RT Journal Article
A1 Liu, Hongting
A1 Li, Jing
A1 Agbedia, Owhofasa
A1 Wang, Jiangxia
A1 Li, Xinyu
A1 Wang, Hujie
A1 Liu, Lei
T1 Higher-order Aberrations after Posterior Chamber Phakic Intraocular lens Implantation 
JF Investigative Ophthalmology & Visual Science
JO Invest. Ophthalmol. Vis. Sci.
YR 2015
VO 56
IS 7 
SP 2971
OP 2971
SN 1552-5783
AB  PurposeTo evaluate the changes of higher-order aberrations (HOAs) after implantable collamer lenses implantations (Visian ICL; STAAR Surgical Co, Monrovia, California, USA). MethodsIn this prospective study, thirty-three eyes of 20 patients with myopia who had ICL implantation were enrolled. Before surgery and one month after surgery, the wavefront aberration data were obtained with the Hartmann-Shack wavefront sensor (KR-1W aberrometer, Topcon Corp, Tokyo, Japan). For patients with pupil size < 6 mm, the root mean square (RMS) of total ocular HOAs, RMS of third-order aberrations, RMS of fourth-order aberrations were measured and analyzed for 4 mm-pupil diameter. For patients with pupil size ≥ 6 mm, HOAs were calculated for 6 mm-pupil diameter. Visual acuity, refraction, pupil size and intra ocular pressures were also recorded. ResultsSignificant improvements in visual acuities were found postoperatively, with significant reduction in spherical equivalent (P < 0.001). All HOAs in the 6 mm-pupil group were significantly higher than that of the 4 mm-pupil group, this was observed prior to and after the procedure.<br /> <br /> After one month of the implantation of ICL, the induction of total ocular HOAs, third-order aberrations, and fourth-order aberrations in 4mm-pupil group were were 0.002 ± 0.061 μm, - 0.004 ± 0.045 μm, and 0.001 ± 0.039 μm, respectively. In the 6-mm pupil group, the induction of total HOAs, third-order aberrations, and fourth-order aberrations were 0.089 ± 0.144 μm, 0.042 ± 0.117 μm, and 0.034 ± 0.060 μm, respectively. The increase in total HOAs and third-order aberrations were not statistically significant after the procedure in both groups (all P > 0.05), however, the increase in fourth-order aberrations was statistically significant in the 6mm-pupil group. ConclusionsICL implantation results in an improvement in visual acuity with minor increase in HOAs among eyes with 4 mm and 6 mm-pupils. Larger longitudinal studies, with a greater number of subjects are indicated to confirm these findings.  Table 1 and Table 2    Figure 1   
RD 8/12/2020