RT Journal Article A1 Chacko, D. M. A1 Roth, E. D. T1 25-Gauge Vitrectomy and Membrane Peel in Management of Idiopathic Epiretinal Membranes JF Investigative Ophthalmology & Visual Science JO Invest. Ophthalmol. Vis. Sci. YR 2008 VO 49 IS 13 SP 4673 OP 4673 SN 1552-5783 AB To determine effectiveness of 25-gauge vitrectomy and membrane peel of idiopathic epiretinal membranes. Optical coherence tomography and visual acuity scores were evaluated in a retrospective look at 21 patients who underwent a membrane peel and 25-gauge vitrectomy for epiretinal membranes. The preoperative data was compared to the postoperative data with a mean of 3.5 months follow up. Surgery resulted in a decrease in macular thickness in all patients. The preoperative mean for all patients decreased from 429 ± 71 microms to 317 ± 48 microms after surgery. Visual acuity increased from a mean of 20/70+1 (range: 20/30 to 20/150) to a mean of 20/50+2 (range: 20/15 to 20/150) postoperatively. Of the 21 patients, 15 (71.4%) had an increase in their visual acuity (average gain: 13 letters), while 3 (14.3%) had a decrease in visual acuity (average loss: 11 letters). Three patients (14.3%) had no change in visual acuity. Fourteen patients (67%) had a postoperative VA of ≥20/50. 25-Gauge vitrectomy and membrane peel are effective in reducing macular edema and increasing visual acuity. Further study with longer follow-up and comparison needs to be done to determine if 25-gauge vitrectomy is more effective than standard 20-gauge vitrectomy. RD 3/3/2021