RT Journal Article
A1 Mulholland, Pádraig J.
A1 Redmond, Tony
A1 Garway-Heath, David F.
A1 Zlatkova, Margarita B.
A1 Anderson, Roger S.
T1 Estimating the Critical Duration for Temporal Summation of Standard Achromatic Perimetric Stimuli
JF Investigative Ophthalmology & Visual Science
JO IOVS
YR 2015
DO 10.1167/iovs.14-15304
JF Investigative Ophthalmology & Visual Science
VO 56
IS 1
SP 431
OP 437
SN 1552-5783
AB    To estimate the critical duration of temporal summation for achromatic Goldmann III stimuli under the conditions of standard automated perimetry (SAP) and quantify response variability for short-duration stimuli.    Contrast thresholds were gathered using the method of constant stimuli for seven circular (0.48° diameter) incremental stimuli of varying duration (sum-of-frames equivalent: 8.3–198.3 ms), at an eccentricity of 8.8° along the four principal meridians of the visual field in two healthy, psychophysically experienced observers. Stimuli were presented on a high-resolution cathode ray tube display with a background luminance of 10 cd/m2. Psychometric functions were fitted using a probit model and nonparametric local-linear analysis. The critical duration was estimated using iterative two-phase regression analysis, the results also being compared with values produced using previously published methods of analysis.    The median critical duration estimated using iterative two-phase regression analysis was 27.7 ms (IQR 22.5–29.8). A slight steepening of the psychometric function slope (lower variability) was observed for longer stimulus durations, using both probit and local-linear analysis techniques, but this was not statistically significant.    Critical duration estimates in this study are substantially shorter than those previously reported for a Goldmann III stimulus, under the conditions of SAP. Further work is required to firmly establish the relationship between measurement variability and the degree of local temporal and spatial summation.  
RD 12/16/2019
UL https://doi.org/10.1167/iovs.14-15304