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JOEL SUGAR, RONALD M. BURDE, ALAN SUGAR, STEPHEN R. WALTMAN, K. J. KRIPALANI, IRVING WELIKY, BERNARD BECKER; Tetrahydrotriamcinolone and Triamcinolone I. Ocular Penetration. Invest. Ophthalmol. Vis. Sci. 1972;11(11):890-893.
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© ARVO (1962-2015); The Authors (2016-present)
Triamcinolone (TA) and tetrahydrotriamcinolone (THTA) are very similar in structure, but only one, TA, consistently raises intraocular pressure in susceptible individuals. It has been postulated that these differences are due to differing penetration qualities. In the present study, using anterior chamber paracentesis in human eyes, these drugs were very similar in ocular penetration.
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