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ARVO Annual Meeting Abstract June 2020

Tivanisiran as a new treatment for Dry Eye in patients with Sjögren Syndrome

Victoria Gonzalez; Veronica Ruz; Anne Marie Bleau; Beatriz Vargas; Ana Isabel Jimenez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):102.

ARVO Annual Meeting Abstract July 2019

SYL1801: Preclinical Efficacy and Safety of a siRNA-based eye drops treatment for Age Related Macular Degeneration

Ana Isabel Jimenez; Veronica Ruz; Laura Rico; Tamara Martinez; Susana Monteiro; Ascension Cuesta; Amor Guerra; Alba Cuenca; Victoria Gonzalez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5389.

ARVO Annual Meeting Abstract July 2019

Clinical Results of tivanisiran, a siRNA for the treatment of dry eye disease

Veronica Ruz; Victoria Gonzalez; Anne-Marie Bleau; Beatriz Vargas; Ana Isabel Jimenez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6738.

ARVO Annual Meeting Abstract July 2019

Safety & effect of tivanisiran eye drops on ocular surface: corneal sensitivity, mucin production and proinflammatory mediator’s expression

Victoria Gonzalez; Beatriz Vargas; Tamara Martinez; Amor Guerra; Veronica Ruz; Ana Isabel Jimenez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6746.

ARVO Annual Meeting Abstract July 2018

Topical administration of siRNA targeting NRARP as a new treatment for choroidal neovascularization

Veronica Ruz; Covadonga Paneda; Tamara Martinez; Susana Monteiro; Amor Guerra; Victoria Gonzalez; Ana Isabel Jimenez

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2634.

ARVO Annual Meeting Abstract July 2018

Development of a RNAi therapeutic for the treatment of allergic conjunctivitis

Victoria Gonzalez; Covadonga Paneda; Tamara Martinez; Amor Guerra; Susana Monteiro; Beatriz Vargas; Anne Marie Bleau; Veronica Ruz; Ana Isabel Jimenez

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5567.

ARVO Annual Meeting Abstract July 2018

Tivanisiran, a new treatment for Dry Eye Disease, that improved signs and symptoms in clinical trials

Ana Isabel Jimenez; Veronica Ruz; Victoria Gonzalez; Covadonga Paneda; Tamara Martinez; Beatriz Vargas; Anne Marie Bleau

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):925.

ARVO Annual Meeting Abstract July 2018

Structural and funcional findings measured with macular OCT and microperimetry in presymptomatic patients with myotonic dystrophy type 1

Nayelli Rodríguez; Adriana Solis; DALILA RODRIGUEZ; Victoria del Carmen Gonzalez

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1537.

ARVO Annual Meeting Abstract July 2018

Optical Coherence Tomography Angiography in Patients with Diabetic Macular Edema treated with anti-VEGF intravitreal injections in Mexican Population

Alejandro Olguin; Adriana Solis; Victoria del Carmen Gonzalez; DALILA RODRIGUEZ

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3605.

ARVO Annual Meeting Abstract June 2017

Efficacy of SYL1001 in different animal models of Dry Eye Disease

Ana Isabel Jimenez; Covadonga Pañeda; Tamara Martinez; Amor Guerra; Nuno Fonseca; Susana Monteiro; Cristian Salvador; Jesus Merayo-Lloves; Ignacio Alcalde; Veronica Ruz; Victoria Gonzalez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):458.

ARVO Annual Meeting Abstract June 2017

Stability study of SYL1001 eye drops (a siRNA compound) for Dry Eye Disease in different containers

Veronica Ruz; Yolanda Ruiz; Carlos Astrain; Carlos Segura; Noelia Miguel; Carlos millan; Victoria Gonzalez; Maria D Company

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):476.

ARVO Annual Meeting Abstract June 2017

Clinical and preclinical study correlation for SYL1001, a new treatment for dry eye disease

Victoria Gonzalez; Veronica Ruz; Covadonga Pañeda; Anne-Marie Bleau; Beatriz Vargas; Ana Isabel Jimenez

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2670.

Cornea November 2016

Safety and Efficacy Clinical Trials for SYL1001, a Novel Short Interfering RNA for the Treatment of Dry Eye Disease

PDF

José Manuel Benitez-Del-Castillo; Javier Moreno-Montañés; Ignacio Jiménez-Alfaro; Francisco José Muñoz-Negrete; Krista Turman; Kadi Palumaa; Belén Sádaba; María Victoria González; Verónica Ruz; Beatriz Vargas; Covadonga Pañeda; Tamara Martínez; Anne-Marie Bleau; Ana Isabel Jimenez
TAGS: dry eye syndromes, placebos, rna, rna, small interfering, safety, phase 2 clinical trials, eye
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6447-6454. https://doi.org/10.1167/iovs.16-20303

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Results of clinical trials with a novel RNA-based therapy (SYL1001) to treat patients with ocular pain associated to dry eye disease

Ana Isabel Jimenez; Jose M Benitez Del Castillo; Javier Moreno-Montanes; Ignacio Jimenez-Alfaro; Francisco Muñoz-Negrete; Kadi Palumaa; Krista Turman; Covadonga Paneda; Tamara Martinez; Veronica Ruz; Victoria Gonzalez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2878.

ARVO Annual Meeting Abstract September 2016

Results of Phase IIB SYLTAG clinical trial with bamosiran in patients with glaucoma

Victoria Gonzalez; Javier Moreno-Montanes; Maris Oll; Kenneth N Sall; Kadi Palumaa; Harvey Dubiner; Krista Turman; Francisco Muñoz-Negrete; Veronica Ruz; Ana Isabel Jimenez

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3023.

ARVO Annual Meeting Abstract September 2016

Stability study of Bamosiran (a siRNA compound) in ophthalmic solution in different containers

Veronica Ruz; Victoria Gonzalez; Ana Isabel Jimenez; Lola Company; Yolanda Ruiz; Carlos Astrain

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3040.

ARVO Annual Meeting Abstract June 2015

In search of association between the VEGF gene polymorphisms: rs3025035, rs3025021, rs2010963 and proliferative diabetic retinopathy in Mexican population.

Roberto Gonzalez-Salinas; Juan Carlos Solis-Sainz; Maria Carlota Garcia-Gutierrez; Gerardo Garcia-Aguirre; Vidal Soberon; Victoria Gonzalez; Rodrigo Lechuga; Vinicio Garcia-Solis; Virgilio Morales

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1463.

ARVO Annual Meeting Abstract June 2015

Pharmacokinetic and Biosdistribution of Bamosiran in Human and Animal model, a Novel Treatment for Glaucoma

Victoria Gonzalez; Belen Sadaba; Javier Moreno-Montanes; Veronica Ruz; Covadonga Paneda; Ana Isabel Jimenez

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5748.

ARVO Annual Meeting Abstract June 2015

Development of a RNAi therapeutic for the treatment of allergic conjunctivitis

Ana Isabel Jimenez; Tamara Martinez; Victoria Gonzalez; Carmen Martinez-Garcia; Covadonga Paneda

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4883.

ARVO Annual Meeting Abstract June 2015

Prevalence of epiretinal membrane (ERM) in rhegmatogenous retinal detachment (RRD) after pars plana vitrectomy by means of spectral domain optical coherence tomography (SD-OCT).

Luis Arroyo; Victoria Gonzalez; Valentina Franco-Cardenas; Raul Velez-Montoya; Jans Fromow; Virgilio Morales

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5098.

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Tivanisiran as a new treatment for Dry Eye in patients with Sjögren Syndrome

SYL1801: Preclinical Efficacy and Safety of a siRNA-based eye drops treatment for Age Related Macular Degeneration

Clinical Results of tivanisiran, a siRNA for the treatment of dry eye disease

Safety & effect of tivanisiran eye drops on ocular surface: corneal sensitivity, mucin production and proinflammatory mediator’s expression

Topical administration of siRNA targeting NRARP as a new treatment for choroidal neovascularization

Development of a RNAi therapeutic for the treatment of allergic conjunctivitis

Tivanisiran, a new treatment for Dry Eye Disease, that improved signs and symptoms in clinical trials

Structural and funcional findings measured with macular OCT and microperimetry in presymptomatic patients with myotonic dystrophy type 1

Optical Coherence Tomography Angiography in Patients with Diabetic Macular Edema treated with anti-VEGF intravitreal injections in Mexican Population

Efficacy of SYL1001 in different animal models of Dry Eye Disease

Stability study of SYL1001 eye drops (a siRNA compound) for Dry Eye Disease in different containers

Clinical and preclinical study correlation for SYL1001, a new treatment for dry eye disease

Safety and Efficacy Clinical Trials for SYL1001, a Novel Short Interfering RNA for the Treatment of Dry Eye Disease

Results of clinical trials with a novel RNA-based therapy (SYL1001) to treat patients with ocular pain associated to dry eye disease

Results of Phase IIB SYLTAG clinical trial with bamosiran in patients with glaucoma

Stability study of Bamosiran (a siRNA compound) in ophthalmic solution in different containers

In search of association between the VEGF gene polymorphisms: rs3025035, rs3025021, rs2010963 and proliferative diabetic retinopathy in Mexican population.

Pharmacokinetic and Biosdistribution of Bamosiran in Human and Animal model, a Novel Treatment for Glaucoma

Development of a RNAi therapeutic for the treatment of allergic conjunctivitis

Prevalence of epiretinal membrane (ERM) in rhegmatogenous retinal detachment (RRD) after pars plana vitrectomy by means of spectral domain optical coherence tomography (SD-OCT).

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