RT Journal Article
A1 Horgan, N.
A1 Shields, C. L.
A1 Mashayekhi, A.
A1 Materin, M. A.
A1 Salazar, P. F.
A1 O'Regan, M.
A1 Shields, J. A.
T1  Macular Edema Following Plaque Radiotherapy of Uveal Melanoma: A Proposed OCT-Based Grading System
JF Investigative Ophthalmology & Visual Science
JO Invest. Ophthalmol. Vis. Sci.
YR 2008
VO 49
IS 13
SP 48
OP 48
SN 1552-5783
AB    To assess the relaibility and validity of an optical coherence tomography (OCT) based grading scale for macular edema following plaque radiotherapy of uveal melanoma.     An inter-rater reliability study of a proposed five point grading scale was conducted. Assessment of the correlation between the grading scale, foveal thickness and visual acuity measurements in 139 eligible patients with a diagnosis of radiation-induced macular oedema was then undertaken.     The grading scale was highly reliable (kappa=0.91, z = 32.96, p=0.000). The grading scale also correlated with foveal thickness (Spearman’s correlation coefficient [rho] =0.56, p<0.0001) and visual acuity (rho =0.39, p<0.0001).     This pilot study suggests that OCT-based methods are feasible in the grading of macular edema following plaque radiatiotherapy of uveal melanoma.   
RD 4/12/2021