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Clinical and Epidemiologic Research January 2024

Smoking, Corneal Biomechanics, and Glaucoma: Results From Two Large Population-Based Cohorts

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Kelsey V. Stuart; Kian M. Madjedi; Robert N. Luben; Mahantesh I. Biradar; Siegfried K. Wagner; Alasdair N. Warwick; Zihan Sun; Pirro G. Hysi; Mark J. Simcoe; Paul J. Foster; Anthony P. Khawaja; on behalf of the Modifiable Risk Factors for Glaucoma Collaboration and the UK Biobank Eye and Vision Consortium
TAGS: biomechanics, cohort studies, cornea, glaucoma, smoking, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):11. https://doi.org/10.1167/iovs.65.1.11

Includes: Supplemental Content

Clinical and Epidemiologic Research August 2023

Metabolite and Lipid Biomarkers Associated With Intraocular Pressure and Inner Retinal Morphology: 1 H NMR Spectroscopy Results From the UK Biobank

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Louis R. Pasquale; Anthony P. Khawaja; Janey L. Wiggs; Jihye Kim; Pirro Hysi; Tobias Elze; Jessica Lasky-Su; Jae H. Kang; Oana Zeleznik; for the UK Biobank Eye and Vision Consortium
TAGS: biobanks, biological markers, intraocular pressure, metabolites, lipids, spectrum analysis
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):11. https://doi.org/10.1167/iovs.64.11.11

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Associations of Retinal Vascular Morphology and Inflammatory Bowel Disease: A cross-sectional analysis.

Laxmi Raja; Timing Liu; Yukun Zhou; Robbert Struyven; Dominic Williamson; Mario Cortina Borja; David Romero-Bascones; Anthony P Khawaja; Praveen J Patel; Daniel Alexander; Konstantinos Balaskas; Jugnoo Rahi; Alastair K Denniston; Axel Petzold; Siegfried Wagner; Pearse Keane

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3734.

ARVO Annual Meeting Abstract June 2023

Periodontal disease and outer retinal morphology: A cross-sectional analysis of the UK Biobank cohort

Josef Christian Huemer; Siegfried Wagner; Praveen J Patel; Mario Cortina Borja; Robbert Struyven; David Romero-Bascones; Dominic Williamson; Anthony P Khawaja; Axel Petzold; Konstantinos Balaskas; Iain Chapple; Thomas Dietrich; Jugnoo Rahi; Alastair K Denniston; Pearse Keane

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):237.

ARVO Annual Meeting Abstract June 2023

The association of physical activity with glaucoma and related traits in the UK Biobank

Kian Madjedi; Kelsey Vernon Stuart; Sharon Chua; Pradeep Y Ramulu; Alasdair Warwick; Robert Luben; Zihan Sun; Mark Chia; Hughes Aschard; Janey L Wiggs; Jae H Kang; Louis R Pasquale; Paul Foster; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2904.

ARVO Annual Meeting Abstract June 2023

Retinal biomarkers for systemic diseases: an oculome-wide association study in 164,784 individuals

Timing Liu; Siegfried Wagner; Robbert Struyven; Yukun Zhou; Dominic Williamson; David Romero-Bascones; Mateo Gende Lozano; NIKOLAS PONTIKOS; Praveen J Patel; Mario Cortina Borja; Jugnoo Rahi; Axel Petzold; Anthony P Khawaja; Alastair K Denniston; Konstantinos Balaskas; Pearse Keane

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):459.

ARVO Annual Meeting Abstract June 2023

Age Prediction from Retinal Fundus Images and Segmented Vessel Images using Deep Learning

Yushan Wang; Timing Liu; Dominic Williamson; Robbert Struyven; Yukun Zhou; David Romero-Bascones; Mateo Gende Lozano; Konstantinos Balaskas; Mario Cortina Borja; Jugnoo Rahi; Axel Petzold; Anthony P Khawaja; Alastair K Denniston; Siegfried Wagner; Pearse Keane

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1105.

Retina February 2023

Associations Between HbA1c Across the Normal Range, Diagnosed, and Undiagnosed Diabetes and Retinal Layer Thickness in UK Biobank Cohort

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Sharon Y.L. Chua; Paul Welsh; Zihan Sun; Konstantinos Balaskas; Alasdair Warwick; David Steel; Sobha Sivaprasad; Roomasa Channa; Tony Ko; Naveed Sattar; Anthony P. Khawaja; Paul J. Foster; Praveen J. Patel; on behalf of The UK Biobank Eye and Vision Consortium
TAGS: biobanks, cohort studies, diabetes mellitus, diabetes mellitus, type 2, hemoglobin a, glycosylated, undiagnosed
Trans. Vis. Sci. Tech.. 2023; 12(2):25. https://doi.org/10.1167/tvst.12.2.25

Includes: Supplemental Content

Glaucoma February 2023

Genetic Associations Between Smoking- and Glaucoma-Related Traits

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Jessica H. Tran; Kelsey V. Stuart; Victor de Vries; Joëlle E. Vergroesen; Clara C. Cousins; Pirro G. Hysi; Ron Do; Ghislain Rocheleau; Jae H. Kang; Janey L. Wiggs; Stuart MacGregor; Anthony P. Khawaja; David A. Mackey; Caroline C. W. Klaver; Wishal D. Ramdas; Louis R. Pasquale; for the UK Biobank Eye and Vision Consortium, and for the International Glaucoma Genetics Consortium
TAGS: genetics, glaucoma, smoking
Trans. Vis. Sci. Tech.. 2023; 12(2):20. https://doi.org/10.1167/tvst.12.2.20

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2022

Potential for Collider Bias in Studies Examining the Association of Central Corneal Thickness With Glaucoma

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Anthony P. Khawaja; Nomdo M. Jansonius
TAGS: cornea, glaucoma, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2022; 63(12):3. https://doi.org/10.1167/iovs.63.12.3

Glaucoma June 2022

High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study

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Denis Plotnikov; Yu Huang; Anthony P. Khawaja; Paul J. Foster; Zhuoting Zhu; Jeremy A. Guggenheim; Mingguang He
TAGS: blood pressure, glaucoma, hypertension, intraocular pressure, mendelian randomization analysis, open-angle glaucoma
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):29. https://doi.org/10.1167/iovs.63.6.29

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Association of lipid-lowering drugs, anti-diabetic drugs, non-steroidal anti-inflammatory drugs, and levodopa with age-related macular degeneration in Europeans: A meta-analysis of the European Eye Epidemiology (E3) – consortium

Matthias Marten Marten Mauschitz; Alexander Karl-Georg Schuster; Anthony P Khawaja; Mukharram Bikbov; Ruth E. Hogg; Franziska G Rauscher; Maja Gran Erke; Fotis Topouzis; Caroline Brandl; Catherine Creuzot-Garcher; Cecile Delcourt; Hans-Werner Hense; Rufino Silva; Stefano Piermarocchi; Karen Ritchie; Robert P Finger

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):378 – F0209.

ARVO Annual Meeting Abstract June 2022

Genetic correlations between smoking- and glaucoma-related traits

Jessica H. Tran; Kelsey V. Stuart; Clara Cousins; Pirro G Hysi; Anthony P Khawaja; Ron Do; Shantanu Bafna; Jae Kang; Jiali Wang; Stuart MacGregor; Janey L Wiggs; Louis R Pasquale

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1133.

ARVO Annual Meeting Abstract June 2022

Association of commonly used systemic medications with glaucoma prevalence and intraocular pressure across Europe: the E3 Consortium

Alexander Karl-Georg Schuster; Joëlle Vergroesen; Kelsey Vernon Stuart; Geir Bertelsen; Fotis Topouzis; Mukharram Bikbov; Catherine Creuzot-Garcher; Cecile Delcourt; Rufino Silva; Nomdo M Jansonius; Franziska G Rauscher; Caroline C W Klaver; Norbert Pfeiffer; Wishal D Ramdas; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2267.

Clinical and Epidemiologic Research May 2022

Statin Use in Relation to Intraocular Pressure, Glaucoma, and Ocular Coherence Tomography Parameters in the UK Biobank

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Jihye Kim; Marianne T. Kennedy Neary; Hugues Aschard; Mathew M. Palakkamanil; Ron Do; Janey L. Wiggs; Anthony P. Khawaja; Louis R. Pasquale; Jae H. Kang; for the International Glaucoma Genetics Consortium (IGGC), UK Biobank Eye and Vision Consortium, and Modifiable Risk Factors for Glaucoma Collaboration
TAGS: biobanks, glaucoma, intraocular pressure, statins
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):31. https://doi.org/10.1167/iovs.63.5.31

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2021

The Association of Ambient Air Pollution With Cataract Surgery in UK Biobank Participants: Prospective Cohort Study

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Sharon Y. L. Chua; Anthony P. Khawaja; Parul Desai; Jugnoo S. Rahi; Alex C. Day; Christopher J. Hammond; Peng T. Khaw; Paul J. Foster
TAGS: air pollution, biobanks, cataract surgery, prospective studies, cataract
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):7. https://doi.org/10.1167/iovs.62.15.7

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Combining glaucoma and correlated risk factors dramatically expands gene discovery for glaucoma

Stuart MacGregor; Xikun Han; Puya Gharahkhani; Maciej Trzaskowski; Jamie E Craig; Alex W Hewitt; David A Mackey; Janey L Wiggs; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1512.

Clinical and Epidemiologic Research February 2021

Association Between Medication-Taking and Refractive Error in a Large General Population-Based Cohort

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Karina Patasova; Anthony P. Khawaja; Bani Tamraz; Katie M. Williams; Omar A. Mahroo; Maxim Freidin; Ameenat L. Solebo; Jelle Vehof; Mario Falchi; Jugnoo S. Rahi; Chris J. Hammond; Pirro G. Hysi
TAGS: cohort studies, pharmaceutical preparations, refraction, refractive errors, drug usage, protein electrophoresis, serum
Invest. Ophthalmol. Vis. Sci.. 2021; 62(2):15. https://doi.org/10.1167/iovs.62.2.15

Includes: Supplemental Content

Genetics September 2020

The Role of Chromosome X in Intraocular Pressure Variation and Sex-Specific Effects

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Mark J. Simcoe; Anthony P. Khawaja; Omar A. Mahroo; Christopher J. Hammond; Pirro G. Hysi; for the UK Biobank Eye and Vision Consortium
TAGS: intraocular pressure, open-angle glaucoma, x chromosomes, single nucleotide polymorphism, biobanks, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):20. https://doi.org/10.1167/iovs.61.11.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Long-term experience of XEN® trans-scleral gelatin stent insertion in a large specialist glaucoma center

Yusrah Shweikh; Georgios Vakros; Alexander Baneke; Sam Cooke; Anthimos Vlavianos; Anthony P Khawaja; Keith Barton; Hari Jayaram

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):941.

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Smoking, Corneal Biomechanics, and Glaucoma: Results From Two Large Population-Based Cohorts

Metabolite and Lipid Biomarkers Associated With Intraocular Pressure and Inner Retinal Morphology: 1 H NMR Spectroscopy Results From the UK Biobank

Associations of Retinal Vascular Morphology and Inflammatory Bowel Disease: A cross-sectional analysis.

Periodontal disease and outer retinal morphology: A cross-sectional analysis of the UK Biobank cohort

The association of physical activity with glaucoma and related traits in the UK Biobank

Retinal biomarkers for systemic diseases: an oculome-wide association study in 164,784 individuals

Age Prediction from Retinal Fundus Images and Segmented Vessel Images using Deep Learning

Associations Between HbA1c Across the Normal Range, Diagnosed, and Undiagnosed Diabetes and Retinal Layer Thickness in UK Biobank Cohort

Genetic Associations Between Smoking- and Glaucoma-Related Traits

Potential for Collider Bias in Studies Examining the Association of Central Corneal Thickness With Glaucoma

High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study

Association of lipid-lowering drugs, anti-diabetic drugs, non-steroidal anti-inflammatory drugs, and levodopa with age-related macular degeneration in Europeans: A meta-analysis of the European Eye Epidemiology (E3) – consortium

Genetic correlations between smoking- and glaucoma-related traits

Association of commonly used systemic medications with glaucoma prevalence and intraocular pressure across Europe: the E3 Consortium

Statin Use in Relation to Intraocular Pressure, Glaucoma, and Ocular Coherence Tomography Parameters in the UK Biobank

The Association of Ambient Air Pollution With Cataract Surgery in UK Biobank Participants: Prospective Cohort Study

Combining glaucoma and correlated risk factors dramatically expands gene discovery for glaucoma

Association Between Medication-Taking and Refractive Error in a Large General Population-Based Cohort

The Role of Chromosome X in Intraocular Pressure Variation and Sex-Specific Effects

Long-term experience of XEN® trans-scleral gelatin stent insertion in a large specialist glaucoma center

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