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STEPHEN E. BLOOMFIELD, STUART I. BROWN; Conjunctival Collagenase: Partial Purification. Invest. Ophthalmol. Vis. Sci. 1974;13(7):547-550.
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Collagenase is produced by both the normal and inflamed conjunctiva. The cell of origin is probably the epithelium. Inhibition could be carried out by the usual inhibitors. Partial purification of the enzyme from the inflamed tissue showed a discrete peak of activity at a molecular weight of 65,000. It is suggested that an abnormal production of collagenase by the conjunctiva may play a role in the formation of peripheral corneal ulcers and scleromalacia.
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