May 1973
Volume 12, Issue 5
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Articles  |   May 1973
Original Articles: The filtration coefficient of the intraocular vasculature as measured by low-pressure perfusion in a primate eye
Author Affiliations
  • RICHARD F. BRUBAKER
    Eye Physiology Laboratory, the Department of Ophthalmology, The Mayo Clinic Rochester, Minn. Veterans Administration Hospital, the Department of Ophthalmology, College of Medicine, University of Florida Gainesville, Fla.
  • DAVID M. WORTHEN
    Eye Physiology Laboratory, the Department of Ophthalmology, The Mayo Clinic Rochester, Minn. Veterans Administration Hospital, the Department of Ophthalmology, College of Medicine, University of Florida Gainesville, Fla.
Investigative Ophthalmology & Visual Science May 1973, Vol.12, 321-326. doi:https://doi.org/
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      RICHARD F. BRUBAKER, DAVID M. WORTHEN; Original Articles: The filtration coefficient of the intraocular vasculature as measured by low-pressure perfusion in a primate eye. Invest. Ophthalmol. Vis. Sci. 1973;12(5):321-326. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Anterior chamber perfusion of a series of rhesus monkey eyes was carried out at intraocular pressure levels above and below episcleral venous pressure. For intraocular pressures above venous pressure the slope of the flow-pressure curve was a measure of total facility of the eye. The average value for total facility ivas found to be 0.66 ± 0.11 µL min-1 mm. Hg-1 which is in good agreement with previously published data for the rhesus monkeys similarly anesthetized. The slope of the flow-pressure curve at intraocidar pressures below venous pressure was a measure of the filtration coefficient of the intraocular vascular tree. The filtration coefficient determined by this technique was found to be 0.30 ± 0.06 µL min-1 mm. Hg-1. These data are in good agreement with the value for the filtration coefficient determined previously using osmotic transient experiments in the same species

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