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Anatomy and Pathology/Oncology

Selective Breeding for Susceptibility to Myopia Reveals a Gene–Environment Interaction Free
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Yen-Po Chen; Paul M. Hocking; Ling Wang; Boris Považay; Ankush Prashar; Chi-Ho To; Jonathan T. Erichsen; Marita Feldkaemper; Bernd Hofer; Wolfgang Drexler; Frank Schaeffel; Jeremy A. Guggenheim
Tags: breeding, disease susceptibility, myopia, vision
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4003-4011. doi:10.1167/iovs.10-7044
Heritability of Ocular Component Dimensions in Chickens: Genetic Variants Controlling Susceptibility to Experimentally Induced Myopia and Pretreatment Eye Size Are Distinct Free
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Yen-Po Chen; Ankush Prashar; Jonathan T. Erichsen; Chi-Ho To; Paul M. Hocking; Jeremy A. Guggenheim
Tags: chickens, disease susceptibility, eye, genetics, myopia
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4012-4020. doi:10.1167/iovs.10-7045
Comparative Toxicology of Trypan Blue, Brilliant Blue G, and Their Combination Together with Polyethylene Glycol on Human Pigment Epithelial Cells Free
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Doaa Awad; Imke Schrader; Melinda Bartok; Andreas Mohr; Detlef Gabel
Tags: brilliant blue g, dyes, polyethylene glycols, toxic effect, trypan blue
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4085-4090. doi:10.1167/iovs.10-6336
Disturbed Matrix Metalloproteinase Activity of Bruch's Membrane in Age-Related Macular Degeneration Free
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Ali A. Hussain; Yunhee Lee; Jin-Jun Zhang; John Marshall
Tags: age-related macular degeneration, bruch's basal membrane, donors, gelatinase a, gelatinase b
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4459-4466. doi:10.1167/iovs.10-6678

Biochemistry and Molecular Biology

Postnatal Changes in the Developing Rat Extraocular Muscles Free
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Carole L. Moncman; Miguel E. Andrade; Francisco H. Andrade
Tags: adult, antibodies, muscle, muscle of orbit, myosin
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 3962-3969. doi:10.1167/iovs.10-6866
Autophagy Activation in the Injured Photoreceptor Inhibits Fas-Mediated Apoptosis Free
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Cagri G. Besirli; Nicholas D. Chinskey; Qiong-Duan Zheng; David N. Zacks
Tags: apoptosis, autophagy, photoreceptors, retina, retinal detachment
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4193-4199. doi:10.1167/iovs.10-7090
Mitochondrial Localization and Ocular Expression of Mutant Opa3 in a Mouse Model of 3-Methylglutaconicaciduria Type III Free
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Kate A. Powell; Jennifer R. Davies; Elaine Taylor; Michael A. Wride; Marcela Votruba
Tags: lens (device), mice, mitochondria, proteins, antibodies
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4369-4380. doi:10.1167/iovs.10-6406
Molecular Consequences of BEST1 Gene Mutations in Canine Multifocal Retinopathy Predict Functional Implications for Human Bestrophinopathies Free
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Karina E. Guziewicz; Julianna Slavik; Sarah J. P. Lindauer; Gustavo D. Aguirre; Barbara Zangerl
Tags: dog, domestic, mutation, proteins, retinal diseases, rna, messenger
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4497-4505. doi:10.1167/iovs.10-6385
Surface Chemistry Study of the Interactions of Benzalkonium Chloride with Films of Meibum, Corneal Cells Lipids, and Whole Tears Free
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Georgi A. Georgiev; Norihiko Yokoi; Krassimir Koev; Elena Kutsarova; Slavyana Ivanova; Alexander Kyumurkov; Albena Jordanova; Rumen Krastev; Zdravko Lalchev
Tags: bacterial artificial chromosomes, blood alcohol concentration, bronchioloalveolar carcinoma, lipids, cornea
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4645-4654. doi:10.1167/iovs.10-6271
Expression and Regulation of Antimicrobial Peptide Psoriasin (S100A7) at the Ocular Surface and in the Lacrimal Apparatus Free
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Fabian Garreis; Maria Gottschalt; Thomas Schlorf; Regine Gläser; Jürgen Harder; Dieter Worlitzsch; Friedrich P. Paulsen
Tags: antimicrobials, body tissue, lacrimal apparatus, peptides, regulation
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4914-4922. doi:10.1167/iovs.10-6598

Clinical and Epidemiologic Research

Refractive and Corneal Astigmatism in White School Children in Northern Ireland Free
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Lisa O'Donoghue; Alicja R. Rudnicka; Julie F. McClelland; Nicola S. Logan; Christopher G. Owen; Kathryn J. Saunders
Tags: astigmatism, cornea, school-age child
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4048-4053. doi:10.1167/iovs.10-6100
Quality of Life and Near Vision Impairment Due to Functional Presbyopia among Rural Chinese Adults Free
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Qing Lu; Nathan Congdon; Xiangdong He; Gudlavalleti V. S. Murthy; Amy Yang; Wei He
Tags: adult, impairment, myopia, presbyopia, quality of life
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4118-4123. doi:10.1167/iovs.10-6353
Prevalence of Corneal Astigmatism in Tohono O'odham Native American Children 6 Months to 8 Years of Age Free
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Erin M. Harvey; Velma Dobson; Joseph M. Miller; Jim Schwiegerling; Candice E. Clifford-Donaldson; Tina K. Green; Dawn H. Messer
Tags: astigmatism, child, cornea, prevalence, native americans
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4350-4355. doi:10.1167/iovs.10-6061
Incidence of Blindness and Severe Visual Impairment in Germany: Projections for 2030 Free
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Robert P. Finger; Rolf Fimmers; Frank G. Holz; Hendrik P. N. Scholl
Tags: blindness, germany, incidence, visual impairment
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4381-4389. doi:10.1167/iovs.10-6987
Are Obesity and Anthropometry Risk Factors for Diabetic Retinopathy?: The Diabetes Management Project Free
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Mohamed Dirani; Jing Xie; Eva Fenwick; Rehab Benarous; Gwyneth Rees; Tien Yin Wong; Ecosse L. Lamoureux
Tags: anthropometry, body mass index procedure, diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4416-4421. doi:10.1167/iovs.11-7208
Association of Mean Ocular Perfusion Pressure and Diabetic Retinopathy in Type 2 Diabetes Mellitus: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DR... Free
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Rajiv Raman; Aditi Gupta; Vaitheeswaran Kulothungan; Tarun Sharma
Tags: diabetes mellitus, type 2, diabetic retinopathy, dreams, epidemiology, genetics, molecular
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4592-4597. doi:10.1167/iovs.10-6903
Circulating Angiopoietic Cells and Diabetic Retinopathy in Type 2 Diabetes Mellitus, with or without Macrovascular Disease Free
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Simon Brunner; Florian Hoellerl; Katharina E. Schmid-Kubista; Florian Zeiler; Guntram Schernthaner; Susanne Binder; Gerit-Holger Schernthaner
Tags: diabetes mellitus, type 2, diabetic retinopathy, retinal diseases, stem cells
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4655-4662. doi:10.1167/iovs.10-6520
A Comparison of Standard Scoring versus Rasch Scoring of the Visual Function Index-14 in Patients with Cataracts Free
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Carlota Las Hayas; Amaia Bilbao; Jose M. Quintana; Susana Garcia; Iratxe Lafuente; the IRYSS Cataract Group
Tags: cataract, rasch model, vision, preoperative care, surgical procedures, operative
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4800-4807. doi:10.1167/iovs.10-6132
Corneal Biomechanics, Refractive Error, and Axial Length in Chinese Primary School Children Free
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Yuqiang Huang; Chukai Huang; Liping Li; Kunliang Qiu; Weifen Gong; Zhenmao Wang; Xuefen Wu; Yali Du; Bin Chen; Dennis S. C. Lam; Mingzhi Zhang; Nathan Congdon
Tags: chinese (other dialects), chinese people, cornea, refractive errors, school-age child
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4923-4928. doi:10.1167/iovs.10-6211

Cornea

Vector Analysis of Evolutive Corneal Astigmatic Changes in Keratoconus Free
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David P. Piñero; Jorge L. Alio; Javier Tomás; Miguel J. Maldonado; Miguel A. Teus; Rafael I. Barraquer
Tags: cornea, follow-up, keratoconus, spatial vectors, astigmatism
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4054-4062. doi:10.1167/iovs.10-6856
Characterization of Soft Contact Lens Edge Fitting Using Ultra-High Resolution and Ultra-Long Scan Depth Optical Coherence Tomography Free
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Meixiao Shen; Lele Cui; Colleen Riley; Michael R. Wang; Jianhua Wang
Tags: contact lenses, contact lenses, hydrophilic, lens (device), lens, crystalline, optical coherence tomography
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4091-4097. doi:10.1167/iovs.10-6507
Overexpression of Pax6 in Mouse Cornea Directly Alters Corneal Epithelial Cells: Changes in Immune Function, Vascularization, and Differentiation Free
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Janine Davis; Joram Piatigorsky
Tags: cornea, mice, protein overexpression, genes, corneal epithelial cells
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4158-4168. doi:10.1167/iovs.10-6726
Quantitative Assessment of UVA-Riboflavin Corneal Cross-Linking Using Nonlinear Optical Microscopy Free
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Dongyul Chai; Ronald N. Gaster; Roberto Roizenblatt; Tibor Juhasz; Donald J. Brown; James V. Jester
Tags: autofluorescence, collagen, cornea, corneal collagen cross-linking, optics
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4231-4238. doi:10.1167/iovs.10-7105
Degradation Studies and Biological Behavior on an Artificial Cornea Material Free
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Lívia Santos; Maria Pia Ferraz; Yuki Shirosaki; Maria Ascensão Lopes; Maria Helena Fernandes; Akiyoshi Osaka; José Domingos Santos
Tags: catabolism, cornea, porosity, cell culture techniques
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4274-4281. doi:10.1167/iovs.10-6861
Herpes Simplex Virus Type 1–Induced Transcriptional Networks of Corneal Endothelial Cells Indicate Antigen Presentation Function Free
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Dai Miyazaki; Tomoko Haruki; Sachiko Takeda; Shin-ichi Sasaki; Keiko Yakura; Yuki Terasaka; Naoki Komatsu; Satoru Yamagami; Hirokazu Touge; Chizu Touge; Yoshitsugu Inoue
Tags: antigen processing and presentation, cornea, endothelial cells, human herpesvirus 1, transcription, genetic
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4282-4293. doi:10.1167/iovs.10-6911
Age-Related Differences in the Elasticity of the Human Cornea Free
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Nathaniel E. Knox Cartwright; John R Tyrer; John Marshall
Tags: cornea, elasticity
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4324-4329. doi:10.1167/iovs.09-4798
ABCG2-Dependent Dye Exclusion Activity and Clonal Potential in Epithelial Cells Continuously Growing for 1 Month from Limbal Explants Free
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Ozlëm Barut Selver; Alexander Barash; Mohaned Ahmed; J. Mario Wolosin
Tags: body tissue, dyes, epithelial cells, oryctolagus cuniculus, toxic effect
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4330-4337. doi:10.1167/iovs.10-5897
Estimating a Just-Noticeable Difference for Ocular Comfort in Contact Lens Wearers Free
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Eric B. Papas; Lisa Keay; Blanka Golebiowski
Tags: contact lenses, eye, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4390-4394. doi:10.1167/iovs.10-7051
Epidermal Differentiation and Loss of Clonal Growth Potential of Human Limbal Basal Epithelial Progenitor Cells during Intrastromal Invasion Free
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Ek Kia Tan; Hua He; Scheffer C. G. Tseng
Tags: epithelium, stem cells, epidermis
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4534-4545. doi:10.1167/iovs.10-6376
STAT3 Regulates the Proliferation and Differentiation of Rabbit Limbal Epithelial Cells via a ΔNp63-Dependent Mechanism Free
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Yi-Jen Hsueh; Hung-Chi Chen; Wing-Keung Chu; Chien-Chia Cheng; Pei-Ching Kuo; Liang-Yu Lin; Hui-Kang Ma; Jan-Kan Chen
Tags: stat3 protein, oryctolagus cuniculus, epithelial cells
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4685-4693. doi:10.1167/iovs.10-6103
Wnt/β-Catenin Signaling Regulates Proliferation of Human Cornea Epithelial Stem/Progenitor Cells Free
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Martin N. Nakatsu; Zhenhua Ding; Madelena Y. Ng; Thuy T. Truong; Fei Yu; Sophie X. Deng
Tags: cornea, epithelium, signal transduction, stem cells, epithelial cells
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4734-4741. doi:10.1167/iovs.10-6486
Very Late Antigen-1 Mediates Corneal Lymphangiogenesis Free
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Sammy Grimaldo; Don Yuen; Tatiana Ecoiffier; Lu Chen
Tags: antigens, cornea, integrin alpha-1 beta-1, lymphangiogenesis, lymphatic vessel
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4808-4812. doi:10.1167/iovs.10-6580
Significant Inhibition of Corneal Scarring In Vivo with Tissue-Selective, Targeted AAV5 Decorin Gene Therapy Free
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Rajiv R. Mohan; Ashish Tandon; Ajay Sharma; John W. Cowden; Jonathan C. K. Tovey
Tags: body tissue, cornea, fibrosis, gene therapy, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4833-4841. doi:10.1167/iovs.11-7357

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology

Sustained Release of Bone Morphogenetic Protein-4 in Adult Rabbit Extraocular Muscle Results in Decreased Force and Muscle Size: Potential for Strabismus Treatment Free
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Brian C. Anderson; Mark L. Daniel; Jeffrey D. Kendall; Stephen P. Christiansen; Linda K. McLoon
Tags: adult, muscle, muscle of orbit, oryctolagus cuniculus, proteins
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4021-4029. doi:10.1167/iovs.10-6878
Fourier-Domain OCT in Multiple Sclerosis Patients: Reproducibility and Ability to Detect Retinal Nerve Fiber Layer Atrophy Free
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Elena Garcia-Martin; Victoria Pueyo; Isabel Pinilla; Jose-Ramon Ara; Jesus Martin; Javier Fernandez
Tags: atrophy, eye, multiple sclerosis, retinal nerve fiber layer
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4124-4131. doi:10.1167/iovs.10-6643
The Role of Suppression in Amblyopia Free
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Jingrong Li; Benjamin Thompson; Carly S. Y. Lam; Daming Deng; Lily Y. L. Chan; Goro Maehara; George C. Woo; Minbin Yu; Robert F. Hess
Tags: amblyopia, balance, device, equilibrium, eye
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4169-4176. doi:10.1167/iovs.11-7233
Subjective Fixation Disparity Affected by Dynamic Asymmetry, Resting Vergence, and Nonius Bias Free
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Aiga Švede; Jörg Hoormann; Stephanie Jainta; Wolfgang Jaschinski
Tags: vision disparity, strabismus
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4356-4361. doi:10.1167/iovs.10-6499
Optic Nerve Projections in Patients with Primary Ciliary Dyskinesia Free
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Michael B. Hoffmann; Barbara Wolynski; Michael Bach; Synke Meltendorf; Wolfgang Behrens-Baumann; Franziska Golla
Tags: evoked potentials, visual, kartagener's syndrome, optic nerve, albinism, visual fields
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4617-4625. doi:10.1167/iovs.11-7194
Adaptation of Reactive Saccades in Normal Children Free
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Karine Doré-Mazars; Dorine Vergilino-Perez; Christelle Lemoine; Maria Pia Bucci
Tags: child, saccades, well child, adult, extinction, psychological
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4813-4818. doi:10.1167/iovs.10-6626
Different Impact of ALS on Laminin Isoforms in Human Extraocular Muscles versus Limb Muscles Free
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Jing-Xia Liu; Thomas Brännström; Peter M. Andersen; Fatima Pedrosa-Domellöf
Tags: antibodies, donors, laminin, limb, muscle
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4842-4852. doi:10.1167/iovs.10-7132
Brief Daily Periods of Unrestricted Vision Preserve Stereopsis in Strabismus Free
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Janice M. Wensveen; Earl L. Smith, III; Li-Fang Hung; Ronald S. Harwerth
Tags: cercopithecidae, contrast sensitivity, depth perception, prisms, strabismus
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4872-4879. doi:10.1167/iovs.10-6891

Genetics

Four-Year Follow-up of Diagnostic Service in USH1 Patients Free
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Anne-Françoise Roux; Valérie Faugère; Christel Vaché; David Baux; Thomas Besnard; Susana Léonard; Catherine Blanchet; Christian Hamel; Michel Mondain; Brigitte Gilbert-Dussardier; Patrick Edery; Didier Lacombe; Dominique Bonneau; Muriel Holder-Espinasse; Umberto Ambrosetti; Hubert Journel; Albert David; Geneviève Lina-Granade; Sue Malcolm; Mireille Claustres
Tags: diagnostic services, follow-up, genes, genotype, mutation
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4063-4071. doi:10.1167/iovs.10-6869
Genetic Dissection of the Gpnmb Network in the Eye Free
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Hong Lu; Xusheng Wang; Matthew Pullen; Huaijin Guan; Hui Chen; Shwetapadma Sahu; Bing Zhang; Hao Chen; Robert W. Williams; Eldon E. Geisert; Lu Lu; Monica M. Jablonski
Tags: eye, genes, genetics, mice, tissue dissection
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4132-4142. doi:10.1167/iovs.10-6493
Genetic Heterogeneity for Recessively Inherited Congenital Cataract Microcornea with Corneal Opacity Free
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Kamron Khan; Ahmed Al-Maskari; Martin McKibbin; Ian M. Carr; Adam Booth; Moin Mohamed; Salina Siddiqui; James A. Poulter; David A. Parry; Clara V. Logan; Anwar Hashmi; Tehseen Sahi; Hussain Jafri; Yasmin Raashid; Colin A. Johnson; Alex F. Markham; Carmel Toomes; Aine Rice; Eamonn Sheridan; Chris F. Inglehearn; Manir Ali
Tags: congenital cataract, corneal opacity, genetic heterogeneity, microcornea, family
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4294-4299. doi:10.1167/iovs.10-6776
Association of Variants in the LIPC and ABCA1 Genes with Intermediate and Large Drusen and Advanced Age-Related Macular Degeneration Free
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Yi Yu; Robyn Reynolds; Jesen Fagerness; Bernard Rosner; Mark J. Daly; Johanna M. Seddon
Tags: abca1 gene, age-related macular degeneration, drusen, genes
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4663-4670. doi:10.1167/iovs.10-7070
Genetic Association with Response to Intravitreal Ranibizumab in Patients with Neovascular AMD Free
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Barbara Kloeckener-Gruissem; Daniel Barthelmes; Stephan Labs; Christian Schindler; Malaika Kurz-Levin; Stephan Michels; Johannes Fleischhauer; Wolfgang Berger; Florian Sutter; Moreno Menghini
Tags: exudative age-related macular degeneration, genetics, ranibizumab, single nucleotide polymorphism, genotype
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4694-4702. doi:10.1167/iovs.10-6080
An ENU-Induced Mutation in the Mertk Gene (Mertknmf12 ) Leads to a Slow Form of Retinal Degeneration Free
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Dennis M. Maddox; Wanda L. Hicks; Douglas Vollrath; Matthew M. LaVail; Jürgen K. Naggert; Patsy M. Nishina
Tags: mertk gene, mutation, retinal degeneration, mice, tumor necrosis factors
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4703-4709. doi:10.1167/iovs.10-7077
Mitochondrial Haplogroup Background May Influence Southeast Asian G11778A Leber Hereditary Optic Neuropathy Free
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Supannee Kaewsutthi; Nopasak Phasukkijwatana; Yutthana Joyjinda; Wanicha Chuenkongkaew; Bussaraporn Kunhapan; Aung Win Tun; Bhoom Suktitipat; Patcharee Lertrit
Tags: asian, dna, mitochondrial, optic atrophy, hereditary, leber, mitochondria
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4742-4748. doi:10.1167/iovs.10-5816
Autosomal Recessive Stickler Syndrome in Two Families Is Caused by Mutations in the COL9A1 Gene Free
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Konstantinos Nikopoulos; Isabelle Schrauwen; Marleen Simon; Rob W. J. Collin; Marc Veckeneer; Kathelijn Keymolen; Guy Van Camp; Frans P. M. Cremers; L. Ingeborgh van den Born
Tags: autosomal recessive inheritance, family, genes, mutation, stickler syndrome
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4774-4779. doi:10.1167/iovs.10-7128
Association of 15q14 and 15q25 with High Myopia in Japanese Free
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Hisako Hayashi; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Yumiko Kurashige; Akitaka Tsujikawa; Muka Moriyama; Kyoko Ohno-Matsui; Manabu Mochizuki; Mineo Ozaki; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
Tags: japanese, myopia, single nucleotide polymorphism
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4853-4858. doi:10.1167/iovs.11-7311

Glaucoma

Ex Vivo Optical Coherence Tomography Imaging of Collector Channels with a Scanning Endoscopic Probe Free
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Jian Ren; Henrick K. Gille; Jigang Wu; Changhuei Yang
Tags: diagnostic imaging, endoscopy, optical coherence tomography, body tissue, needle device
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 3921-3925. doi:10.1167/iovs.10-6744
Appositional Closure Identified by Ultrasound Biomicroscopy in Population-Based Primary Angle-Closure Glaucoma Suspects: The Liwan Eye Study Free
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Xiangbin Kong; Paul J. Foster; Qunxiao Huang; Yingfeng Zheng; Wenyong Huang; Xiaoyu Cai; Mingguang He
Tags: angle closure glaucoma, eye, ultrasound biomicroscopy, gonioscopy, isolated tumor cells
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 3970-3975. doi:10.1167/iovs.10-6412
Gaze Behavior among Experts and Trainees during Optic Disc Examination: Does How We Look Affect What We See? Free
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Evelyn C. O'Neill; Yu Xiang George Kong; Paul P. Connell; Dai Ni Ong; Sharon A. Haymes; Michael A. Coote; Jonathan G. Crowston
Tags: gaze, glaucoma, optic disk, retinal nerve fiber layer, ophthalmology
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 3976-3983. doi:10.1167/iovs.10-6912
Properties of the Statpac Visual Field Index Free
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Paul H. Artes; Neil O'Leary; Donna M. Hutchison; Lisa Heckler; Glen P. Sharpe; Marcelo T. Nicolela; Balwantray C. Chauhan
Tags: visual fields
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4030-4038. doi:10.1167/iovs.10-6905
Two-Photon Imaging of the Mouse Eye Free
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Andrew W. Johnson; David A. Ammar; Malik Y. Kahook
Tags: diagnostic imaging, eye, mice, photons, glaucoma
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4098-4105. doi:10.1167/iovs.10-7115
Retinal Ganglion Cell Loss in Superoxide Dismutase 1 Deficiency Free
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Kenya Yuki; Yoko Ozawa; Tetsu Yoshida; Toshihide Kurihara; Manabu Hirasawa; Naoki Ozeki; Daisuke Shiba; Kousuke Noda; Susumu Ishida; Kazuo Tsubota
Tags: intraocular pressure, mice, retinal ganglion cells, sod1 gene, superoxide dismutase 1
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4143-4150. doi:10.1167/iovs.10-6294
The Association between Primary Open-Angle Glaucoma and Motor Vehicle Collisions Free
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Sachiko Tanabe; Kenya Yuki; Naoki Ozeki; Daisuke Shiba; Takayuki Abe; Keisuke Kouyama; Kazuo Tsubota
Tags: accidents, traffic, open-angle glaucoma, glaucoma, medical history
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4177-4181. doi:10.1167/iovs.10-6264
The Bugeye Mutant Zebrafish Exhibits Visual Deficits that Arise with the Onset of an Enlarged Eye Phenotype Free
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Joseph M. Stujenske; John E. Dowling; Farida Emran
Tags: eye, phenotype, retina, zebrafish, electroretinography
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4200-4207. doi:10.1167/iovs.10-6434
Pattern Electroretinogram in Glaucoma Suspects: New Findings from a Longitudinal Study Free
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Sebastian F. N. Bode; Thomas Jehle; Michael Bach
Tags: electroretinography, glaucoma, longitudinal studies
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4300-4306. doi:10.1167/iovs.10-6381
β-Zone Parapapillary Atrophy and the Rate of Retinal Nerve Fiber Layer Thinning in Glaucoma Free
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Eun Ji Lee; Tae-Woo Kim; Robert N. Weinreb; Ki Ho Park; Seok Hwan Kim; Dong Myung Kim
Tags: atrophy, glaucoma, retinal nerve fiber layer, eye
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4422-4427. doi:10.1167/iovs.10-6818
Systemic Vascular Dysregulation and Retrobulbar Hemodynamics in Normal-Tension Glaucoma Free
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Fernando Galassi; Barbara Giambene; Roberta Varriale
Tags: endothelin-1, glaucoma, normal-tension, hemodynamics
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4467-4471. doi:10.1167/iovs.10-6710
Transplantation of BDNF-Secreting Mesenchymal Stem Cells Provides Neuroprotection in Chronically Hypertensive Rat Eyes Free
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Matthew M. Harper; Sinisa D. Grozdanic; Bas Blits; Markus H. Kuehn; Daniel Zamzow; Janice E. Buss; Randy H. Kardon; Donald S. Sakaguchi
Tags: brain-derived neurotrophic factor, eye, hypertension, transplantation, stem cell, mesenchymal
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4506-4515. doi:10.1167/iovs.11-7346
The Impact of Retardance Pattern Variability on Nerve Fiber Layer Measurements over Time Using GDx with Variable and Enhanced Corneal Compensation Free
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Dilraj S. Grewal; Mitra Sehi; Richard J. Cook; David S. Greenfield; Advanced Imaging in Glaucoma Study Group
Tags: cornea, eye, follow-up, glaucoma, manf gene
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4516-4524. doi:10.1167/iovs.10-5969
Blink Frequency and Duration during Perimetry and Their Relationship to Test–Retest Threshold Variability Free
PDF
Yanfang Wang; Sonia S. Toor; Ramesh Gautam; David B. Henson
Tags: perimetry, visual field testing, blinking
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4546-4550. doi:10.1167/iovs.10-6553
Association between SRBD1 and ELOVL5 Gene Polymorphisms and Primary Open-Angle Glaucoma Free
PDF
Fumihiko Mabuchi; Yoichi Sakurada; Kenji Kashiwagi; Zentaro Yamagata; Hiroyuki Iijima; Shigeo Tsukahara
Tags: genes, open-angle glaucoma, polymorphism, glaucoma
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4626-4629. doi:10.1167/iovs.11-7382

Immunology and Microbiology

Interferon-gamma, Macrophages, and Virus Spread after HSV-1 Injection Free
PDF
Heather M. Cathcart; Mei Zheng; Jason J. Covar; Yi Liu; Robert Podolsky; Sally S. Atherton
Tags: eye, human herpesvirus 1, macrophage, mice, viruses
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 3984-3993. doi:10.1167/iovs.10-6449
NOD2 Deficiency Results in Increased Susceptibility to Peptidoglycan-Induced Uveitis in Mice Free
PDF
Holly L. Rosenzweig; Kellen Galster; Emily E. Vance; Joe Ensign-Lewis; Gabriel Nunez; Michael P. Davey; James T. Rosenbaum
Tags: disease susceptibility, mice, peptidoglycan, uveitis
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4106-4112. doi:10.1167/iovs.10-6263
TAM Receptor Knockout Mice Are Susceptible to Retinal Autoimmune Induction Free
PDF
Fei Ye; Qiutang Li; Yan Ke; Qingjun Lu; Lixia Han; Henry J. Kaplan; Hui Shao; Qingxian Lu
Tags: autoimmune diseases, immunization, mice, mice, knockout, t-lymphocyte
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4239-4246. doi:10.1167/iovs.10-6700
Characterization of Langerin-Expressing Dendritic Cell Subsets in the Normal Cornea Free
PDF
Takaaki Hattori; Sunil K. Chauhan; Hyunsoo Lee; Hiroki Ueno; Reza Dana; Daniel H. Kaplan; Daniel R. Saban
Tags: cornea, corneal epithelium, dendritic cells, mice, skin
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4598-4604. doi:10.1167/iovs.10-6741
Sequence Variation in the Herpes Simplex Virus US1 Ocular Virulence Determinant Free
PDF
Aaron W. Kolb; Timothy R. Schmidt; David W. Dyer; Curtis R. Brandt
Tags: genes, human herpesvirus 1, proteins, simplexvirus, virulence
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4630-4638. doi:10.1167/iovs.10-7032
sPLA2-IIa Amplifies Ocular Surface Inflammation in the Experimental Dry Eye (DE) BALB/c Mouse Model Free
PDF
Yi Wei; Seth P. Epstein; Shima Fukuoka; Neil P. Birmingham; Xiu-Min Li; Penny A. Asbell
Tags: dry eye syndromes, inflammation, mice, mice, inbred balb c, secretory phospholipase a2
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4780-4788. doi:10.1167/iovs.10-6350
Differential Cell Proliferation, Apoptosis, and Immune Response in Healthy and Evaporative-Type Dry Eye Conjunctival Epithelia Free
PDF
Roberto Reinoso; Margarita Calonge; Evangelina Castellanos; Mario Martino; Itziar Fernández; Michael E. Stern; Alfredo Corell
Tags: apoptosis, conjunctiva, dry eye syndromes, immune response, signs and symptoms
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4819-4828. doi:10.1167/iovs.10-6073
Ocular Fibroblast Diversity: Implications for Inflammation and Ocular Wound Healing Free
PDF
Xia Xi; David H. McMillan; Geniece M. Lehmann; Patricia J. Sime; Richard T. Libby; Krystel R. Huxlin; Steven E. Feldon; Richard P. Phipps
Tags: fibroblasts, inflammation, cyclooxygenase-2, wound healing
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4859-4865. doi:10.1167/iovs.10-7066
The Effect of Nondialyzable Material (NDM) Cranberry Extract on Formation of Contact Lens Biofilm by Staphylococcus epidermidis Free
PDF
Rotem Leshem; Idit Maharshak; Eshel Ben Jacob; Itzhak Ofek; Israel Kremer
Tags: biofilms, contact lenses, staphylococcus epidermidis, bacteria
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4929-4934. doi:10.1167/iovs.10-5335
Calpain Inhibition Attenuates Apoptosis of Retinal Ganglion Cells in Acute Optic Neuritis Free
PDF
Amena W. Smith; Arabinda Das; M. Kelly Guyton; Swapan K. Ray; Baerbel Rohrer; Naren L. Banik
Tags: calpain, optic neuritis, retina, retinal ganglion cells, apoptosis
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4935-4941. doi:10.1167/iovs.10-7027
Tear Analytical Model Based on Raman Microspectroscopy for Investigation of Infectious Diseases of the Ocular Surface Free
PDF
Ming-Tse Kuo; Chi-Chang Lin; Hsin-Yu Liu; Hsien-Chang Chang
Tags: communicable diseases, corneal ulcer, infection
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4942-4950. doi:10.1167/iovs.10-7062

Lens

Proteomic Analysis of Human Age-related Nuclear Cataracts and Normal Lens Nuclei Free
PDF
Sheng Su; Ping Liu; Hong Zhang; Zhijian Li; Zhen Song; Lu Zhang; Shuo Chen
Tags: cataract, nuclear, cell nucleus, crystallins, lens (device), lens, crystalline
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4182-4191. doi:10.1167/iovs.10-7094
Resveratrol Prevention of Oxidative Stress Damage to Lens Epithelial Cell Cultures Is Mediated by Forkhead Box O Activity Free
PDF
Guorong Li; Coralia Luna; Iris D. Navarro; David L. Epstein; Wei Huang; Pedro Gonzalez; Pratap Challa
Tags: lens epithelial cell, oxidative stress, resveratrol, prevention
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4395-4401. doi:10.1167/iovs.10-6652
The Role of the Iris in Chick Accommodation Free
PDF
Lisa Anne Ostrin; Yue Liu; Vivian Choh; Christine F. Wildsoet
Tags: eye, immune reconstitution inflammatory syndrome, iris, nicotine, visual accommodation
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4710-4716. doi:10.1167/iovs.10-6819

Low Vision

Fixation Control before and after Treatment for Neovascular Age-Related Macular Degeneration Free
PDF
Esther G. González; Luminita Tarita-Nistor; Efrem D. Mandelcorn; Mark Mandelcorn; Martin J. Steinbach
Tags: aftercare, exudative age-related macular degeneration, eye, did not receive therapy or drug, visual acuity
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4208-4213. doi:10.1167/iovs.10-7026

Multidisciplinary Ophthalmic Imaging

Spatial Localization of A2E in the Retinal Pigment Epithelium Free
PDF
Angus C. Grey; Rosalie K. Crouch; Yiannis Koutalos; Kevin L. Schey; Zsolt Ablonczy
Tags: body tissue, diagnostic imaging, fluorescence, lipofuscin, mice
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 3926-3933. doi:10.1167/iovs.10-7020
Combined Nonlinear and Femtosecond Confocal Laser-Scanning Microscopy of Rabbit Corneas after Photochemical Cross-Linking Free
PDF
Alexander Krüger; Marine Hovakimyan; Diego F. Ramírez Ojeda; Oliver Stachs; Andreas Wree; Rudolf F. Guthoff; Alexander Heisterkamp
Tags: cornea, cross-linking, keratocytes, lasers, oryctolagus cuniculus
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4247-4255. doi:10.1167/iovs.10-7112
Light Scattering and Wavefront Aberrations in In Vivo Imaging of the Rat Eye: A Comparison Study Free
PDF
Christian van Oterendorp; Luis Diaz-Santana; Natalie Bull; Julia Biermann; Jens F. Jordan; Wolf A. Lagrèze; Keith R. Martin
Tags: diagnostic imaging, eye, comparative study research, cornea, optics
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4551-4559. doi:10.1167/iovs.10-6882
Quantification of Parapapillary Atrophy and Optic Disc Free
PDF
Cheng-Kai Lu; Tong Boon Tang; Augustinus Laude; Ian J. Deary; Baljean Dhillon; Alan F. Murray
Tags: atrophy, optic disk, color, eye
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4671-4677. doi:10.1167/iovs.10-6572
In Vivo Confocal Microscopy of Conjunctival Roundish Bright Objects: Young, Older, and Sjögren Subjects Free
PDF
Edoardo Villani; Silvia Beretta; Daniela Galimberti; Francesco Viola; Roberto Ratiglia
Tags: conjunctiva, microscopy, confocal, sjogren's syndrome, inflammatory cell, goblet cells
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4829-4832. doi:10.1167/iovs.10-6215

Nantotechnology and Regenerative Medicine

A Lipid Nanoparticle System Improves siRNA Efficacy in RPE Cells and a Laser-Induced Murine CNV Model Free
PDF
Hong-an Liu; Yu-ling Liu; Zhi-zhong Ma; Jian-cheng Wang; Qiang Zhang
Tags: choroidal neovascularization, lasers, lipids, retina, rna, small interfering
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4789-4794. doi:10.1167/iovs.10-5891

Physiology and Pharmacology

Functional Role of α1-Adrenoceptor Subtypes in Murine Ophthalmic Arteries Free
PDF
Adrian Gericke; Marcin L. Kordasz; Andreas Steege; Atsushi Sanbe; Evgeny Goloborodko; Jan M. Vetter; Andreas Patzak; Norbert Pfeiffer
Tags: adrenergic receptor, ophthalmic artery, mice, rna, messenger
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4795-4799. doi:10.1167/iovs.11-7516

Retina

Nutritional Manipulation of Primate Retinas, V: Effects of Lutein, Zeaxanthin, and n–3 Fatty Acids on Retinal Sensitivity to Blue-Light–Induced Damage Free
PDF
Felix M. Barker, II; D. Max Snodderly; Elizabeth J. Johnson; Wolfgang Schalch; Wolfgang Koepcke; Joachim Gerss; Martha Neuringer
Tags: blue light, lutein, omega-3 fatty acids, retina, primates
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 3934-3942. doi:10.1167/iovs.10-5898
Human Chorioretinal Layer Thicknesses Measured in Macula-wide, High-Resolution Histologic Sections Free
PDF
Christine A. Curcio; Jeffrey D. Messinger; Kenneth R. Sloan; Arnab Mitra; Gerald McGwin; Richard F. Spaide
Tags: body tissue, eye, macula densa, macula lutea, volume
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 3943-3954. doi:10.1167/iovs.10-6377
The Pathogenesis of Retinal Damage in Blunt Eye Trauma: Finite Element Modeling Free
PDF
Tommaso Rossi; Barbara Boccassini; Luca Esposito; Mario Iossa; Andrew Ruggiero; Ciro Tamburrelli; Nicola Bonora
Tags: eye, macula densa, macula lutea, ocular trauma, pathogenesis
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 3994-4002. doi:10.1167/iovs.10-6477
Variants in the APOE Gene Are Associated with Improved Outcome after Anti-VEGF Treatment for Neovascular AMD Free
PDF
Sanjeewa S. Wickremasinghe; Jing Xie; Jonathan Lim; Devinder S. Chauhan; Luba Robman; Andrea J. Richardson; Gregory Hageman; Paul N. Baird; Robyn Guymer
Tags: anti-vascular endothelial growth factor therapy, apolipoprotein e, exudative age-related macular degeneration, genes, treatment outcome
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4072-4079. doi:10.1167/iovs.10-6550
Experimental Model to Evaluate Mechanical Closure Resistance of Sutureless Vitrectomy Sclerotomies Using Pig Eyes Free
PDF
Lorenzo Lopez-Guajardo; Javier Benitez-Herreros; Agustin Silva-Mato
Tags: eye, sclerotomy, vitrectomy, intraocular pressure
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4080-4084. doi:10.1167/iovs.10-6812
Noninvasive Measurements and Analysis of Blood Velocity Profiles in Human Retinal Vessels Free
PDF
Zhangyi Zhong; Hongxin Song; Toco Yuen Ping Chui; Benno L. Petrig; Stephen A. Burns
Tags: velocity, retinal vessels
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4151-4157. doi:10.1167/iovs.10-6940
Mechanisms Underlying Benzyl Alcohol Cytotoxicity (Triamcinolone Acetonide Preservative) in Human Retinal Pigment Epithelial Cells Free
PDF
Yi-Sheng Chang; Chiou-Feng Lin; Chao-Liang Wu; Pao-Ying Kuo; Fong-Sen Wu; Chi-Chang Shieh; Po-Wu Gean; Shur-Tzu Chen; Muh-Shy Chen; Wen-Chuan Wu; Ming-Hong Tai; Sung-Huei Tseng
Tags: apoptosis, benzyl alcohol, caspases, culture media, cytotoxicity
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4214-4222. doi:10.1167/iovs.10-6058
Effects of Subretinal Electrical Stimulation in Mer-KO Mice Free
PDF
Julie A. Mocko; Moon Kim; Amanda E. Faulkner; Yang Cao; Vincent T. Ciavatta; Machelle T. Pardue
Tags: electric stimulation, mice, rats, electroretinography, tissue degeneration
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4223-4230. doi:10.1167/iovs.10-6750
Soluble Apoptotic Factors and Adhesion Molecules in Rhegmatogenous Retinal Detachment Free
PDF
Lukas J. A. G. Ricker; Raffaele Altara; Fleur Goezinne; Fred Hendrikse; Aize Kijlstra; Ellen C. La Heij
Tags: cell adhesion molecules, radiation recall dermatitis, retinal detachment, rhegmatogenous retinal detachment, surgical procedures, operative
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4256-4262. doi:10.1167/iovs.10-6892
Serum Carotenoids and Risk of Age-Related Macular Degeneration in a Chinese Population Sample Free
PDF
Haiying Zhou; Xianfeng Zhao; Elizabeth J. Johnson; Apiradee Lim; Erdan Sun; Jie Yu; Yinbo Zhang; Xipu Liu; Torkel Snellingen; Fu Shang; Ningpu Liu
Tags: age-related macular degeneration, carotenoids, chinese (other dialects), chinese people, lutein
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4338-4344. doi:10.1167/iovs.10-6519
Quantification of Contrast Recognizability during Brilliant Blue G– and Indocyanine Green–Assisted Chromovitrectomy Free
PDF
Paul B. Henrich; Siegfried G. Priglinger; Christos Haritoglou; Tatjana Josifova; Paulo R. Ferreira; Rupert W. Strauss; Josef Flammer; Philippe C. Cattin
Tags: brilliant blue g, dyes, indocyanine green, eye
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4345-4349. doi:10.1167/iovs.10-6972
microRNAs in Early Diabetic Retinopathy in Streptozotocin-Induced Diabetic Rats Free
PDF
Beatrix Kovacs; Stephen Lumayag; Colleen Cowan; Shunbin Xu
Tags: diabetes mellitus, micrornas, rats, streptozocin, retina
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4402-4409. doi:10.1167/iovs.10-6879
The α7-nicotinic Acetylcholine Receptor and MMP-2/-9 Pathway Mediate the Proangiogenic Effect of Nicotine in Human Retinal Endothelial Cells Free
PDF
Aaron M. Dom; Adam W. Buckley; Kathleen C. Brown; Richard D. Egleton; Aileen J. Marcelo; Nancy A. Proper; Donald E. Weller; Yashoni H. Shah; Jamie K. Lau; Piyali Dasgupta
Tags: angiogenesis, gelatinase a, nicotine, endothelial cells
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4428-4438. doi:10.1167/iovs.10-5461
The Dynamic Healing Process of Idiopathic Macular Holes after Surgical Repair: A Spectral-Domain Optical Coherence Tomography Study Free
PDF
Ferdinando Bottoni; Stefano De Angelis; Saverio Luccarelli; Mario Cigada; Giovanni Staurenghi
Tags: cyst, embryonic lethal mutation, follow-up, healing process, macular holes
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4439-4446. doi:10.1167/iovs.10-6732
Pax6 Regulates Proliferation and Apoptosis of Human Retinoblastoma Cells Free
PDF
Shu-wei Bai; Bin Li; Hao Zhang; Jost B. Jonas; Bo-wen Zhao; Ling Shen; Yi-chen Wang
Tags: apoptosis, retinoblastoma, rna, small interfering, gene silencing
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4560-4570. doi:10.1167/iovs.10-5487
Performance of Automated Drusen Detection by Polarization-Sensitive Optical Coherence Tomography Free
PDF
Ferdinand G. Schlanitz; Bernhard Baumann; Tobias Spalek; Christopher Schütze; Christian Ahlers; Michael Pircher; Erich Götzinger; Christoph K. Hitzenberger; Ursula Schmidt-Erfurth
Tags: drusen, optical coherence tomography
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4571-4579. doi:10.1167/iovs.10-6846
Pharmacokinetics of a Sustained-Release Dexamethasone Intravitreal Implant in Vitrectomized and Nonvitrectomized Eyes Free
PDF
Joan-En Chang-Lin; James A. Burke; Qing Peng; Ton Lin; Werhner C. Orilla; Corine R. Ghosn; Kai-Ming Zhang; Baruch D. Kuppermann; Michael R. Robinson; Scott M. Whitcup; Devin F. Welty
Tags: dexamethasone, eye, implants, intravitreal implants, pharmacokinetics
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4605-4609. doi:10.1167/iovs.10-6387
Identification of Urinary Biomarkers for Age-Related Macular Degeneration Free
PDF
Robyn H. Guymer; Lingwei W. Tao; Jonathan K. Goh; Danny Liew; Olga Ischenko; Liubov D. Robman; KhinZaw Aung; Tania Cipriani; Melinda Cain; Andrea J. Richardson; Paul N. Baird; Robyn Langham
Tags: age-related macular degeneration, biological markers, cytokine, urinary tract, monocyte chemoattractant protein-1
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4639-4644. doi:10.1167/iovs.10-7120
The Spectrum of Subclinical Best Vitelliform Macular Dystrophy in Subjects with Mutations in BEST1 Gene Free
PDF
Giuseppe Querques; Jennyfer Zerbib; Rossana Santacroce; Maurizio Margaglione; Nathalie Delphin; Lea Querques; Jean-Michel Rozet; Josseline Kaplan; Eric H. Souied
Tags: electrooculography, genes, mutation, vitelliform dystrophy, eye
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4678-4684. doi:10.1167/iovs.10-6500
Comparability of Digital Photography with the ETDRS Film Protocol for Evaluation of Diabetic Retinopathy Severity Free
PDF
Helen K. Li; Ronald P. Danis; Larry D. Hubbard; Jose F. Florez-Arango; Adol Esquivel; Elizabeth A. Krupinski
Tags: diabetic retinopathy, eye, mosaicism, photography, color
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4717-4725. doi:10.1167/iovs.10-6303
Pharmacokinetics of Pars Plana Intravitreal Injections versus Microcannula Suprachoroidal Injections of Bevacizumab in a Porcine Model Free
PDF
Timothy W. Olsen; Xiao Feng; Kathy Wabner; Karl Csaky; Stefan Pambuccian; J. Douglas Cameron
Tags: bevacizumab, body tissue, injection of therapeutic agent, intravitreal injections, pharmacokinetics
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4749-4756. doi:10.1167/iovs.10-6291
Integrity of the Cone Photoreceptor Mosaic in Oligocone Trichromacy Free
PDF
Michel Michaelides; Jungtae Rha; Elise W. Dees; Rigmor C. Baraas; Melissa L. Wagner-Schuman; John D. Mollon; Adam M. Dubis; Mette K. G. Andersen; Thomas Rosenberg; Michael Larsen; Anthony T. Moore; Joseph Carroll
Tags: mosaicism, retinal cone, personal integrity
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4757-4764. doi:10.1167/iovs.10-6659
Evaluation of a Computer-Aided Diagnosis System for Diabetic Retinopathy Screening on Public Data Free
PDF
Clara I. Sánchez; Meindert Niemeijer; Alina V. Dumitrescu; Maria S. A. Suttorp-Schulten; Michael D. Abràmoff; Bram van Ginneken
Tags: computer assisted diagnosis, diabetic retinopathy, screening, retinal diseases
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4866-4871. doi:10.1167/iovs.10-6633
Endovascular Coiling of the Ophthalmic Artery in Pigs to Induce Retinal Ischemia Free
PDF
Håkan Morén; Bodil Gesslein; Per Undrén; Sten Andreasson; Malin Malmsjö
Tags: endovascular embolization, ophthalmic artery, retinal ischemia, suidae, retina
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4880-4885. doi:10.1167/iovs.11-7628

Retinal Cell Biology

Effect of VEGF Trap on Normal Retinal Vascular Development and Oxygen-Induced Retinopathy in the Dog Free
PDF
Gerard A. Lutty; D. Scott McLeod; Imran Bhutto; Stanley J. Wiegand
Tags: dog, domestic, oxygen, thyroid hormone associated protein complex, vascular endothelial growth factor a, retinal diseases
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4039-4047. doi:10.1167/iovs.10-6798
Curcumin Attenuates Staurosporine-Mediated Death of Retinal Ganglion Cells Free
PDF
Balabharathi Burugula; Bhagyalaxmi S. Ganesh; Shravan K. Chintala
Tags: curcumin, retina, retinal ganglion cells
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4263-4273. doi:10.1167/iovs.10-7103
Microvascular Retinal Endothelial and Pericyte Cell Apoptosis In Vitro: Role of Hedgehog and Notch Signaling Free
PDF
Tony E. Walshe; Paul Connell; Lorna Cryan; Gail Ferguson; Tom Gardiner; David Morrow; Eileen M. Redmond; Colm O'Brien; Paul A. Cahill
Tags: apoptosis, endothelium, pericytes, pulsatile flow, signal transduction
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4472-4483. doi:10.1167/iovs.10-7061
Morphology and Immunoreactivity of Retrogradely Double-Labeled Ganglion Cells in the Mouse Retina Free
PDF
Ji-Jie Pang; Samuel M. Wu
Tags: glasgow coma scale, language morphology, mice, morphology, retina
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4886-4896. doi:10.1167/iovs.10-5921
Microarray Characterization of Human Embryonic Stem Cell–Derived Retinal Cultures Free
PDF
Deepak A. Lamba; Thomas A. Reh
Tags: embryonic stem cells, fetus, genes, retina, heat (physical force)
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4897-4906. doi:10.1167/iovs.10-6504
Relationship of Stokes Radius to the Rate of Diffusion across Bruch's Membrane Free
PDF
Astrid Zayas-Santiago; Alan D. Marmorstein; Lihua Y. Marmorstein
Tags: body tissue, bruch's basal membrane, diffusion, gel
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4907-4913. doi:10.1167/iovs.10-6595

Visual Neuroscience

Dopamine Modulates the Voltage Response of Human Rod Photoreceptors by Inhibiting the h Current Free
PDF
Fusao Kawai; Masayuki Horiguchi; Ei-ichi Miyachi
Tags: dopamine, rod photoreceptors, voltage
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4113-4117. doi:10.1167/iovs.10-6983
Intrinsically Photosensitive (Melanopsin) Retinal Ganglion Cell Function in Glaucoma Free
PDF
Beatrix Feigl; Dietmar Mattes; Ravi Thomas; Andrew J. Zele
Tags: glaucoma, melanopsin, retinal ganglion cells
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4362-4367. doi:10.1167/iovs.10-7069

Visual Psychophysics and Physiological Optics

Effects of Aging on Visual Contour Integration and Segmentation Free
PDF
Clara Casco; Valentina Robol; Michele Barollo; Selene Cansino
Tags: aging, contrast sensitivity, noise
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 3955-3961. doi:10.1167/iovs.10-5439
Adult Discrimination Performance for Pediatric Acuity Test Optotypes Free
PDF
T. Rowan Candy; Sylvia R. Mishoulam; Robert M. Nosofsky; Velma Dobson
Tags: adult, pediatrics, child
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4307-4313. doi:10.1167/iovs.10-6391
Statistical Eye Model for Normal Eyes Free
PDF
Jos J. Rozema; David A. Atchison; Marie-José Tassignon
Tags: eye, lens, crystalline, refraction, biometry
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4525-4533. doi:10.1167/iovs.10-6705

Clinical Trials

Randomized Clinical Trial Evaluating mETDRS versus Normal or High-Density Micropulse Photocoagulation for Diabetic Macular Edema Free
PDF
Daniel Lavinsky; Jose A. Cardillo; Luiz A. S. Melo, Jr; Alessandro Dare; Michel E. Farah; Rubens Belfort, Jr
Tags: clinical trials, lasers, light coagulation, macular edema, diabetic, visual acuity
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4314-4323. doi:10.1167/iovs.10-6828
Effect of Latanoprost on Choroidal Blood Flow Regulation in Healthy Subjects Free
PDF
Agnes Boltz; Doreen Schmidl; Günther Weigert; Michael Lasta; Berthold Pemp; Hemma Resch; Gerhard Garhöfer; Gabriele Fuchsjäger-Mayrl; Leopold Schmetterer
Tags: intraocular pressure, latanoprost, placebos, regulation, vascular flow
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4410-4415. doi:10.1167/iovs.11-7263
Transcorneal Electrical Stimulation for Patients with Retinitis Pigmentosa: A Prospective, Randomized, Sham-Controlled Exploratory Study Free
PDF
Andreas Schatz; Tobias Röck; Lubka Naycheva; Gabriel Willmann; Barbara Wilhelm; Tobias Peters; Karl Ulrich Bartz-Schmidt; Eberhart Zrenner; André Messias; Florian Gekeler
Tags: electric stimulation, electroretinography, retinitis pigmentosa, accommodation phosphene, visual fields
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4485-4496. doi:10.1167/iovs.10-6932
Morphometric Analysis of Optic Nerves and Retina from an End-Stage Retinitis Pigmentosa Patient with an Implanted Active Epiretinal Array Free
PDF
Jeffrey G. Eng; Rajat N. Agrawal; Kevin R. Tozer; Fred N. Ross-Cisneros; Gislin Dagnelie; Robert J. Greenberg; Gerald J. Chader; James D. Weiland; Narsing A. Rao; Alfredo A. Sadun; Mark S. Humayun
Tags: eye, optic nerve, retina, retinitis pigmentosa, implantation procedure
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4610-4616. doi:10.1167/iovs.09-4936
Testing of Semichronically Implanted Retinal Prosthesis by Suprachoroidal-Transretinal Stimulation in Patients with Retinitis Pigmentosa Free
PDF
Takashi Fujikado; Motohiro Kamei; Hirokazu Sakaguchi; Hiroyuki Kanda; Takeshi Morimoto; Yasushi Ikuno; Kentaro Nishida; Haruhiko Kishima; Tomoyuki Maruo; Kunihiko Konoma; Motoki Ozawa; Kohji Nishida
Tags: accommodation phosphene, retinitis pigmentosa, surgical procedures, operative, visual prosthesis, perception
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4726-4733. doi:10.1167/iovs.10-6836
A Method to Measure and Predict Rates of Regional Visual Field Decay in Glaucoma Free
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Joseph Caprioli; Dennis Mock; Elena Bitrian; Abdelmonem A. Afifi; Fei Yu; Kouros Nouri-Mahdavi; Anne L. Coleman
Tags: glaucoma, visual fields, eye, cataract, follow-up
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4765-4773. doi:10.1167/iovs.10-6414
A Method to Measure and Predict Rates of Regional Visual Field Decay in Glaucoma Free
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Joseph Caprioli; Dennis Mock; Elena Bitrian; Abdelmonem A. Afifi; Fei Yu; Kouros Nouri-Mahdavi; Anne L. Coleman
Tags: glaucoma, visual fields, eye, cataract, follow-up
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4765-4773. doi:10.1167/iovs.10-6414

Perspective

Can the Hair Follicle Become a Model for Studying Selected Aspects of Human Ocular Immune Privilege? Free
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Michael Kinori; Jennifer E. Kloepper; Ralf Paus
Tags: heart failure, eye, hair follicle, palmar-plantar erythrodysesthesia syndrome
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4447-4458. doi:10.1167/iovs.10-7154

Lecture

Introducing Richard H. Masland, the 2010 Recipient of the Proctor Medal Free
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Heinz Wässle
Tags: acetylcholine, mice, retina, retinal diseases
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4580. doi:10.1167/iovs.10-7104
Cell Populations of the Retina: The Proctor Lecture Free
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Richard H. Masland
Tags: retina, amacrine cells, retinal bipolar cells
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4581-4591. doi:10.1167/iovs.10-7083

Letters to the Editor

Innate Resistance of Corneas to Pathogen Infections Free
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Yiqiang Wang
Tags: cornea, infection, pathogenic organism
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4192. doi:10.1167/iovs.11-7594
Incorrect Citation Free
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David O. Bates
Tags: bevacizumab, choroidal neovascularization, endothelial cells, eye melanomas, mice
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4368. doi:10.1167/iovs.11-7310
Author Response: Incorrect Citation Free
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Hua Yang; Hans E. Grossniklaus
Tags: angiogenesis inhibitors, bevacizumab, choroidal neovascularization, corneal neovascularization, eye
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4368. doi:10.1167/iovs.11-7341
Blink Efficiency: A Neglected Area Of Ocular Surface Disease Management? Free
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Charles W. McMonnies
Tags: disease management
Investigative Ophthalmology & Visual Science June 2011, Vol.52, 4484. doi:10.1167/iovs.11-7751
Copyright © 2015 Association for Research in Vision and Ophthalmology.
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