Vitreous Structure III. Composition of Bovine Vitreous Collagen

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Abstract

Amino acid analyses have shown that the major component of the insoluble fibrous proteins in the bovine vitreous is a collagen similar to that found in cartilage. Heat denaturation (55° C. for 15 minutes) solubilized 0.3 per cent of the vitreous collagen which migrated as a single major component when examined by disc electrophoresis. The mobility of this band corresponded to a. chains from skin collagen. It is concluded that vitreous collagen is composed of α₁ type II polypeptide chains.