August 1974
Volume 13, Issue 8
Free
Articles  |   August 1974
Ocular Manifestations of Marek's Disease
THOMAS W. SMITH; DANIEL M. ALBERT; NANCY ROBINSON; BRUCE W. CALNEK; OTTO SCHWABE
Author Affiliations
  • THOMAS W. SMITH
    Department of Ophthalmology, Yale University School of Medicine, New Haven, Conn.
  • DANIEL M. ALBERT
    Department of Ophthalmology, Yale University School of Medicine, New Haven, Conn.
  • NANCY ROBINSON
    Department of Ophthalmology, Yale University School of Medicine, New Haven, Conn.
  • BRUCE W. CALNEK
    Department of Avian Diseases, New York State University College, Cornell University, Ithaca, N. Y.
  • OTTO SCHWABE
    N. Y. Rutgers Health Laboratory, Rutgers University, Vineland, N. J.
Investigative Ophthalmology & Visual Science August 1974, Vol.13, 586-592. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      User Alerts
      You are adding an alert for:
      Ocular Manifestations of Marek's Disease
      You will receive an email whenever this article is corrected, updated, or cited in the literature. You can manage this and all other alerts in My Account
      The alert will be sent to:
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation
      Citation

      THOMAS W. SMITH, DANIEL M. ALBERT, NANCY ROBINSON, BRUCE W. CALNEK, OTTO SCHWABE; Ocular Manifestations of Marek's Disease. Invest. Ophthalmol. Vis. Sci. 1974;13(8):586-592.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

      ×
    • Get Permissions
  • Supplements
This content is PDF only. Please click on the PDF icon to access.
Abstract

An experimental study of the ocular changes occurring in Marek's disease was carried out. Marek's disease which is induced by a DNA virus, is a disorder that occurs in chickens and related fowl. Ocular involvement is a feature of this disease. In this study the eye changes of Marek's disease were sequentially examined in specific, pathogen-free birds injected with clone purified Marek's disease virus. An infiltration of malignant-appearing lymphoreticular proliferative cells was seen initially in the optic nerves, ciliary nerves, and uvea in birds receiving the virus either intraocularly or systemically. Subsequent infiltration of similar cells occurred throughout the eye.

Copyright 1974 The Association for Research in Vision and Ophthalmology, Inc.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept