exudative age-related macular degeneration, genes
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3312-3317. doi:https://doi.org/10.1167/iovs.07-1517

Clinical and Epidemiologic Research

Assessment of the Effect of Visual Impairment on Mortality through Multiple Health Pathways: Structural Equation Modeling Free
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Sharon L. Christ; David J. Lee; Byron L. Lam; D. Diane Zheng; Kristopher L. Arheart
Tags: disability, health, mortality, visual impairment
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3318-3323. doi:https://doi.org/10.1167/iovs.08-1676
Adult-Onset Myopia: The Genes in Myopia (GEM) Twin Study Free
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Mohamed Dirani; Sri N. Shekar; Paul N. Baird
Tags: adult, myopia, twin studies, genes, twins
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3324-3327. doi:https://doi.org/10.1167/iovs.07-1498
Blood Levels of Vitamin C, Carotenoids and Retinol Are Inversely Associated with Cataract in a North Indian Population Free
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Mukesh Dherani; Gudlavalleti V. S. Murthy; Sanjeev K. Gupta; Ian S. Young; Giovanni Maraini; Monica Camparini; Gill M. Price; Neena John; Usha Chakravarthy; Astrid E. Fletcher
Tags: ascorbic acid, carotenoids, cataract, vitamin a, antioxidants
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3328-3335. doi:https://doi.org/10.1167/iovs.07-1202

Cornea

Cytokine, Chemokine, and Adhesion Molecule Expression Mediated by MAPKs in Human Corneal Fibroblasts Exposed to Poly(I:C) Free
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Yang Liu; Kazuhiro Kimura; Ryoji Yanai; Tai-ichiro Chikama; Teruo Nishida
Tags: cell adhesion molecules, chemokines, cornea, cytokine, fibroblasts
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3336-3344. doi:https://doi.org/10.1167/iovs.07-0972
Epithelial Thickness Changes from the Induction of Myopia with CRTH RGP Contact Lenses Free
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Sameena Haque; Desmond Fonn; Trefford Simpson; Lyndon Jones
Tags: cornea, epithelium, eye, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3345-3350. doi:https://doi.org/10.1167/iovs.07-1596
ERK/p44p42 Mitogen-Activated Protein Kinase Mediates EGF-Stimulated Proliferation of Conjunctival Goblet Cells in Culture Free
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Marie A. Shatos; Jian Gu; Robin R. Hodges; Kameran Lashkari; Darlene A. Dartt
Tags: conjunctiva, goblet cells, epidermal growth factor receptors, mitogen-activated protein kinases
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3351-3359. doi:https://doi.org/10.1167/iovs.08-1677
Identification of Candidate Klf4 Target Genes Reveals the Molecular Basis of the Diverse Regulatory Roles of Klf4 in the Mouse Cornea Free
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Shivalingappa K. Swamynathan; Janine Davis; Joram Piatigorsky
Tags: cornea, genes, mice, candidate disease gene, regulation
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3360-3370. doi:https://doi.org/10.1167/iovs.08-1811
Effect of Soft Contact Lenses on Optical Measurements of Axial Length and Keratometry for Biometry in Eyes with Corneal Irregularities Free
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Jennifer R. Lewis; Andrea E. Knellinger; Ashraf M. Mahmoud; Thomas F. Mauger
Tags: biometry, contact lenses, contact lenses, hydrophilic, cornea, eye
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3371-3378. doi:https://doi.org/10.1167/iovs.07-1247
Heme Oxygenase-1 Induction Attenuates Corneal Inflammation and Accelerates Wound Healing after Epithelial Injury Free
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Kiran Patil; Lars Bellner; Giuseppe Cullaro; Katherine H. Gotlinger; Michael W. Dunn; Michal Laniado Schwartzman
Tags: cornea, epithelium, heme, keratitis, oxygenases
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3379-3386. doi:https://doi.org/10.1167/iovs.07-1515
Stat6-Independent Tissue Inflammation Occurs Selectively on the Ocular Surface and Perioral Skin of IκBζ−/− Mice Free
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Mayumi Ueta; Junji Hamuro; Eiichiro Ueda; Norito Katoh; Masahiro Yamamoto; Kiyoshi Takeda; Shizuo Akira; Shigeru Kinoshita
Tags: body tissue, inflammation, mice, perioral region, skin
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3387-3394. doi:https://doi.org/10.1167/iovs.08-1691
Targeted Cornea Limbal Stem/Progenitor Cell Transfection in an Organ Culture Model Free
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Bojun Zhao; Sarah L. Allinson; Aihua Ma; Adam J. Bentley; Francis L. Martin; Nigel J. Fullwood
Tags: cornea, organ culture techniques, stem cells, transfection, epithelium
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3395-3401. doi:https://doi.org/10.1167/iovs.07-1263
Antimicrobial Efficacy of Riboflavin/UVA Combination (365 nm) In Vitro for Bacterial and Fungal Isolates: A Potential New Treatment for Infectious Keratitis Free
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Suy Anne R. Martins; Juan Castro Combs; Guillermo Noguera; Walter Camacho; Priscila Wittmann; Rhonda Walther; Marisol Cano; James Dick; Ashley Behrens
Tags: antimicrobials, keratitis, riboflavin, ultraviolet a radiation
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3402-3408. doi:https://doi.org/10.1167/iovs.07-1592
In Vivo Laser Scanning Confocal Microscopy Confirms that the Human Corneal Sub-basal Nerve Plexus Is a Highly Dynamic Structure Free
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Dipika V. Patel; Charles N. J. McGhee
Tags: cornea, microscopy, confocal scanning laser, neurons
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3409-3412. doi:https://doi.org/10.1167/iovs.08-1951

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Wavelet Analysis in Infantile Nystagmus Syndrome: Limitations and Abilities Free
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Larry A. Abel; Zhong I. Wang; Louis F. Dell'Osso
Tags: pathologic nystagmus, syndrome, waveforms, tenotomy, inattention
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3413-3423. doi:https://doi.org/10.1167/iovs.08-1710
Factors Influencing the Experience of Oscillopsia in Infantile Nystagmus Syndrome Free
PDF
Kwang M. Cham; Andrew J. Anderson; Larry A. Abel
Tags: oscillopsia, pathologic nystagmus, syndrome, questionnaires, perception
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3424-3431. doi:https://doi.org/10.1167/iovs.08-1709
Timing of Surgery for Infantile Esotropia in Humans: Effects on Cortical Motion Visual Evoked Responses Free
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Christina Gerth; Giuseppe Mirabella; Xiaoqing Li; Thomas Wright; Carol Westall; Linda Colpa; Agnes M. F. Wong
Tags: evoked potentials, visual, infantile esotropia, motion, surgical procedures, operative, surgery specialty
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3432-3437. doi:https://doi.org/10.1167/iovs.08-1836

Glaucoma

Angiopoietin-like 7 Secretion Is Induced by Glaucoma Stimuli and Its Concentration Is Elevated in Glaucomatous Aqueous Humor Free
PDF
John Kuchtey; Maria E. Källberg; Kirk N. Gelatt; Tommy Rinkoski; András M. Komàromy; Rachel W. Kuchtey
Tags: angiopoietins, bodily secretions, glaucoma, hypertension, mass or substance concentration per volume
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3438-3448. doi:https://doi.org/10.1167/iovs.07-1347
Human Müller Stem Cell (MIO-M1) Transplantation in a Rat Model of Glaucoma: Survival, Differentiation, and Integration Free
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Natalie D. Bull; G. Astrid Limb; Keith R. Martin
Tags: glaucoma, stem cells, transplantation, eye
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3449-3456. doi:https://doi.org/10.1167/iovs.08-1770
Neural Rim Characteristics of Healthy South Indians: The Chennai Glaucoma Study Free
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Hemamalini Arvind; Ronnie George; Prema Raju; Ramesh S. Ve; Baskaran Mani; Prashanth Kannan; Lingam Vijaya
Tags: glaucoma, eye, cupping therapy, optic disk, nose
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3457-3464. doi:https://doi.org/10.1167/iovs.07-1210
Lack of Association between LOXL1 Variants and Primary Open-Angle Glaucoma in Three Different Populations Free
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Yutao Liu; Silke Schmidt; Xuejun Qin; Jason Gibson; Kristen Hutchins; Cecile Santiago-Turla; Janey L. Wiggs; Donald L. Budenz; Stephen Akafo; Pratap Challa; Leon W. Herndon; Michael A. Hauser; R. Rand Allingham
Tags: open-angle glaucoma
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3465-3468. doi:https://doi.org/10.1167/iovs.08-1850
Anterior Chamber Angle Measurement with Anterior Segment Optical Coherence Tomography: A Comparison between Slit Lamp OCT and Visante OCT Free
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Christopher Kai-shun Leung; Haitao Li; Robert Neal Weinreb; Jing Liu; Carol Yim Lui Cheung; Ricky Yiu Kwong Lai; Chi Pui Pang; Dennis Shun Chiu Lam
Tags: anterior chamber of eye, optical coherence tomography, slit lamps, transient ischemic attack, nose
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3469-3474. doi:https://doi.org/10.1167/iovs.07-1477

Immunology and Microbiology

Diminished Frequency and Function of CD4+CD25high Regulatory T Cells Associated with Active Uveitis in Vogt-Koyanagi-Harada Syndrome Free
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Lina Chen; Peizeng Yang; Hongyan Zhou; Hao He; Xiangrong Ren; Wei Chi; Li Wang; Aize Kijlstra
Tags: antigens, cd25, regulatory t-lymphocytes, uveomeningoencephalitic syndrome, uveitis, t-lymphocytes
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3475-3482. doi:https://doi.org/10.1167/iovs.08-1793

Lens

Visualization of In Situ Intracellular Aggregation of Two Cataract–Associated Human γ-Crystallin Mutants: Lose a Tail, Lose Transparency Free
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Venu Talla; Narayanaswamy Srinivasan; Dorairajan Balasubramanian
Tags: crystallins, cataract
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3483-3490. doi:https://doi.org/10.1167/iovs.07-1114

Physiology and Pharmacology

VIP and VIP Gene Silencing Modulation of Differentiation Marker N-Cadherin and Cell Shape of Corneal Endothelium in Human Corneas Ex Vivo Free
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Shay-Whey M. Koh; Krish Chandrasekara; Cara J. Abbondandolo; Timothy J. Coll; Allan R. Rutzen
Tags: cattle, cornea, donors, n-cadherins, corneal endothelium
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3491-3498. doi:https://doi.org/10.1167/iovs.07-1543

Retina

Aqueous Humor Levels of Vascular Endothelial Growth Factor in Retinitis Pigmentosa Free
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David Salom; Manuel Diaz-Llopis; Salvador García-Delpech; Patricia Udaondo; Maria Sancho-Tello; F. Javier Romero
Tags: aqueous humor, retinitis pigmentosa, vascular endothelial growth factor a
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3499-3502. doi:https://doi.org/10.1167/iovs.07-1168
Development and Characterization of an Adult Retinal Explant Organotypic Tissue Culture System as an In Vitro Intraocular Stem Cell Transplantation Model Free
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Thomas V. Johnson; Keith R. Martin
Tags: adult, body tissue, cell transplantation, eye, hematopoietic stem cell transplantation
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3503-3512. doi:https://doi.org/10.1167/iovs.07-1601
Engrafted Chicken Neural Tube–Derived Stem Cells Support the Innate Propensity for Axonal Regeneration within the Rat Optic Nerve Free
PDF
Petar Charalambous; Louise A. Hurst; Solon Thanos
Tags: axon, chickens, optic nerve, stem cells, transplantation
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3513-3524. doi:https://doi.org/10.1167/iovs.07-1473
Retinal Nerve Fiber Layer Analysis in RP Patients Using Fourier-Domain OCT Free
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Saloni Walia; Gerald A. Fishman
Tags: eye, retinal nerve fiber layer
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3525-3528. doi:https://doi.org/10.1167/iovs.08-1842
Differential Optical Densities of Intraretinal Spaces Free
PDF
Daniel Barthelmes; Florian K. P. Sutter; Mark C. Gillies
Tags: eye, interpersonal psychotherapy, optics, vitreous body, macular disorders
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3529-3534. doi:https://doi.org/10.1167/iovs.07-1320
Protective Effect of Thioredoxins 1 and 2 in Retinal Ganglion Cells after Optic Nerve Transection and Oxidative Stress Free
PDF
Yasunari Munemasa; Seok Hwan Kim; Jae Hong Ahn; Jacky M. K. Kwong; Joseph Caprioli; Natik Piri
Tags: optic nerve, oxidative stress, protein overexpression, retinal ganglion cells, thioredoxin
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3535-3543. doi:https://doi.org/10.1167/iovs.08-1716
Recording Focal Macular Photopic Negative Response (PhNR) from Monkeys Free
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Mineo Kondo; Yukihide Kurimoto; Takao Sakai; Toshiyuki Koyasu; Kentaro Miyata; Shinji Ueno; Hiroko Terasaki
Tags: cercopithecidae, luminance, electroretinography
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3544-3550. doi:https://doi.org/10.1167/iovs.08-1798
Correlation between Macular Volume and Focal Macular Electroretinogram in Patients with Retinitis Pigmentosa Free
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Tadasu Sugita; Mineo Kondo; Chang-Hua Piao; Yasuki Ito; Hiroko Terasaki
Tags: electroretinography, retinitis pigmentosa, volume
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3551-3558. doi:https://doi.org/10.1167/iovs.08-1954
Müller Cell Response to Blue Light Injury of the Rat Retina Free
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Ianors Iandiev; Antje Wurm; Margrit Hollborn; Peter Wiedemann; Christian Grimm; Charlotte E. Remé; Andreas Reichenbach; Thomas Pannicke; Andreas Bringmann
Tags: blue light, edema, retina, wounds and injuries, retinal degeneration
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3559-3567. doi:https://doi.org/10.1167/iovs.08-1723
A Novel Method for Objective Vision Testing in Canine Models of Inherited Retinal Disease Free
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Patricia M. Gearhart; Chris C. Gearhart; Simon M. Petersen-Jones
Tags: dog, domestic, vision tests, retinal diseases
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3568-3576. doi:https://doi.org/10.1167/iovs.07-0625
Computerized Analysis of Retinal Vessel Width and Tortuosity in Premature Infants Free
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Clare M. Wilson; Kenneth D. Cocker; Merrick J. Moseley; Carl Paterson; Simon T. Clay; William E. Schulenburg; Monte D. Mills; Anna L. Ells; Kim H. Parker; Graham E. Quinn; Alistair R. Fielder; Jeffrey Ng
Tags: infant, premature, retinal vessels, software, pixel, infant
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3577-3585. doi:https://doi.org/10.1167/iovs.07-1353
Dietary Omega-3 Fatty Acids and Ganglion Cell Function Free
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Christine T. O. Nguyen; Algis J. Vingrys; Bang V. Bui
Tags: diet, electroretinography, fatty acids, ganglia, omega-3 fatty acids
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3586-3594. doi:https://doi.org/10.1167/iovs.08-1735
Early Inner Retinal Dysfunction in Streptozotocin-Induced Diabetic Rats Free
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Kenichi Kohzaki; Algis J. Vingrys; Bang V. Bui
Tags: diabetes mellitus, rats, streptozocin, pathophysiology
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3595-3604. doi:https://doi.org/10.1167/iovs.08-1679
Deleterious Role of TNF-α in Retinal Ischemia–Reperfusion Injury Free
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Samuel Berger; Sean I. Savitz; Sheetal Nijhawan; Manjeet Singh; Joel David; Pearl S. Rosenbaum; Daniel M. Rosenbaum
Tags: reperfusion injury, retinal ischemia, tumor necrosis factors, ischemia
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3605-3610. doi:https://doi.org/10.1167/iovs.07-0817
VEGF Polymorphisms Are Associated with Severity of Diabetic Retinopathy Free
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Amanda J. Churchill; James G. Carter; Conor Ramsden; Steven J. Turner; Anna Yeung; Paul E. C. Brenchley; David W. Ray
Tags: diabetic retinopathy, genotype, haplotypes, polymorphism, single nucleotide polymorphism
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3611-3616. doi:https://doi.org/10.1167/iovs.07-1383
A New Method to Monitor Visual Field Defects Caused by Photoreceptor Degeneration by Quantitative Optical Coherence Tomography Free
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M. Dominik Fischer; Johannes C. Fleischhauer; Mark C. Gillies; Florian K. Sutter; Horst Helbig; Daniel Barthelmes
Tags: optical coherence tomography, photoreceptors, scotoma, tissue degeneration, visual fields
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3617-3621. doi:https://doi.org/10.1167/iovs.08-2003

Retinal Cell Biology

The Proteasome: A Target of Oxidative Damage in Cultured Human Retina Pigment Epithelial Cells Free
PDF
Xinyu Zhang; Jilin Zhou; Alexandre F. Fernandes; Janet R. Sparrow; Paulo Pereira; Allen Taylor; Fu Shang
Tags: multicatalytic endopeptidase complex, oxidative stress, pigment, ubiquitin, proteins
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3622-3630. doi:https://doi.org/10.1167/iovs.07-1559
Topical Doxycycline Can Induce Expression of BDNF in Transduced Retinal Pigment Epithelial Cells Transplanted into the Subretinal Space Free
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Toshiaki Abe; Ryosuke Wakusawa; Haruka Seto; Nobuharu Asai; Takae Saito; Kohji Nishida
Tags: brain-derived neurotrophic factor, retinal pigment cell, transplantation, eyedrops, doxycycline
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3631-3639. doi:https://doi.org/10.1167/iovs.07-0947
Vascular Endothelial Growth Factor Induces MEF2C and MEF2-Dependent Activity in Endothelial Cells Free
PDF
Debasish Maiti; Zhenhua Xu; Elia J. Duh
Tags: endothelial cells, mef2 transcription factors, vascular endothelial growth factor a
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3640-3648. doi:https://doi.org/10.1167/iovs.08-1760
In Vivo Visualization of Dendritic Cells, Macrophages, and Microglial Cells Responding to Laser-Induced Damage in the Fundus of the Eye Free
PDF
Nicole Eter; Daniel R. Engel; Linda Meyer; Hans-Martin Helb; Felix Roth; Juliane Maurer; Frank G. Holz; Christian Kurts
Tags: choroid, eye, lasers, retina, flow cytometry
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3649-3658. doi:https://doi.org/10.1167/iovs.07-1322
Abnormal Reactivity of Müller Cells after Retinal Detachment in Mice Deficient in GFAP and Vimentin Free
PDF
Mark R. Verardo; Geoffrey P. Lewis; Masumi Takeda; Kenneth A. Linberg; Jiyun Byun; Gabriel Luna; Ulrika Wilhelmsson; Milos Pekny; Dong-Feng Chen; Steven K. Fisher
Tags: glial fibrillary acidic protein, mice, retina, retinal detachment, vimentin
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3659-3665. doi:https://doi.org/10.1167/iovs.07-1474
Dendritic Cells Augment Choroidal Neovascularization Free
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Kei Nakai; Ofer Fainaru; Lauren Bazinet; Pouya Pakneshan; Ofra Benny; Elke Pravda; Judah Folkman; Robert J. D'Amato
Tags: choroidal neovascularization, dendritic cells
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3666-3670. doi:https://doi.org/10.1167/iovs.07-1640
Rodent Anterior Ischemic Optic Neuropathy (rAION) Induces Regional Retinal Ganglion Cell Apoptosis with a Unique Temporal Pattern Free
PDF
Bernard J. Slater; Zara Mehrabian; Yan Guo; Allan Hunter; Steven L. Bernstein
Tags: annexin a5, anterior ischemic optic neuropathy, apoptosis, retinal ganglion cells, rodentia
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3671-3676. doi:https://doi.org/10.1167/iovs.07-0504
Synaptic Pathology in Retinoschisis Knockout (Rs1 −/y ) Mouse Retina and Modification by rAAV-Rs1 Gene Delivery Free
PDF
Yuichiro Takada; Camasamudram Vijayasarathy; Yong Zeng; Sten Kjellstrom; Ronald A. Bush; Paul A. Sieving
Tags: genes, mice, retina, retinoschisis, proteins
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3677-3686. doi:https://doi.org/10.1167/iovs.07-1071
PDGF- and Insulin/IGF-1–Specific Distinct Modes of Class IA PI 3-Kinase Activation in Normal Rat Retinas and RGC-5 Retinal Ganglion Cells Free
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Swarajit K. Biswas; Yan Zhao; Arumugam Nagalingam; Thomas W. Gardner; Lakshman Sandirasegarane
Tags: 1-phosphatidylinositol 3-kinase, insulin, insulin-like growth factor i, platelet-derived growth factor, retina
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3687-3698. doi:https://doi.org/10.1167/iovs.07-1455
Characterization of a Spontaneous Mouse Retinal Pigment Epithelial Cell Line B6-RPE07 Free
PDF
Mei Chen; Elizabeth Muckersie; Marie Robertson; Monika Fraczek; John V. Forrester; Heping Xu
Tags: mice, retinal pigment cell, chemokines, cytokine, proteins
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3699-3706. doi:https://doi.org/10.1167/iovs.07-1522

Visual Neuroscience

Autoimmune Optic Neuritis in the Common Marmoset Monkey: Comparison of Visual Evoked Potentials with MRI and Histopathology Free
PDF
Ricarda Diem; Iris Demmer; Susann Boretius; Doron Merkler; Barthel Schmelting; Sarah K. Williams; Muriel B. Sättler; Mathias Bähr; Thomas Michaelis; Jens Frahm; Wolfgang Brück; Eberhard Fuchs
Tags: autoimmune diseases, callithrix, cercopithecidae, evoked potentials, visual, histopathology tests
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3707-3714. doi:https://doi.org/10.1167/iovs.08-1896

Visual Psychophysics and Physiological Optics

Light-Induced Retinal Changes Observed with High-Resolution Autofluorescence Imaging of the Retinal Pigment Epithelium Free
PDF
Jessica I. W. Morgan; Jennifer J. Hunter; Benjamin Masella; Robert Wolfe; Daniel C. Gray; William H. Merigan; François C. Delori; David R. Williams
Tags: autofluorescence, diagnostic imaging, lasers, retina, retinal pigment cell
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3715-3729. doi:https://doi.org/10.1167/iovs.07-1430
Resolution Visual Fields in Children Surgically Treated for Bilateral Congenital Cataract Free
PDF
Lene Martin; Gunilla Magnusson; Zoran Popovic; Johan Sjöstrand
Tags: cataract, child, congenital cataract, surgical procedures, operative, visual fields
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3730-3733. doi:https://doi.org/10.1167/iovs.07-1558
The Effect of Age and Fixation Instability on Retinotopic Mapping of Primary Visual Cortex Free
PDF
Michael D. Crossland; Antony B. Morland; Mary P. Feely; Elisabeth von dem Hagen; Gary S. Rubin
Tags: functional magnetic resonance imaging, primary visual cortex
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3734-3739. doi:https://doi.org/10.1167/iovs.07-1621

Clinical Trials

Corneal Hysteresis but Not Corneal Thickness Correlates with Optic Nerve Surface Compliance in Glaucoma Patients Free
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Anthony P. Wells; David F. Garway-Heath; Ali Poostchi; Tracey Wong; Kenneth C. Y. Chan; Nisha Sachdev
Tags: cornea, corneal hysteresis, glaucoma, optic nerve, intraocular pressure
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3262-3268. doi:https://doi.org/10.1167/iovs.07-1556
Brightness, Contrast, and Color Balance of Digital versus Film Retinal Images in the Age-Related Eye Disease Study 2 Free
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Larry D. Hubbard; Ronald P. Danis; Michael W. Neider; Dennis W. Thayer; Hugh D. Wabers; James K. White; Anthony J. Pugliese; Michael F. Pugliese
Tags: balance, device, color, eye diseases, equilibrium
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3269-3282. doi:https://doi.org/10.1167/iovs.07-1267

Perspective

An Hypothesis to Account for the Renewal of Outer Segments in Rod and Cone Photoreceptor Cells: Renewal as a Surrogate Antioxidant Free
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Barry S. Winkler
Tags: antioxidants, retinal cone, rod photoreceptors
Investigative Ophthalmology & Visual Science August 2008, Vol.49, 3259-3261. doi:https://doi.org/10.1167/iovs.08-1785
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