RT Journal Article
A1 Joachim, Nichole
A1 Rochtchina, Elena
A1 Tan, Ava Grace
A1 Hong, Thomas
A1 Mitchell, Paul
A1 Wang, Jie Jin
T1 Right and Left Correlation of Retinal Vessel Caliber Measurements in Anisometropic Children: Effect of Refractive ErrorAnisometropia and Retinal Vessel Caliber
JF Investigative Ophthalmology & Visual Science
JO IOVS
YR 2012
DO 10.1167/iovs.12-9422
JF Investigative Ophthalmology & Visual Science
VO 53
IS 9
SP 5227
OP 5230
SN 1552-5783
AB Previous studies have reported high right–left eye correlation in retinal vessel caliber. We test the hypothesis that right–left correlation in retinal vessel caliber would be reduced in anisometropic compared with emmetropic children. Retinal arteriolar and venular calibers were measured in 12-year-old children. Three groups were selected: group 1, both eyes emmetropic (n = 214); group 2, right–left spherical equivalent refraction (SER) difference ≥1.00 but <2.00 diopter (D) (n = 35); and group 3, right–left SER difference ≥2.00 D (n = 32). Pearson's correlations between the two eyes were compared between group 1 and group 2 or 3. Associations between right–left difference in refractive error and right–left difference in caliber measurements were assessed using linear regression models. Right–left correlation in group 1 was 0.57 for central retinal arteriolar equivalent (CRAE) and 0.70 for central retinal venular equivalent (CRVE) compared with 0.60 and 0.82 for CRAE and CRVE, respectively, in group 2 (P = 0.42 and P = 0.08), and 0.36 and 0.52, respectively, in group 3 (P = 0.08 and P = 0.07, referenced to group 1). Each 1.00-D increase in right–left SER difference was associated with a 0.74-μm increase in mean CRAE difference (P = 0.02) and a 1.23-μm increase in mean CRVE difference between the two eyes (P = 0.002). Each 0.1-mm increase in right–left difference in axial length was associated with a 0.21-μm increase in the mean difference in CRAE (P = 0.01) and a 0.42-μm increase in the mean difference in CRVE (P < 0.0001) between the two eyes. Refractive error ≥2.00 D may contribute to variation in measurements of retinal vessel caliber.
RD 6/20/2019
UL https://doi.org/10.1167/iovs.12-9422