Fibrinolytic Activity of the Vitreous Body

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Abstract

The vitreous bodies of human, dog, and sheep eyes were examined for the presence of fibrinolytic activity by two different methods. In spite of previous conflicting evidence, the results suggest that there is little doubt as to the presence of plasminogen activator in small quantities within the vitreous. Moreover, its behavioral characteristics conform to those of tissue activator as opposed to plasma activator. Its origin within the vitreous and its relationship to intravitreal hemorrhage are discussed.