February 1971
Volume 10, Issue 2
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Articles  |   February 1971
Effect of Essential Fatty Acid Deficiency on the Fatty Acid Composition, Morphology, and Electroretinographic Response of the Retina
Author Affiliations
  • SIDNEY FUTTERMAN
    Department of Ophthalmology, University of Washington Medical School, Seattle, Wash.
  • JOHN L. DOWNER
    Department of Ophthalmology, University of Washington Medical School, Seattle, Wash.
  • ANITA HENDRICKSON
    Department of Ophthalmology, University of Washington Medical School, Seattle, Wash.
Investigative Ophthalmology & Visual Science February 1971, Vol.10, 151-156. doi:
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      SIDNEY FUTTERMAN, JOHN L. DOWNER, ANITA HENDRICKSON; Effect of Essential Fatty Acid Deficiency on the Fatty Acid Composition, Morphology, and Electroretinographic Response of the Retina. Invest. Ophthalmol. Vis. Sci. 1971;10(2):151-156.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Essential fatty acid deficiency has been produced in rats without superimposing a deficiency of vitamin A. The fatty acid composition of normal and deficient rat tissues was determined. Retina and brain were much less changed in composition by essential fatty acid deficiency than other tissues. The electroretinographic response was only slightly altered. A loss of mural cells from the retinal capillaries was the only morphologic change observed.

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