Original Articles: The filtration coefficient of the intraocular vasculature as measured by low-pressure perfusion in a primate eye

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Abstract

Anterior chamber perfusion of a series of rhesus monkey eyes was carried out at intraocular pressure levels above and below episcleral venous pressure. For intraocular pressures above venous pressure the slope of the flow-pressure curve was a measure of total facility of the eye. The average value for total facility ivas found to be 0.66 ± 0.11 µL min^-1 mm. Hg^-1 which is in good agreement with previously published data for the rhesus monkeys similarly anesthetized. The slope of the flow-pressure curve at intraocidar pressures below venous pressure was a measure of the filtration coefficient of the intraocular vascular tree. The filtration coefficient determined by this technique was found to be 0.30 ± 0.06 µL min^-1 mm. Hg^-1. These data are in good agreement with the value for the filtration coefficient determined previously using osmotic transient experiments in the same species