RT Journal Article
A1 REBOLLO RAMIREZ, MARIA FERNANDA
A1 Pedroza-Seres, Miguel
A1 Diarte, Deisy
T1 Neuroretinitis: Causes, clinical presentation and outcomes in an ophthalmology-specialized hospital in Mexico in 9 years
JF Investigative Ophthalmology & Visual Science
JO Invest. Ophthalmol. Vis. Sci.
YR 2017
VO 58
IS 8
SP 2179
OP 2179
SN 1552-5783
AB    Due to the small amount of investigations with the purpose of finding all the causes of neuroretinitis, the aim of this study is to look for all de causes of Neurorretinitis, the clinical manifestations and the outcomes in an ophthalmology-specialized hospital in Mexico from 2007 to 2016.    Descriptive, retrospective and longitudinal study. We included all the patients who attended to the Instituto de Oftalmología Fundación Conde de Valenciana from January 2007 to November 2016, whose diagnosis was Neuroretinitis.    There were 63 patients with the diagnosis of Neuroretinitis (1.07% of all de patients seen in the Uvea department in that period of time). We excluded 17 patients who only attended to one consultation. The age range of the 46 patients was 9-64 years (mean 34.04 years, median 29.5 years). The male:female ratio was 1:1. The cause of neuroretinitis was unknown in 20 patients (43.47%). 16 (34.78%) had a proven infectious cause: 6 patients had Toxoplasma gondii, 3 had syphilis, 2 had Borrelia burdorferi, 2 had Bartonella henselae, 1 had Brucella abortus, 1 had tuberculosis and 1 developed acute retinal necrosis by herpes simplex virus. In 6 patients (13.04%) the cause was autoimmune: Vogt-Konayagi-Harada syndrome (VKH) in 3 patients, systemic lupus erythematosus (SLE) in 1 patient, Eales disease in 1 patient, 1 patient had Takayasu arteritis. 3 patients had hypertensive retinopathy, and one had a neovascular membrane. Unilateral affection was present in 65.21% of the general group, 75% of infectious group, 33.33% of the autoimmune group and 75% of the group of unknown cause. Inflammatory cells in anterior chamber and vitreous, papillary hemorrhages, initial and final visual acuitiy were also studied and compared between the groups.    Cat scratch disease (CSD) is by far not the only cause of neuroretinitis. The most common infectious cause in our population is toxoplasmosis. VKH,Takayasu arteritis, LES and Eales disease can present initially with neuroretinitis. Affection of only one eye is the most common presentarion. When the cause is infectious it’s more probable the affection of only one eye, when the cause is autoimmune it’s more common that both eyes are involved. There are no sex or age predilection.  This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017. 
RD 4/21/2021