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ARVO Annual Meeting Abstract June 2023

New trans -modifier genes in the most common monogenic eye disorder, ABCA4/Stargardt disease.

Jana Zernant; Winston Lee; Takayuki Nagasaki; PEI-YIN SU; Stephen H. Tsang; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2798.

ARVO Annual Meeting Abstract June 2023

The Glycine Cleavage System in Retinal Metabolism and Disease

Caleb Bates; Esther Lim; Regis Fallon; Takayuki Nagasaki; Rando Allikmets; Martina Wallace; Christian M Metallo; Martin Friedlander; Marin Gantner

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3510.

ARVO Annual Meeting Abstract June 2022

A common haplotype in the PRPH2 gene modifies Stargardt/ABCA4 disease.

Jana Zernant; Winston Lee; Jun Wang; KERRY GOETZ; Ehsan Ullah; Takayuki Nagasaki; PEI-YIN SU; Gerald A Fishman; Stephen H Tsang; Santa J Tumminia; Brian Brooks; Robert B Hufnagel; Rui Chen; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1596 – A0385.

ARVO Annual Meeting Abstract June 2022

Vitelliform foveomacular lesions in ABCA4 disease: A phenotypic expansion and longitudinal study

PEI-YIN SU; Winston Lee; Jana Zernant; Takayuki Nagasaki; Stephen H Tsang; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3752 – F0173.

ARVO Annual Meeting Abstract June 2022

Identifying critical diagnostic features that distinguish ABCA4 disease from its Mendelian phenocopies

Winston Lee; Jana Zernant; Takayuki Nagasaki; Stephen H Tsang; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3745 – F0166.

ARVO Annual Meeting Abstract June 2021

Clinical and Genetics Characterization of Hypomorphic Variants in Stargardt disease

Winston Lee; Jana Zernant; Takayuki Nagasaki; Gerald A Fishman; Stephen H Tsang; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2171.

ARVO Annual Meeting Abstract June 2021

Characterization of Stargardt disease patient-derived human retinal organoids harboring the p.Gly1961Glu mutation in the ABCA4 gene

PEI-YIN SU; Jen-Zen Chuang; Winston Lee; Jana Zernant; Stephen H Tsang; Takayuki Nagasaki; Ching-Hwa Sung; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2595.

Articles August 2020

Topical Corneal Cross-Linking Solution Delivered Via Corneal Reservoir in Dutch-Belted Rabbits

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Mariya Zyablitskaya; Charles Jayyosi; Anna Takaoka; Kristin M. Myers; Leejee H. Suh; Takayuki Nagasaki; Stephen L. Trokel; David C. Paik
TAGS: cornea, corneal collagen cross-linking, cross-linking, oryctolagus cuniculus, dutch, optical pachymetry, epithelium, intraocular pressure
Trans. Vis. Sci. Tech.. 2020; 9(9):20. https://doi.org/10.1167/tvst.9.9.20

ARVO Annual Meeting Abstract July 2019

Multilamellar bodies: Clues to their role in aging retinal epithelium

Peter Gouras; Kristy R Brown; Julie A Mattison; Martha Neuringer; Takayuki Nagasaki; Lena Ivert

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1240.

ARVO Annual Meeting Abstract July 2019

Case-control collapsing analysis identifies genes mimicking Stargardt/ABCA4 disease

Chu Jian Ma; Charles Wolock; Nicholas Stong; Takayuki Nagasaki; Winston Lee; David Goldstein; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2935.

ARVO Annual Meeting Abstract July 2019

Characteristic ocular features in cases of autosomal recessive PROM1 cone-rod dystrophy

Frederick T Collison; Gerald A. Fishman; Takayuki Nagasaki; J Jason McAnany; Jason C Park; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4512.

ARVO Annual Meeting Abstract July 2019

MacTel patients carry rare phosphoglycerate dehydrogenase (PHGDH) variants with reduced enzymatic activity

Regis Fallon; Rebecca Berlow; Jana Zernant; Takayuki Nagasaki; Marin Gantner; Sarah Harkins-Perry; Kevin Eade; Rando Allikmets; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5994.

ARVO Annual Meeting Abstract July 2019

Comparative Evaluation of Typical and Atypical Pterygia Using Stem Cell and Germ Cell Markers

Rebecca Weiss; Maria Abadi; Alexandra Herzlich; Takayuki Nagasaki; JOYCE MBEKEANI

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6254.

ARVO Annual Meeting Abstract July 2019

Evaluation of a topical corneal cross-linking solution using sodium hydroxymethylglycinate by intravital confocal microscopy in the Dutch-belted rabbit: a follow up report on keratocyte morphologic changes.

David C Paik; Mariya Zyablitskaya; Anna Takaoka; Jaya R. Mehta; Estee Hong; Sara Fallahi; Leejee Suh; Takayuki Nagasaki; Stephen L. Trokel

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):354.

Genetics May 2019

Characteristic Ocular Features in Cases of Autosomal Recessive PROM1 Cone-Rod Dystrophy

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Frederick T. Collison; Gerald A. Fishman; Takayuki Nagasaki; Jana Zernant; J. Jason McAnany; Jason C. Park; Rando Allikmets
TAGS: autosomal recessive inheritance, diagnostic imaging, electroretinography, progressive cone-rod dystrophy, retinitis pigmentosa, family, spectral domain-optical coherence tomography, autofluorescence, color, genetic analysis
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2347-2356. https://doi.org/10.1167/iovs.19-26993

ARVO Annual Meeting Abstract July 2018

Rare variants in the phosphoglycerate dehydrogenase (PHGDH) gene in MacTel patients lead to decreased enzymatic activity

Regis Fallon; Jana Zernant; Takayuki Nagasaki; Marin Gantner; sarah harkins-perry; Kevin Eade; Rando Allikmets; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5409.

ARVO Annual Meeting Abstract July 2018

Lipidosis in aging monkey retinal epithelium

Peter Gouras; Takayuki Nagasaki; Martha Neuringer; Lena Ivert

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6061.

ARVO Annual Meeting Abstract July 2018

Sodium hydroxymethylglycinate via eyedrop for corneal cross-linking in Dutch-belted rabbits: a comparison of 40mM (0.5%) vs 80mM (1%) concentrations

Mariya Zyablitskaya; Daeryl Amponin; Anna Takaoka; Charles Jayyosi; Kristin Myers; Connie Chen; Leejee Suh; Takayuki Nagasaki; Stephen Trokel; David C Paik

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):748.

Cornea January 2018

Antimicrobial Studies Using the Therapeutic Tissue Cross-Linking Agent, Sodium Hydroxymethylglycinate: Implication for Treating Infectious Keratitis

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Patrick B. Rapuano; Alexandra H. Scanameo; Daeryl E. Amponin; Sefy A. Paulose; Mariya Zyablitskaya; Anna Takaoka; Leejee H. Suh; Takayuki Nagasaki; Stephen L. Trokel; David C. Paik
TAGS: antimicrobials, body tissue, cross-linking, keratitis, sodium, methicillin-resistant staphylococcus aureus
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):332-337. https://doi.org/10.1167/iovs.17-23111

Multidisciplinary Ophthalmic Imaging August 2017

Evaluation of Therapeutic Tissue Crosslinking (TXL) for Myopia Using Second Harmonic Generation Signal Microscopy in Rabbit Sclera

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Mariya Zyablitskaya; Anna Takaoka; Emilia L. Munteanu; Takayuki Nagasaki; Stephen L. Trokel; David C. Paik
TAGS: body tissue, harmonics, myopia, oryctolagus cuniculus, sclera, eye, riboflavin, injections, corneal collagen cross-linking
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):21-29. https://doi.org/10.1167/iovs.16-20241

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New trans -modifier genes in the most common monogenic eye disorder, ABCA4/Stargardt disease.

The Glycine Cleavage System in Retinal Metabolism and Disease

A common haplotype in the PRPH2 gene modifies Stargardt/ABCA4 disease.

Vitelliform foveomacular lesions in ABCA4 disease: A phenotypic expansion and longitudinal study

Identifying critical diagnostic features that distinguish ABCA4 disease from its Mendelian phenocopies

Clinical and Genetics Characterization of Hypomorphic Variants in Stargardt disease

Characterization of Stargardt disease patient-derived human retinal organoids harboring the p.Gly1961Glu mutation in the ABCA4 gene

Topical Corneal Cross-Linking Solution Delivered Via Corneal Reservoir in Dutch-Belted Rabbits

Multilamellar bodies: Clues to their role in aging retinal epithelium

Case-control collapsing analysis identifies genes mimicking Stargardt/ABCA4 disease

Characteristic ocular features in cases of autosomal recessive PROM1 cone-rod dystrophy

MacTel patients carry rare phosphoglycerate dehydrogenase (PHGDH) variants with reduced enzymatic activity

Comparative Evaluation of Typical and Atypical Pterygia Using Stem Cell and Germ Cell Markers

Evaluation of a topical corneal cross-linking solution using sodium hydroxymethylglycinate by intravital confocal microscopy in the Dutch-belted rabbit: a follow up report on keratocyte morphologic changes.

Characteristic Ocular Features in Cases of Autosomal Recessive PROM1 Cone-Rod Dystrophy

Rare variants in the phosphoglycerate dehydrogenase (PHGDH) gene in MacTel patients lead to decreased enzymatic activity

Lipidosis in aging monkey retinal epithelium

Sodium hydroxymethylglycinate via eyedrop for corneal cross-linking in Dutch-belted rabbits: a comparison of 40mM (0.5%) vs 80mM (1%) concentrations

Antimicrobial Studies Using the Therapeutic Tissue Cross-Linking Agent, Sodium Hydroxymethylglycinate: Implication for Treating Infectious Keratitis

Evaluation of Therapeutic Tissue Crosslinking (TXL) for Myopia Using Second Harmonic Generation Signal Microscopy in Rabbit Sclera

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