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ARVO Annual Meeting Abstract June 2023

Tear protein biomarkers for pain after refractive surgery: candidate discovery

BROOKE HARKNESS; Deborah Hegarty; Larry L David; Siting Chen; Jodi Lapidus; Julie Saugstad; Hannah Behrens; Winston Chamberlain; Richard Stutzman; Maricarmen Perez-Blanco; Jason Betz; Anat Galor; Sue Aicher

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):197.

ARVO Annual Meeting Abstract June 2023

Playing “redox hot potato”: disulfide transfer between γ-crystallins in the aging, pre-cataractous lens

David Thorn; Eugene Serebryany; Larry L David; Kirsten J Lampi; Eugene Shakhnovich

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1230.

Genetics August 2022

Consequences of a Rare Complement Factor H Variant for Age-Related Macular Degeneration in the Amish

PDF

Andrea R. Waksmunski; Kristy Miskimen; Yeunjoo E. Song; Michelle Grunin; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Larry D. Adams; Laura Caywood; Michael Prough; Dwight Stambolian; William K. Scott; Margaret A. Pericak-Vance; Jonathan L. Haines
TAGS: age-related macular degeneration, alleles, complement factor h, proteins, c-reactive protein, rna
Invest. Ophthalmol. Vis. Sci.. 2022; 63(9):8. https://doi.org/10.1167/iovs.63.9.8

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Detection of tear protein biomarkers associated with contact lens use

BROOKE M HARKNESS; Deborah Hegarty; Hannah Behrens; Larry David; Keith Zientek; Julie Saugstad; Jodi Lapidus; Winston Chamberlain; Richard Stutzman; Maricarmen Perez-Blanco; Jason Betz; Anat Galor; Sue Aicher

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3948 – A0228.

ARVO Annual Meeting Abstract June 2022

Deamidation in human gammaS-crystallin increases susceptibility to glutathione induced oxidation and aggregation

Kirsten J Lampi; Keith Zientek; Samuel G Wheeler; David Anderson; Ujwal P Shinde; Larry L David

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2304.

ARVO Annual Meeting Abstract June 2022

Creation of a semi-synthetic γS-crystallin to support studies of age-related modifications in cataract

Larry L David; Victoria S Halls; Keith Zientek; Francis I Valiyaveetil; Ravikumar Reddi; Kate A Haverson; Ujwal P Shinde; Kirsten J Lampi

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2301.

Glaucoma December 2021

Compositional Analysis of Extracellular Aggregates in the Eyes of Patients With Exfoliation Syndrome and Exfoliation Glaucoma

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Alicia De Maria; Keith D. Zientek; Larry L. David; Phillip A. Wilmarth; Anjali M. Bhorade; George J. Harocopos; Andrew J.W. Huang; Augustine R. Hong; Carla J. Siegfried; Linda M. Tsai; Arsham Sheybani; Steven Bassnett
TAGS: exfoliation syndrome, eye, hypertension, lens capsule, crystalline, peeling of skin, proteins, fibrillin-1, proteome, mass spectrometry
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):27. https://doi.org/10.1167/iovs.62.15.27

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Upon oxidation, deamidated gammaS-crystallin has increased aggregation compared to wild type gammaS-crystallin

Kirsten J Lampi; Samuel Wheeler; Keith Zientek; Larry L David

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2093.

ARVO Annual Meeting Abstract June 2021

Lens crystallin destabilization by ascorbylation: Mapping of glycation sites associated with protein insolubilization

Vincent M Monnier; Keith Zientek; Grant Hom; Shiyuan Dong; Larry L David; David R Sell

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2091.

ARVO Annual Meeting Abstract June 2020

Genetic prescreening of candidates for laser refractive surgery identifies at risk patients for inadequate tissue response where current technologies lead to diagnostic uncertainty

Andrea Cusumano; Hila Roshanravan; Connie Chao-Shern; Tara Moore; Jacopo Sebastiani; Jung Hee Levialdi Ghiron; Larry DeDionisio

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2432.

ARVO Annual Meeting Abstract June 2020

Celf1 regulates the small heat shock protein Hspb8 in lens development

Francisco Hernandez; Sabrina Luther; Sandeep Aryal; Bailey A.T. Weatherbee; Archana Devi Siddam; Ashok P. Reddy; Philip Wilmarth; Larry David; Carole Gautier-Courteille; Luc Paillard; Salil A. Lachke

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2870.

ARVO Annual Meeting Abstract June 2020

Surface deamidations increase susceptibility to aggregation and oxidation-induced aggregation of gammaS-crystallin without protein unfolding

Kirsten J Lampi; Larry David; Calvin Vetter; Samuel Wheeler

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3479.

ARVO Annual Meeting Abstract July 2019

Three loci associated with risk of advanced age-related macular degeneration (AMD) also influence anti-VEGF treatment response

William K Scott; Omar García Rodríguez; Patrice Whitehead-Gay; Larry D. Adams; Jacob K. Welch; Renee Laux; Milam A Brantley; Jaclyn L. Kovach; Stephen G Schwartz; Anita Agarwal; Jonathan L Haines; Margaret A Pericak-Vance

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2968.

ARVO Annual Meeting Abstract July 2019

Identification of PKCα-dependent phosphoproteins in mouse retina

Catherine W Morgans; Colin M Wakeham; Philip A Wilmarth; Gaoying Ren; john E Klimek; Jennifer M Cunliffe; Larry L David

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):578.

ARVO Annual Meeting Abstract July 2019

Developmental expression of zebrafish αBa- and αBb-crystallin and the effect of their loss by CRISPR gene editing

Mason Posner; Brandon Andrew; Kelly Lynn Murray; Emmaline Kepp; Dylan Farnsworth; Adam Miller; Larry L David

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4289.

ARVO Annual Meeting Abstract July 2019

Lens β-crystallins preferentially form hetero-oligomers

Kirsten J Lampi; Micah Donor; Takumi Takata; Calvin Vetter; Larry L David; James Prell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4797.

ARVO Annual Meeting Abstract July 2019

Effect of surface deamidations on structure and stability of γS crystallins

Calvin Vetter; Kate Halverson; Ido Almog; Larry L David; Kirsten J Lampi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5689.

Biochemistry and Molecular Biology October 2018

Lacrimal Gland Denervation Alters Tear Protein Composition and Impairs Ipsilateral Eye Closures and Corneal Nociception

PDF

Deborah M. Hegarty; Larry L. David; Sue A. Aicher
TAGS: cornea, denervation, eye, lacrimal gland, proteins, sensory perception, rats, pain perception, lacrimal nerve
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5217-5224. https://doi.org/10.1167/iovs.18-25267

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Investigation of a rare risk variant in complement factor H for age-related macular degeneration in the Amish

Andrea R. Waksmunski; Kristy Miskimen; Yeunjoo E. Song; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Larry D. Adams; Laura Caywood; Michael Prough; William K Scott; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1420.

ARVO Annual Meeting Abstract July 2018

Common Variants in KLHL2 and C4orf50 Are Associated with Poorer Anti-VEGF Treatment Response in Age-Related Macular Degeneration

Omar García Rodríguez; Samuel Shuoyuan Pan; Patrice Patrice; Larry D. Adams; Jacob Welch; Renee Laux; Jorge Fortun; Milam A Brantley; Jaclyn Kovach,; Stephen G Schwartz; Anita Agarwal; Jonathan Haines; Margaret A Pericak-Vance; William Scott

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1425.

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Tear protein biomarkers for pain after refractive surgery: candidate discovery

Playing “redox hot potato”: disulfide transfer between γ-crystallins in the aging, pre-cataractous lens

Consequences of a Rare Complement Factor H Variant for Age-Related Macular Degeneration in the Amish

Detection of tear protein biomarkers associated with contact lens use

Deamidation in human gammaS-crystallin increases susceptibility to glutathione induced oxidation and aggregation

Creation of a semi-synthetic γS-crystallin to support studies of age-related modifications in cataract

Compositional Analysis of Extracellular Aggregates in the Eyes of Patients With Exfoliation Syndrome and Exfoliation Glaucoma

Upon oxidation, deamidated gammaS-crystallin has increased aggregation compared to wild type gammaS-crystallin

Lens crystallin destabilization by ascorbylation: Mapping of glycation sites associated with protein insolubilization

Genetic prescreening of candidates for laser refractive surgery identifies at risk patients for inadequate tissue response where current technologies lead to diagnostic uncertainty

Celf1 regulates the small heat shock protein Hspb8 in lens development

Surface deamidations increase susceptibility to aggregation and oxidation-induced aggregation of gammaS-crystallin without protein unfolding

Three loci associated with risk of advanced age-related macular degeneration (AMD) also influence anti-VEGF treatment response

Identification of PKCα-dependent phosphoproteins in mouse retina

Developmental expression of zebrafish αBa- and αBb-crystallin and the effect of their loss by CRISPR gene editing

Lens β-crystallins preferentially form hetero-oligomers

Effect of surface deamidations on structure and stability of γS crystallins

Lacrimal Gland Denervation Alters Tear Protein Composition and Impairs Ipsilateral Eye Closures and Corneal Nociception

Investigation of a rare risk variant in complement factor H for age-related macular degeneration in the Amish

Common Variants in KLHL2 and C4orf50 Are Associated with Poorer Anti-VEGF Treatment Response in Age-Related Macular Degeneration

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