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Abstract
Argon laser burns of varying intensity (50 mW./0.2 sec/50 µ, 100 mW./0.1 sec/100 µ, 100 mW./0.2 sec/200 µ, and 100 mW./0.2 sec/400 µ) were made in the region of the maculopapillar bundle of four human eyes 24 hours prior to enucleation for malignant melanoma of the choroid. Light and electron microscopic observations revealed that it is possible to produce chorioretinal lesions between the disc and the macula without damaging the nerve fiber layer of the maculopapillar bundle. In order for this to be accomplished blood vessels should be avoided and the intensity of the argon laser should not exceed 50 mW./0.2 sec/50 µ. These small lesions may be of benefit in the treatment of conditions like central serous retinopathy, histoplasmosis, and senile macular degeneration and deserve further clinical investigation.