Localization of ³⁵Sulfated Macromolecules at the Site of Active Transport in the Ciliary Processes

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Abstract

Autoradiography shows that the unpigmented epithelium of the ciliary body incorporates ³⁵sulfate into macromolecules that move to the basal surface of the cell. The labeled macromolecules appear to be in the cell membrane and may be sxdfatides, glycolipids known to be associated with the Na⁺-K⁺-dependent ATPase responsible for active transport of sodium in other types of cells. In the ciliary processes, sulfatides would be involved in the secretion of aqueous humor. Lens epithelium appears to synthesize similar sulfated macromolecules that move to the apical (lens fiber) surface of the cell.